Results 91 to 100 of about 705,550 (337)

Bioengineering facets of the tumor microenvironment in 3D tumor models: insights into cellular, biophysical and biochemical interactions

FEBS Open Bio, EarlyView.
The tumor microenvironment is a dynamic, multifaceted complex system of interdependent cellular, biochemical, and biophysical components. Three‐dimensional in vitro models of the tumor microenvironment enable a better understanding of these interactions and their impact on cancer progression and therapeutic resistance.
Salma T. Rafik, Deniz Bakkalci, Alexander J. MacRobert, Umber Cheema   +3 more
wiley   +1 more source

Potential Assessment and Community Environment Support Strategies for Social Interaction, Based on the Spatiotemporal Behavior of Accompanying Elderly Migrants: A Case Study in Hangzhou

Land
With the growing trend of population mobility and the aging process in China, a significant number of accompanying elderly migrants have moved to major cities.
Zhi Qiu, Bo Jin, Binwei Yun, Zhu Wang, Xincheng Pu   +4 more
doaj   +1 more source

A Qualitative Method for Assessing the Impact of ICT on the Architectural Design Process [PDF]

, 2013
During the last thirty years or so, we have witnessed tremendous developments in information and communication technology (ICT). Computer processing power doubles each 18 months, as Gordon Moore predicted during the mid-1960s.
Ganah, Abdulkadir, Kamara, John
core  

Matrix: a complex amalgam of structures and functions in tumor microenvironment

FEBS Open Bio, EarlyView.
The matrix is a dynamic, intricate three‐dimensional mesh of biomolecules with both structural and functional properties. This review deals with the complexity of this ‘molecular amalgam’ in the tumor microenvironment and highlights its importance in the maintenance and evolution of tumors by describing certain matrix biomolecules, such as ...
Spyros S. Skandalis, Evgenia Tsoukala, Theodora D. Sarantopoulou, Maria‐Elpida Christopoulou   +3 more
wiley   +1 more source

NMR screening of low molecular weight inhibitors targeting the papain‐like protease (PLPro) of SARS‐CoV‐2

FEBS Open Bio, EarlyView.
Papain‐like protease from SARS‐CoV‐2 plays an important role in the cleavage of the viral polyproteins and in the suppression of the host's immune response. Here, we present the results of an NMR screening study. We identified 86 binding compounds, of which five candidates were chosen for in‐depth analysis.
Dennis J. Pyper, Sridhar Sreeramulu, Benjamin T. Lanham, Elizabeth M. Engle, David Fushman, Harald Schwalbe   +5 more
wiley   +1 more source

Effective workplaces – bridging the gap between architectural research and design practice. [PDF]

, 2007
Architectural researchers and design practitioners mostly segregate in distinct communities with hardly any overlap, collaboration or exchange of ideas.
Budgen, A, Lonsdale, N, Penn, A, Sailer, K, Turner, A   +4 more
core  

Transcriptional regulation of neuropeptide receptors underlies context‐dependent adaptation in Drosophila melanogaster

FEBS Open Bio, EarlyView.
Under environmental changes, the expression level of neuropeptide (NP) and neuropeptide receptor (NPR) genes changes to confer context‐dependent adaptation to the model organism Drosophila melanogaster. Through finding more regulatory elements in the NPR genes in comparison with their ligands (NPs), we found that NPR‐biased transcriptional regulation ...
SeungHeui Ryu, Yanan Wei, Zekun Wu, Tianmu Zhang, DoHoon Lee, Hadi Najafi, Woo Jae Kim   +6 more
wiley   +1 more source

Building Engineering Feasibility Study: Herreshoff Marine Museum [PDF]

, 2014
Our design team was supplied with a dozen architectural designs from the students of the Roger Williams University Architectural School. After discussing the strengths and weaknesses of each our team was able to narrow our choices down to one base design
Brunnhoeffer, Gilbert, Camiolo, Vanessa, Devereaux, Janelle, Newton, Kayla, Robinson, Arnold, Ruocco, Anthony, Turner, Zach   +6 more
core   +1 more source

Report on the 2nd MObility for Vesicle research in Europe (MOVE) symposium—2024

FEBS Open Bio, EarlyView.
The 2nd MObility for Vesicle research in Europe (MOVE) Symposium in Belgrade brought over 280 attendees from 28 countries to advance extracellular vesicle (EV) research. Featuring keynotes, presentations, and industry sessions, it covered EV biogenesis, biomarkers, therapies, and manufacturing.
Dorival Mendes Rodrigues‐Junior, Michaela Kocholata, Marilena E. Lekka, Olga Janouskova, Moran Yadid, Maja Kosanovic   +5 more
wiley   +1 more source

The musealisation of the artist's house as architectural project [PDF]

, 2011
Artist’s houses that are opened to the public as museums shift from a private and everyday to a semi-public and institutional functioning. This transformation of an artist’s house into a house-museum might appear as a mere legal issue or as a matter of ...
Liefooghe, Maarten
core