Results 121 to 130 of about 518 (150)
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Archaeosomes for Skin Injuries
2017This book presents new approaches for skin aging and photocarcinogenesis and topical formulations based on nanocarrier systems for skin disorders. It discusses cosmeceuticals, laser, photodynamic therapy, and melatonin-based treatments as important strategies for photoaging management.
M. Vazzana +4 more
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Bipolar Imidazolium-Based Lipid Analogues for Artificial Archaeosomes
Langmuir, 2021Archaeal lipids have harvested biomedical and biotechnological interest because of their ability to form membranes with low permeability and enhanced temperature and pressure stability. Because of problems in isolating archaeal lipids, chemical synthesis appears to be a suitable means of producing model lipids that mimic the biological counterparts ...
Simon Kriegler +4 more
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Archaeobacterial Ether Lipid Liposomes (Archaeosomes) as Novel Vaccine and Drug Delivery Systems
Critical Reviews in Biotechnology, 1999 Liposomes are artificial, spherical, closed vesicles consisting of one or more lipid bilayer(s). Liposomes made from ester phospholipids have been studied extensively over the last 3 decades as artificial membrane models.
G Dennis Sprott +2 more
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Archaeosomes Display Immunoadjuvant Potential for a Vaccine Against Chagas Disease [PDF]
Human Vaccines and Immunotherapeutics, 2013 Archaeosomes (ARC), vesicles made from lipids extracted from Archaea, display strong adjuvant properties. In this study, we evaluated the ability of the highly stable ARC formulated from total polar lipids of a new Halorubrum tebenquichense strain found in Argentinean Patagonia, to act as adjuvant for soluble parasite antigens in developing ...
Ricardo S Corral +2 more
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Archaeosomes as means of nano-drug delivery
Reviews in Medical Microbiology, 2014Archaeosomes are a novel generation of liposomes that are made from polar ether lipids extracted from the Archaea. They have higher stabilities in acidic or alkaline pH, bile salts, high temperatures and against phospholipase, oxidation, chemical and enzymatic hydrolysis in comparison with conventional liposomes.
Eskandar Moghimipour +2 more
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Archaeosome adjuvants: Immunological capabilities and mechanism(s) of action
Vaccine, 2008Archaeosomes (liposomes comprised of glycerolipids of Archaea) constitute potent adjuvants for the induction of Th1, Th2 and CD8(+) T cell responses to the entrapped soluble antigen. Archaeal lipids are uniquely constituted of ether-linked isoprenoid phytanyl cores conferring stability to the membranes. Additionally, varied head groups displayed on the
Lakshmi, Krishnan, G Dennis, Sprott
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Archaeosomes as Self-adjuvanting Delivery Systems for Cancer Vaccines*
Journal of Drug Targeting, 2003Archaeal ether glycerolipid vesicles (archaeosomes) efficiently deliver exogenous antigen for induction of humoral and cell-mediated immunity. Because induction of CD8 cytotoxic T cells is critical for protective vaccination against tumors, we compared the ability of various archaeosome lipid compositions to evoke a strong CD8 CTL response to entrapped
Lakshmi, Krishnan, G, Dennis Sprott
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Synthetic archaeosome adjuvants
2009Taiwan-Canada Bilateral Workshop: Glycosicence Workshop, Taipei, Taiwan, November ...
Whitfield, Dennis M., Sprott, Dennis G.
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In vitro assessment of archaeosome stability for developing oral delivery systems
International Journal of Pharmaceutics, 2000The in vitro stability of archaeosomes made from the total polar lipids of Methanosarcina mazei, Methanobacterium espanolae or Thermoplasma acidophilum, was evaluated under conditions encountered in the human gastrointestinal tract. At acidic pH, multilamellar vesicles (MLV) prepared from T.
Patel, Girishchandra B. +4 more
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