Results 141 to 150 of about 680,036 (364)
Thrombolytic proteins profiling: High‐throughput activity, selectivity, and resistance assays
FEBS Open Bio, EarlyView.We present optimized biochemical protocols for evaluating thrombolytic proteins, enabling rapid and robust screening of enzymatic activity, inhibition resistance, and fibrin affinity, stimulation, and selectivity. The outcome translates to key clinical indicators such as biological half‐life and bleeding risk. These assays streamline the development of
Martin Toul +3 more
wiley +1 more source
Financing of low resource intensity technology of Arctic industrial enterprises [PDF]
, 2019 Vladimir Zharov +1 more
openalex +1 more source
2019 State-of-the-Science of Dispersants and Dispersed Oil (DDO) in U.S. Arctic Waters: Public Health and Food Safety [PDF]
, 2019 Chemical dispersants were employed on an unprecedented scale during the Deepwater Horizon oil spill in the Gulf of Mexico, and could be a response option should a large spill occur in Arctic waters. The use of dispersants in response to that spill raised
Coastal Response Research Center
core +2 more sources
FEBS Open Bio, EarlyView.Chemotherapies such as doxorubicin can have toxic effects on healthy cardiovascular/heart tissue. Following up on a doxorubicin toxicity study in mice without tumors where nitrate water was cardioprotective (lessened toxicity), this study with tumor‐bearing mice undergoing doxorubicin treatment showed no negative effect of nitrate and nitrite on drug ...
Rama D. Yammani +7 more
wiley +1 more source
FEBS Open Bio, EarlyView.Excess Ca2+ ions activate the Calcium‐Sensing Receptor (CaSR), which subsequently drives the uptake of excess inorganic phosphate (Pi) via the Pi transporter (Pit−1) in chondrocytes. This mechanism causes a toxic increase in intracellular Pi concentration, ultimately leading to chondrocyte apoptosis and pathological mineralization. Excess extracellular
Sachie Nakatani +7 more
wiley +1 more source
Interactive tables in the wild - visitor experiences with multi-touch tables in the Arctic exhibit at the Vancouver Aquarium [PDF]
, 2015 Funding: Alberta Innovates–Technology Futures (Alberta Ingenuity & iCORE), CFI, NSERC, and SMART Technologies.This report describes and discusses the findings from a field study that was conducted at the Vancouver Aquarium to investigate how visitors ...
Carpendale, Sheelagh, Hinrichs, Uta
core
FEBS Open Bio, EarlyView.This research protocol outlines a workflow for nuclear magnetic resonance (NMR)‐based metabolomics in the agri‐food sector. Using two case studies—strawberry leaves (solid matrix) and wine (liquid matrix)—it details the procedures for sample preparation, data acquisition, and processing.
Andrea Fernández‐Veloso +4 more
wiley +1 more source
Significant parameters of mining properties in arctic and subarctic areas of North America [PDF]
, 1983 Editors: Bruce W. Campbell and John J. DiMarchiThis paper is a review of those factors unique to mining in the Arctic and subarctic. The information was developed from an exhaustive Literature search and personal visits to several northern mines in ...
Hackney, D.A., Lambert, C.
core
DDX3X induces mesenchymal transition of endothelial cells by disrupting BMPR2 signaling
FEBS Open Bio, EarlyView.Elevated DDX3X expression led to downregulation of BMPR2, a key regulator of endothelial homeostasis and function. Our co‐immunoprecipitation assays further demonstrated a molecular interaction between DDX3X and BMPR2. Notably, DDX3X promoted lysosomal degradation of BMPR2, thereby impairing its downstream signaling and facilitating endothelial‐to ...
Yu Zhang +7 more
wiley +1 more source
Co-Production of Knowledge in Arctic Research: Reconsidering and Reorienting Amidst the Navigating the New Arctic Initiative [PDF]
, 2022 Matthew L. Druckenmiller
openalex +1 more source