Results 81 to 90 of about 819,301 (403)
The Useless Arctic: Exploiting Nature in the Arctic in the 1870s
Nordlit, 2015 <p align="LEFT">What is the discursive genealogy of an ecological approach to the Arctic? Building on distinctions suggested by Francis Spufford and Gísli Pálsson, this article examines a specific juncture in the history of European–Arctic interaction – the reception of the Austro-Hungarian Arctic Expedition in 1874 – and traces the potential for
Spring, Ulrike, Schimanski, Johan Henrik
openaire +8 more sources
Science of The Total Environment, 2022 Anthropogenic mercury (Hg) undergoes long-range transport to the Arctic where some of it is transformed into methylmercury (MeHg), potentially leading to high exposure in some Arctic inhabitants and wildlife. The environmental exposure of Hg is determined not just by the amount of Hg entering the Arctic, but also by biogeochemical and ecological ...
Jonsson, Sofi +10 more
openaire +6 more sources
Cancer cell death induced by the NAD antimetabolite Vacor discloses the antitumor potential of SARM1
FEBS Letters, EarlyView.Vacor, a compound converted into the toxic metabolite Vacor adenine dinucleotide (VAD) by the nicotinamide salvage pathway enzymes NAMPT and NMNAT2, exhibits antitumor activity by inducing rapid and complete NAD depletion. We report that Vacor toxicity is limited to cell lines expressing high levels of SARM1, a NAD glycohydrolase.
Giuseppe Ranieri +5 more
wiley +1 more source
Social Indicators for Arctic Mining [PDF]
, 2011 This paper reviews and assesses the state of the data to describe and monitor mining trends in the pan-Arctic. It constructs a mining index and discusses its value as a social impact indicator and discusses drivers of change in Arctic mining.
Crow, Andrew +4 more
core
FEBS Letters, EarlyView.Angiotensin II (AngII), a neuropeptide, interacts with amyloid‐β (Aβ), a key player in Alzheimer's disease. This study reveals that AngII reduces Aβ aggregation and membrane disruption in vitro. Biophysical assays and molecular modeling suggest AngII binds disordered Aβ forms, potentially modulating early amyloidogenic events and contributing to ...
Mohsen Habibnia +5 more
wiley +1 more source
Frontiers in NeuroanatomyFor most non-diving mammals, lack of O2 (hypoxia) has detrimental effects on brain function. Seals, however, display a series of systemic, cellular, and molecular adaptations that enable them to tolerate repeated episodes of severe hypoxia.
Chiara Ciccone +7 more
doaj +1 more source
Phytoplankton dynamics in a changing Arctic Ocean
Nature Climate Change, 2020 Changes in the Arctic atmosphere, cryosphere and Ocean are drastically altering the dynamics of phytoplankton, the base of marine ecosystems. This Review addresses four major complementary questions of ongoing Arctic Ocean changes and associated impacts ...
M. Ardyna, K. Arrigo
semanticscholar +1 more source
Microsatellite loci among Alaskan rabies hosts: Arctic and red fox [PDF]
, 2012 Little is known about the population dynamics between Arctic and red foxes in Alaska and consequences for rabies ecology. Both species carry different variants of rabies and inhabit different environments.
Renshaw, Ben
core
The impact of Arctic sea ice on the Arctic energy budget and on the climate of the Northern mid-latitudes [PDF]
, 2012 The atmospheric general circulation model EC-EARTH-IFS has been applied to investigate the influence of both a reduced and a removed Arctic sea ice cover on the Arctic energy budget and on the climate of the Northern mid-latitudes.
McGrath, R., Semmler, T., Wang, S.
core +1 more source
Molecular Oncology, EarlyView.B‐cell chronic lymphocytic leukemia (B‐CLL) and monoclonal B‐cell lymphocytosis (MBL) show altered proteomes and phosphoproteomes, analyzed using mass spectrometry, protein microarrays, and western blotting. Identifying 2970 proteins and 316 phosphoproteins, including 55 novel phosphopeptides, we reveal BCR and NF‐kβ/STAT3 signaling in disease ...
Paula Díez +17 more
wiley +1 more source