Results 101 to 110 of about 123,827 (273)

Detection of circulating tumor DNA in colorectal cancer patients using a methylation‐specific droplet digital PCR multiplex

open access: yesMolecular Oncology, EarlyView.
We developed a cost‐effective methylation‐specific droplet digital PCR multiplex assay containing tissue‐conserved and tumor‐specific methylation markers. The assay can detect circulating tumor DNA with high accuracy in patients with localized and metastatic colorectal cancer.
Luisa Matos do Canto   +8 more
wiley   +1 more source

Seasonal Forestry Archetype

open access: yesARQ
The Seasonal Forestry Archetype proposes an alternative, community-oriented approach to forestry in Ucayali, integrating wood processing plants with local communities.
Maryhori Quispe Castillo
doaj   +1 more source

Locke's Criterion for the Reality of Ideas: Unambiguous but Untenable [PDF]

open access: yes, 1997
The paper argues against the claim held, e.g., by Leibniz, that Locke employs a double standard for determining whether an object before the mind (i.e., an idea) is real.
de Waal, Cornelis
core  

Transcriptional network analysis of PTEN‐protein‐deficient prostate tumors reveals robust stromal reprogramming and signs of senescent paracrine communication

open access: yesMolecular Oncology, EarlyView.
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice   +16 more
wiley   +1 more source

EDUCATION AS MYTHIC IMAGE [PDF]

open access: yes, 2002
Mythopoetry, the imagistic voice of the muses which manifests in myth and natural poetry, has been invoked as an impression of ideal curriculum with which to cherish intimate, vital experience (and to oppose its exile from educational life).
Nixon, Gregory
core  

Next‐generation proteomics improves lung cancer risk prediction

open access: yesMolecular Oncology, EarlyView.
This is one of very few studies that used prediagnostic blood samples from participants of two large population‐based cohorts. We identified, evaluated, and validated an innovative protein marker model that outperformed an established risk prediction model and criteria employed by low‐dose computed tomography in lung cancer screening trials.
Megha Bhardwaj   +4 more
wiley   +1 more source

Wasserstein Archetypal Analysis

open access: yesApplied Mathematics & Optimization
Archetypal analysis is an unsupervised machine learning method that summarizes data using a convex polytope. In its original formulation, for fixed k, the method finds a convex polytope with k vertices, called archetype points, such that the polytope is contained in the convex hull of the data and the mean squared Euclidean distance between the data ...
Katy Craig   +3 more
openaire   +3 more sources

Archetypes of land transformations and trajectories of ecosystem services in mountains. [ID660] [PDF]

open access: yes, 2019
Based on a synthesis of 51 cases of temporal changes in land use and ecosystem services within mountain landscapes, we analyze how changes in land-use intensity influence the supply of ten key services and we describe six typical archetypes. Our analysis
Locatelli, Bruno
core  

Potential therapeutic targeting of BKCa channels in glioblastoma treatment

open access: yesMolecular Oncology, EarlyView.
This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak   +4 more
wiley   +1 more source

PECULIARITIES OF ARCHETYPES’ REPRODUCTION IN THE TRANSLATION OF AN ARTISTIC WORK

open access: yesІноземна філологія
The article examines the peculiarities of reproduction of archetypes in the translation of an artistic work. The interpretation of the concept of ‘archetype’, its classifi cations and levels of its mental representation in the text are studied herein ...
Mariia Kravtsova
doaj   +1 more source

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