Results 41 to 50 of about 14,201 (262)
Revista Brasileira de Política Internacional, 2023 The effects of climate change over the Arctic region have attracted manifold interests in the last decades from several state and non-state actors. Due to a flawed institutional capacity to promote a multi-stakeholder approach in Arctic affairs, the main
GAO Fei +2 more
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The PI3Kδ inhibitor roginolisib (IOA‐244) preserves T‐cell function and activity
Molecular Oncology, EarlyView.Identification of novel PI3K inhibitors with limited immune‐related adverse effects is highly sought after. We found that roginolisib and idelalisib inhibit chronic lymphocytic leukemia (CLL) cells and Treg suppressive functions to similar extents, but roginolisib affects cytotoxic T‐cell function and promotion of pro‐inflammatory T helper subsets to a
Elise Solli +7 more
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Arktisk Råd – et mellemfolkeligt samarbejde
Internasjonal PolitikkForud for Arktisk Råds tilblivelse i 1996 foregik der et omfattende arbejde mellem staterne, og ikke mindst af de arktiske oprindelige folk. Inuit Circumpolar Council (ICC), som repræsenterer Inuit i Kalaallit Nunaat (Grønland), Canada, Alaska og ...
Sara Olsvig
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Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
Molecular Oncology, EarlyView.This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
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Har Arktisk råd noen betydning?
Internasjonal PolitikkArtikkelen er en personlig vurdering av betydningen til Arktisk råd etter å ha vært såkalt SAO Chair i to år. Abstract in English Does the Arctic Council Matter?
Morten Høglund
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China, Republic of Korea and Japan in the Arctic: politics, economy, security [PDF]
Арктика и Север, 2016 China, South Korea and Japan are actively pursuing scientific, economic and political activities for the development of the Arctic, the Arctic resources, ensure security in it, seeking to increase its role in the Arctic Council, cooperating and competing-
Valeriy P. Zhuravel
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Molecular Oncology, EarlyView.Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla +9 more
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Internationalization of Vocational Education in the Arctic Council Member-States’ Universities
Арктика и Север, 2020 Nowadays, the potential for international cooperation in the Arctic is concentrated within the framework of such an influential international structure as the Arctic Council, where Russia is presiding over soon in 2021–2023.
Maria A. PITUKHINA
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KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer
Molecular Oncology, EarlyView.Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan +16 more
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Russia’s Security Perceptions and Arctic Governance
Politics and GovernanceRussia’s war in Ukraine further strained Russia’s relations with the West and negatively influenced Arctic regional governance, especially after seven members of the Arctic Council paused cooperation with Russia.
Angela Borozna
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