Results 71 to 80 of about 428,058 (275)

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

open access: yesFEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee   +3 more
wiley   +1 more source

Transforming a Cantilever with Fixed Joints into Trussed Configurations: A Case Study in Creative Design Thinking & Prototyping

open access: yesArchitecture, Civil Engineering, Environment
In the design of structures, joint design significantly influences aesthetics, structural performance, tectonics, and member geometry. In this study, a Y-shaped, polyhedral cantilever with fixed joints was transformed into five different trussed ...
Filz Günther H.   +3 more
doaj   +1 more source

Structural biology of ferritin nanocages

open access: yesFEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source

The place and the project. The Fornace Morandi along the Brenta River: project proposals for a new park in Noventa Padovana, Italy

open access: yesProceedings of the International Conference of Contemporary Affairs in Architecture and Urbanism-ICCAUA, 2023
Noventa Padovana is a town in the province of Padua, located a short distance from Venice. This contribution considers the wide area, today in degraded conditions, including the ruins of a kiln for the production of tiles and bricks which was built at ...
Enrico Pietrogrande   +1 more
doaj   +1 more source

Spatial planning and architectural innovation in the Roman town of Ocriculum. [PDF]

open access: yes, 2018
The Roman settlement of Ocriculum (Otricoli, TR - Umbria), built on a tufa slope between the Tiber valley to the north and the San Vittore valley to the south, was established on massive substructures, which allowed the exploitation of a larger area ...
ANTONELLI, GIACOMO
core   +1 more source

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

open access: yesFEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Assessing The Economic Feasibility of Applying Integrated Photo Voltaic (BIPV) System in Residential Buildings in Egypt

open access: yesJournal of Architecture, Art & Humanistic Science
Nowadays, the human need for electrical energy is escalating due to the growing demand of modern life applications, however, the increasing demand for fossil fuel sources for electricity production has led to the climate changes.
Prof. Safaa Mahmoud Issa Professor Architectural Department – Faculty of Engineering – Menoufia University   +1 more
doaj   +1 more source

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

open access: yesFEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura   +2 more
wiley   +1 more source

DEVELOPMENT AND IMPLEMENTATION OF INNOVATIVE EDUCATIONAL MODULES ON ARCHITECTURAL PHOTOGRAMMETRY FOR BACHELOR’S DEGREE CURRICULA IN ARCHITECTURE [PDF]

open access: yesThe International Archives of the Photogrammetry, Remote Sensing and Spatial Information Sciences, 2019
Modern specialists in the field of architecture work exclusively in three-dimensional space. At the same time, their training completely ignores the state-of-the-art technologies associated with obtaining three-dimensional models of engineering ...
R. Shults
doaj   +1 more source

Architecture Engineering Developments

open access: yes, 2016
This presentation will demonstrate some of the buildings, structural frames, mechanical systems, and infrastructure I worked on for my Architectural Engineering Senior Design projects. The first included an 80-story skyscraper and plaza. For the project, the leaning design had to be resolved architecturally with complete and detailed renderings of the ...
Drake, Paul   +9 more
openaire   +2 more sources

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