Results 61 to 70 of about 134,557 (313)
Cryptochrome and PAS/LOV proteins play intricate roles in circadian clocks where they act as both sensors and mediators of protein–protein interactions. Their ubiquitous presence in signaling networks has positioned them as targets for small‐molecule therapeutics. This review provides a structural introduction to these protein families.
Eric D. Brinckman +2 more
wiley +1 more source
In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS
We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka +11 more
wiley +1 more source
Analysis of the Application of Universal Design Standards to Interior-Architecture Design [PDF]
A lot of research shows the findings of cases of public facilities that are not accessible to people with disabilities and see the importance of a design especially in the field of architecture-interior that is able to produce a user-friendly and barrier-
Cardiah, T. (Tita ) +4 more
core
Selected Aspects of the Tourist Space of the Lublin Region (Case Study) [PDF]
The article presents the results of studies on the tourist space of the Lublin Region conducted so far by employees of the Department of Regional Geography and Tourism at the Faculty of Earth Sciences and Spatial Management of the Maria Curie-Skłodowska ...
Brzezińska-Wójcik, Teresa +5 more
core +2 more sources
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee +3 more
wiley +1 more source
The article analyzes the experience of foreign countries in the field of architectural accessibility for people with limited mobility and the possibilities of its adaptation in Ukraine.
Svitlana Surgova, Olena Faichuk
doaj +1 more source
Structural biology of ferritin nanocages
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley +1 more source
Acessibilidade aos serviços de saúde: uma análise a partir da Atenção Básica em Pernambuco
Analisou-se a acessibilidade aos serviços de saúde de Atenção Básica em Pernambuco e os aspectos que favorecem ou dificultam a entrada e a permanência do usuário no sistema de saúde.
Maria do Socorro Veloso de Albuquerque +4 more
doaj +1 more source
Effective workplaces – bridging the gap between architectural research and design practice. [PDF]
Architectural researchers and design practitioners mostly segregate in distinct communities with hardly any overlap, collaboration or exchange of ideas.
Budgen, A +4 more
core
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley +1 more source

