Results 71 to 80 of about 827,682 (359)

The inhibitory SAPS3–AMPK interaction detected in HEK293 cells is not detectable in muscle or liver from humans or mice

FEBS Letters, EarlyView.
This study challenges the idea that Sit4‐associated protein subunit 3 (SAPS3) inhibits the energy‐sensing enzyme AMP‐activated protein kinase (AMPK) in muscle and liver tissue. Although SAPS3 interacts with AMPK in cultured cells, we found no such interaction in human or mouse tissues subjected to fasting, exercise, or a high‐fat diet.
Jesper B. Birk, Maria A. Møller, Jørgen F.P. Wojtaszewski, Rasmus Kjøbsted   +3 more
wiley   +1 more source

The Influence of Above-Ground Herbivory on the Response of Arctic Soil Methanotrophs to Increasing CH₄ Concentrations and Temperatures

Microorganisms, 2021
Rising temperatures in the Arctic affect soil microorganisms, herbivores, and peatland vegetation, thus directly and indirectly influencing microbial CH4 production.
Edda M. Rainer, Christophe V. W. Seppey, Caroline Hammer, Mette M. Svenning, Alexander T. Tveit   +4 more
doaj   +1 more source

Flux of nutrients from Russian rivers to the Arctic Ocean: Can we establish a baseline against which to judge future changes? [PDF]

, 2000
Climate models predict significant warming in the Arctic in the 21st century, which will impact the functioning of terrestrial and aquatic ecosystems as well as alter land‐ocean interactions in the Arctic.
Gordeev, V. V., Holmes, R. M., Lammers, Richard B., Meybeck, M., Peterson, B. J., Vorosmarty, Charles J., Zhulidov, A. V.   +6 more
core   +1 more source

Peptide‐based ligand antagonists block a Vibrio cholerae adhesin

FEBS Letters, EarlyView.
The structure of a peptide‐binding domain of the Vibrio cholerae adhesin FrhA was solved by X‐ray crystallography, revealing how the inhibitory peptide AGYTD binds tightly at its Ca2+‐coordinated pocket. Structure‐guided design incorporating D‐amino acids enhanced binding affinity, providing a foundation for developing anti‐adhesion therapeutics ...
Mingyu Wang, Grace Du, Charity Yongo‐Luwawa, Angelina Lu, Brett Kinrade, Kim Munro, Karl E. Klose, William D. Lubell, Peter Davies, Shuaiqi Guo   +9 more
wiley   +1 more source

Persistent pain associated with socioeconomic and personal factors in a Sami and Non-Sami population in Norway: an analysis of SAMINOR 2 survey data

International Journal of Circumpolar Health, 2020
In international studies, higher prevalence of persistent pain has been reported in indigenous populations compared to majority populations. The present study aimed to determine the prevalence of persistent pain within a Sami and a non-Sami population in
Elin Damsgård, Gyrd Thrane, Nils Fleten, Johan Bagge, Tore Sørlie, Audny Anke, Ann-Ragnhild Broderstad   +6 more
doaj   +1 more source

Microsatellite loci among Alaskan rabies hosts: Arctic and red fox [PDF]

, 2012
Little is known about the population dynamics between Arctic and red foxes in Alaska and consequences for rabies ecology. Both species carry different variants of rabies and inhabit different environments.
Renshaw, Ben
core  

The influence of Arctic amplification on mid-latitude summer circulation

Nature Communications, 2018
Accelerated warming in the Arctic, as compared to the rest of the globe, might have profound impacts on mid-latitude weather. Most studies analyzing Arctic links to mid-latitude weather focused on winter, yet recent summers have seen strong reductions in
D. Coumou, D. Coumou, G. D. Capua, G. D. Capua, S. Vavrus, Lei Wang, S. Wang   +6 more
semanticscholar   +1 more source

Tonic signaling of the B‐cell antigen‐specific receptor is a common functional hallmark in chronic lymphocytic leukemia cell phosphoproteomes at early disease stages

Molecular Oncology, EarlyView.
B‐cell chronic lymphocytic leukemia (B‐CLL) and monoclonal B‐cell lymphocytosis (MBL) show altered proteomes and phosphoproteomes, analyzed using mass spectrometry, protein microarrays, and western blotting. Identifying 2970 proteins and 316 phosphoproteins, including 55 novel phosphopeptides, we reveal BCR and NF‐kβ/STAT3 signaling in disease ...
Paula Díez, Pablo Juanes‐Velasco, Marina L. García‐Vaquero, Conrad Droste, Alicia Landeira‐Viñuela, Miguel Alcoceba, Helena Fidalgo‐Gómez, Sara Misiego‐Herrero, Almudena Navarro‐Bailón, Mónica Baile, José M. Bastida, Jose Manuel Sanchez‐Santos, Rafael Góngora, Julia Almeida, Marcos Gonzalez‐Diaz, Alberto Orfao, Javier De Las Rivas, Manuel Fuentes   +17 more
wiley   +1 more source

Evolution of climate, glaciation and subglacial environments of Antarctica from the deep ice core and Lake Vostok water sample studies (Key results of implementation of the Russian Science Foundation project, 2014–2016)

Лëд и снег, 2017
Work on the project focused on the following five areas: 1)  field works in Antarctica at Vostok and Concordia stations; 2)  experimental and theoretical studies in the field of ice core and paleoclimate research; 3) experimental and theoretical works ...
V. Ya. Lipenkov, A. A. Ekaykin, I. A. Alekhina, Yu. A. Shibaev, A. V. Kozachek, D. O. Vladimirova, N. I. Vasilev, A. V. Preobrazhenskaya   +7 more
doaj   +1 more source

Informativeness (information-bearing) of hydrometeorological and astrogeophysical factors in the problem of describing interannual fluctuations of the Greenland Sea ice coverage

Лëд и снег, 2021
The interannual changes in ice coverage in the Greenland Sea for the winter (December–April), spring (May– June), summer (July–September), and autumn (October–November) seasons for the period 1950-2018 are considered.
N. A. Viazigina, L. A. Timokhov, E. S. Egorova, A. V. Yulin   +3 more
doaj   +1 more source