Results 71 to 80 of about 123,827 (273)

In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS

FEBS Letters, EarlyView.
We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka, Yuxi Liu, Stefano Maggi, Debnath Ghosal, Jue Wang, Prashant P. Damke, Stephen D. Carter, Wei Zhao, Sukhithasri Vijayrajratnam, Joseph P. Vogel, Carrie L. Shaffer, Grant J. Jensen   +11 more
wiley   +1 more source

Archetypes

Archetypes are mental structures that are shared among members of a species. They are thought to be innate rather than learnt, and help individuals make sense of and decide what to do about the world.
KOH, Ivy H. Y., LI, Norman P.
  +6 more sources

Directional Applicability Analysis of Albedo Retrieval Using Prior BRDF Knowledge

Remote Sensing
Surface albedo measures the proportion of incoming solar radiation reflected by the Earth’s surface. Accurate albedo retrieval from remote sensing data usually requires sufficient multi-angular observations to account for the surface reflectance ...
Hu Zhang, Qianrui Xi, Junqin Xie, Xiaoning Zhang, Lei Chen, Yi Lian, Hongtao Cao, Yan Liu, Lei Cui, Yadong Dong   +9 more
doaj   +1 more source

Cell wall target fragment discovery using a low‐cost, minimal fragment library

FEBS Letters, EarlyView.
LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan, Mathew Stanley, Olawale Raimi, Andrew T. Ferenbach, Helge C Dorfmueller, Daan M. F. van Aalten   +5 more
wiley   +1 more source

Creolization and the collective unconscious: locating the originality of art in Wilson Harris' Jonestown, The Mask of the Beggar and The Ghost of Memory [PDF]

, 2008
Alongside the essays and fiction of Edouard Glissant, Wilson Harris's writings stand as one of the most important contributions to Caribbean creolization theory.
Burns, L.
core  

Stigmergy-based modeling to discover urban activity patterns from positioning data

, 2019
Positioning data offer a remarkable source of information to analyze crowds urban dynamics. However, discovering urban activity patterns from the emergent behavior of crowds involves complex system modeling.
Alfeo, Antonio L., Cimino, Mario G. C. A., Egidi, Sara, Lepri, Bruno, Pentland, Alex, Vaglini, Gigliola   +5 more
core   +1 more source

Paraneoplastic Lupus Nephritis in a Child With Neuroblastoma Recurrence

Pediatric Blood &Cancer, EarlyView.
Gabriele Mortari, Caterina Costagliola, Marta Nebiolo, Francesca Parisi, Martina Morini, Katia Mazzocco, Gabriele Gaggero, Stefano Volpi, Stefania Sorrentino, Virginia Livellara   +9 more
wiley   +1 more source

Inhibiting stearoyl‐CoA desaturase suppresses bone metastatic prostate cancer by modulating cellular stress, mTOR signaling, and DNA damage response

FEBS Letters, EarlyView.
Bone metastasis in prostate cancer (PCa) patients is a clinical hurdle due to the poor understanding of the supportive bone microenvironment. Here, we identify stearoyl‐CoA desaturase (SCD) as a tumor‐promoting enzyme and potential therapeutic target in bone metastatic PCa.
Alexis Wilson, Mackenzie K Herroon, Shane Mecca, Laimar C Garmo, Jacob Lindquist, Shrila Rajendran, Steve M. Patrick, Izabela Podgorski   +7 more
wiley   +1 more source

Climate-Adaptive Archetypes of Vernacular Villages and Their Application in Public Building Design: A Case Study of a Visitor Center in Chaoshan, China

Buildings
The Sixth Assessment Report of the IPCC highlights that global surface temperatures have risen by 1.1 °C above pre-industrial levels, with a marked increase in the frequency and intensity of extreme heat events in hot–humid regions.
Fengdeng Wan, Ziqiao Li, Huazhao Li, Li Li, Xiaomiao Xiao   +4 more
doaj   +1 more source

Legal Archetypes and Metadata Collection [PDF]

, 2017
In discussions of state surveillance, the values of privacy and security are often set against one another, and people often ask whether privacy is more important than national security.2 I will argue that in one sense privacy is more important than ...
Rubel, Alan
core