Results 61 to 70 of about 76,245 (285)

Comparing the Performance of NoSQL Approaches for Managing Archetype-Based Electronic Health Record Data

open access: yesPLoS ONE, 2016
This study provides an experimental performance evaluation on population-based queries of NoSQL databases storing archetype-based Electronic Health Record (EHR) data. There are few published studies regarding the performance of persistence mechanisms for
S. M. Freire   +5 more
semanticscholar   +1 more source

Molecular bases of circadian magnesium rhythms across eukaryotes

open access: yesFEBS Letters, EarlyView.
Circadian rhythms in intracellular [Mg2+] exist across eukaryotic kingdoms. Central roles for Mg2+ in metabolism suggest that Mg2+ rhythms could regulate daily cellular energy and metabolism. In this Perspective paper, we propose that ancestral prokaryotic transport proteins could be responsible for mediating Mg2+ rhythms and posit a feedback model ...
Helen K. Feord, Gerben van Ooijen
wiley   +1 more source

Divine marriage and the image of a politician [PDF]

open access: yesZbornik Radova Filozofskog Fakulteta u Prištini, 2014
It is a common place of the contemporary political science that the pattern of the image of a politician contains components based on the archaic cognitive structures. First of all, to such components the archetypes belong.
Šerman Elena M.
doaj   +1 more source

Real‐time assay of ribonucleotide reductase activity with a fluorescent RNA aptamer

open access: yesFEBS Letters, EarlyView.
Ribonucleotide reductases (RNR) synthesize DNA building blocks de novo, making them crucial in DNA replication and drug targeting. FLARE introduces the first single‐tube real‐time coupled RNR assay, which enables isothermal tracking of RNR activity at nanomolar enzyme levels and allows the reconstruction of allosteric regulatory patterns and rapid ...
Jacopo De Capitani   +4 more
wiley   +1 more source

Efficient propagation of archetype JC polyomavirus in COS-7 cells: evaluation of rearrangements within the NCCR structural organization after transfection

open access: yesArchives of Virology, 2017
John Cunningham virus (JCPyV) is an ubiquitous human pathogen that causes disease in immunocompromised patients. The JCPyV genome is composed of an early region and a late region, which are physically separated by the non-coding control region (NCCR ...
C. Prezioso   +7 more
semanticscholar   +1 more source

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

open access: yesFEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe   +3 more
wiley   +1 more source

Directional Applicability Analysis of Albedo Retrieval Using Prior BRDF Knowledge

open access: yesRemote Sensing
Surface albedo measures the proportion of incoming solar radiation reflected by the Earth’s surface. Accurate albedo retrieval from remote sensing data usually requires sufficient multi-angular observations to account for the surface reflectance ...
Hu Zhang   +9 more
doaj   +1 more source

Comparing self‐reported race and genetic ancestry for identifying potential differentially methylated sites in endometrial cancer: insights from African ancestry proportions using machine learning models

open access: yesMolecular Oncology, EarlyView.
Integrating ancestry, differential methylation analysis, and machine learning, we identified robust epigenetic signature genes (ESGs) and Core‐ESGs in Black and White women with endometrial cancer. Core‐ESGs (namely APOBEC1 and PLEKHG5) methylation levels were significantly associated with survival, with tumors from high African ancestry (THA) showing ...
Huma Asif, J. Julie Kim
wiley   +1 more source

Climate-Adaptive Archetypes of Vernacular Villages and Their Application in Public Building Design: A Case Study of a Visitor Center in Chaoshan, China

open access: yesBuildings
The Sixth Assessment Report of the IPCC highlights that global surface temperatures have risen by 1.1 °C above pre-industrial levels, with a marked increase in the frequency and intensity of extreme heat events in hot–humid regions.
Fengdeng Wan   +4 more
doaj   +1 more source

Home - About - Disclaimer - Privacy