Results 141 to 150 of about 582,222 (384)

Identification of inhibitors of the Salmonella FraB deglycase, a drug target

open access: yesFEBS Open Bio, EarlyView.
A high‐throughput screen was used to identify inhibitors of Salmonella FraB, a drug target. Characterization of top hits (identified after an additional counter screen) revealed that some triazolidines, thiadiazolidines, and triazolothiadiazoles are mixed‐type inhibitors of FraB.
Jamison D. Law   +6 more
wiley   +1 more source

Arctic system on trajectory to new state [PDF]

open access: yes, 2005
The Arctic system is moving toward a new state that falls outside the envelope of glacial-interglacial fluctuations that prevailed during recent Earth history.
Benner, Ronald   +19 more
core   +2 more sources

Characterisation of the role played by ELMO1, GPR141 and the intergenic polymorphism rs918980 in Fuchs' dystrophy in the Indian population

open access: yesFEBS Open Bio, EarlyView.
This study reports the upregulation of ELMO1 and GPR141 in human Fuchs' endothelial corneal dystrophy (FECD) corneal endothelium and ultraviolet A‐induced FECD mice model. A genetic association of an intergenic single nucleotide polymorphism rs918980 present between both genes is observed with FECD in the Indian population.
Susmita Sharma   +3 more
wiley   +1 more source

An Arctic Railroad [PDF]

open access: yesScientific American, 1898
n ...
openaire   +2 more sources

Mapping Hsp104 interactions using cross‐linking mass spectrometry

open access: yesFEBS Open Bio, EarlyView.
This study examines how cross‐linking mass spectrometry can be utilized to analyze ATP‐induced conformational changes in Hsp104 and its interactions with substrates. We developed an analytical pipeline to distinguish between intra‐ and inter‐subunit contacts within the hexameric homo‐oligomer and discovered contacts between Hsp104 and a selected ...
Kinga Westphal   +3 more
wiley   +1 more source

An analysis of potential conflict zones in the arctic region [PDF]

open access: yesarXiv, 2016
As a result of the climate change the situation in Arctic area leads to several important consequences. On the one hand, oil and gas resources can be exploited much easier than before. Thus, one can already observe discussions on disputed shelf zones where the deposits are located.
arxiv  

Conditions of the alimentation and the variability of glaciers of the Severnaya Zemlya Archipelago from observations of 2014–2015

open access: yesЛëд и снег, 2016
Glaciological investigations on the Severnaya Zemlya archipelago were resumed in 2013 when a new research station «Ice base Cape Baranova» had been organized by Arctic and Antarctic Research Institute in the North-West of the Island Bolshevik.
D. Yu. Bolshiyanov   +6 more
doaj   +1 more source

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