Results 71 to 80 of about 336,642 (296)

Arctic Environmental Protection Strategy (AEPS) Ministerial Meeting in Alta, Norway. 1997 [PDF]

, 1997
Arctic Environmental Protection Strategy (AEPS) is the predecessor of the Arctic Council, established in Rovaniemi Finland in 1991.
Arctic Council, -
core   +1 more source

Development of the technology of a new flour culinary fish product enriched with iodine of the White Sea kelp

Vestnik MGTU
The range of fish culinary products has been selected based on the analysis of consumer motivation in Murmansk and current trends in the development of the regional fish culinary products market.
Savkina K. N., Cshetinsky V. V., Tihonova P. A., Shokina Yu. V.   +3 more
doaj   +1 more source

Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization

Molecular Oncology, EarlyView.
In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu, Nicolas J. Niklaus, Anna M. Schläfli, Igor Tokarchuk, Magali Humbert, Federico La Manna, Bich Vu, David Maul, Ramin Radpour, Marianna Kruithof‐de Julio, Inti Zlobec, Jörn Dengjel, Bruce E. Torbett, Mario P. Tschan   +13 more
wiley   +1 more source

Evolution of climate, glaciation and subglacial environments of Antarctica from the deep ice core and Lake Vostok water sample studies (Key results of implementation of the Russian Science Foundation project, 2014–2016)

Лëд и снег, 2017
Work on the project focused on the following five areas: 1)  field works in Antarctica at Vostok and Concordia stations; 2)  experimental and theoretical studies in the field of ice core and paleoclimate research; 3) experimental and theoretical works ...
V. Ya. Lipenkov, A. A. Ekaykin, I. A. Alekhina, Yu. A. Shibaev, A. V. Kozachek, D. O. Vladimirova, N. I. Vasilev, A. V. Preobrazhenskaya   +7 more
doaj   +1 more source

Arctic and Sub-Arctic Bees

Nature, 1898
OF the wild bees of Alaska nothing is known, except that several species of humble-bees (Bombus) are common. Consequently, when Mr. Trevor Kincaid wrote me last year that he was going to Alaska, and would collect bees, I was expecting to see, on his return, quite a new bee-fauna.
openaire   +1 more source

PAK1 activation drives divergent resistance mechanisms to aromatase inhibition and tamoxifen in a luminal: A breast cancer model

Molecular Oncology, EarlyView.
Breast cancer remains a major cause of cancer death in women, frequently developing endocrine therapy resistance. This study demonstrates that upregulated p21‐activated kinase 1 (PAK1) activity drives resistance to tamoxifen and long‐term estrogen deprivation in ER+ breast cancer models.
Luisa Schwarzmüller, Janina Müller, Efstathios‐Iason Vlachavas, Lukas Beumers, Lena Fleischhacker, Sara Burmester, Angelika Wörner, Sabine Karolus, Dominic Helm, Cindy Körner, Stefan Wiemann   +10 more
wiley   +1 more source

Declaration on Establishment of The Arctic Council (The Ottawa Declaration) - 1996 [PDF]

, 1996
The declaration of the establishment of the Arctic ...
Arctic Council, -
core   +1 more source

Pharmacological chromatin remodeling enhances response to estrogen therapy in ER+ breast cancer

Molecular Oncology, EarlyView.
Estrogen therapy elicits clinical benefit in ~ 30% of patients with endocrine‐resistant estrogen receptor (ER)‐positive breast cancer. Based on findings that ER transcriptional activation underlies response to estrogen therapy, we tested the effects of epigenetic dysregulation via pharmacological inhibition of histone deacetylases (HDACi).
Anneka L. Johnson Thomas, Barbara Karakyriakou, Patricia C. Muskus, Alyssa M. Roberts, Justin Rendleman, Alexa Warren, Hanxu Lu, Kimberly A. Birmingham, Malone K. Friedman, Abigail E. Goen, Huijuan Yang, Owen M. Wilkins, Fred W. Kolling, Eugene Demidenko, Julie M. Jorns, Brock C. Christensen, Todd W. Miller   +16 more
wiley   +1 more source

Somatostatin receptor 4 (SSTR4) is a tumor suppressor in cutaneous and head & neck squamous cell carcinomas

Molecular Oncology, EarlyView.
This study identifies somatostatin receptor 4 (Sstr4) as a critical tumor suppressor against skin and head/neck cancers (HNSCC, cSCC, and BCC). The loss of Sstr4 removes a check on cell growth, causing hyperactivation of the MAPK‐ERK signaling pathway (↑).
Ali Taqvi, Tuan Khang Huynh, Adway Kadam, Zahra Kardan, Yue Yan, Amina Jamal Laham, Sampath Kumar Loganathan   +6 more
wiley   +1 more source

Development of automated system for receiving and analysing telemetry data from small spacecrafts [PDF]

E3S Web of Conferences
The system presented in the study is designed to increase the share of automation in the process of interaction with small spacecraft (SSС) at all stages of operation.
Aleshko Roman, Gordeychik Alexander, Berezovsky Vladimir, Shoshina Ksenia   +3 more
doaj   +1 more source