Results 221 to 230 of about 57,296 (333)

Gut Microbiota‐Butyrate‐PPARγ Axis Modulates Adipose Regulatory T Cell Population

Advanced Science, EarlyView.
This study identifies the indispensable role of gut microbiota in the maintenance of ST2+ adipose Treg cell population, and defines gut microbiota‐derived butyrate as an endogenous PPARγ agonist, modulating adipose Treg cell populations via promoting PPARγ activation. Butyrate or fiber supplementation restores the VAT ST2+ Treg population in obese mice
Banru Chen, Lizhi Guan, Chao Wu, Yiwen Gong, Lei Wu, Minchun Zhang, Zhiwen Cao, Yufei Chen, Chengcan Yang, Bing Wang, Yunqi Li, Bin Li, Yufang Bi, Guang Ning, Jiqiu Wang, Weiqing Wang, Ruixin Liu   +16 more
wiley   +1 more source

Performance Evaluation of Deep Learning Image Classification Modules in the MUN-ABSAI Ice Risk Management Architecture. [PDF]

Sensors (Basel)
Thalagala RG, De Silva O, Oldford D, Molyneux D.   +3 more
europepmc   +1 more source

Impact of Holocene environmental change on the evolutionary ecology of an Arctic top predator. [PDF]

Sci Adv, 2023
Westbury MV, Brown SC, Lorenzen J, O'Neill S, Scott MB, McCuaig J, Cheung C, Armstrong E, Valdes PJ, Samaniego Castruita JA, Cabrera AA, Blom SK, Dietz R, Sonne C, Louis M, Galatius A, Fordham DA, Ribeiro S, Szpak P, Lorenzen ED.   +19 more
europepmc   +1 more source

Copy Number Gains of VPS72 Drive De Novo Lipogenesis and Hepatocarcinogenesis via ATF3/mTORC1/SREBP1 Axis

Advanced Science, EarlyView.
VPS72 overexpression activates mTORC1 signaling, subsequently promoting lipid synthesis and driving HCC progression. VPS72 modulates the epigenetic landscape of ATF3 promoter, such as H2A.Z acetylation reduction and DNA methylation increase, which results in ATF3 repression and subsequent activation of mTORC1.
Qinglin Zhang, Yunxing Huang, Yin Tong, Kenneth Tsz Chun Ng, Jiangwen Zhang   +4 more
wiley   +1 more source

Drivers of summer Arctic sea-ice extent at interannual time scale in CMIP6 large ensembles revealed by information flow. [PDF]

Sci Rep
Docquier D, Massonnet F, Ragone F, Sticker A, Fichefet T, Vannitsem S.   +5 more
europepmc   +1 more source

Supplementary material to "Microphysical sensitivity of coupled springtime Arctic stratocumulus to modelled primary ice over the ice pack, marginal ice, and ocean"

, 2016
Gillian Young, Paul Connolly, Hazel M. Jones, T. W. Choularton   +3 more
openalex   +1 more source

PRMT1 Ablation in Endothelial Cells Causes Endothelial Dysfunction and Aggravates COPD Attributable to Dysregulated NF‐κB Signaling

Advanced Science, EarlyView.
This study investigates the role of protein arginine methyltransferase 1 (PRMT1) in endothelial cells (ECs) in chronic obstructive pulmonary disease (COPD). Mice with endothelial‐specific PRMT1 deletion develop pulmonary hemorrhage, inflammation, and apoptosis, driven by excessive nuclear factor kappa B activation.
Thi Thuy Vy Tran, Yideul Jeong, Suwoo Kim, Ji Eun Yeom, Jinwoo Lee, Wonhwa Lee, Gyu‐Un Bae, Jong‐Sun Kang   +7 more
wiley   +1 more source

Dependency of the drag coefficient on boundary layer stability beneath drifting sea ice in the central Arctic Ocean. [PDF]

Sci Rep
Kawaguchi Y, Hoppmann M, Shirasawa K, Rabe B, Kuznetsov I.   +4 more
europepmc   +1 more source

The Marginal Ice Zone as a dominant source region of atmospheric mercury during central Arctic summertime. [PDF]

Nat Commun, 2023
Yue F, Angot H, Blomquist B, Schmale J, Hoppe CJM, Lei R, Shupe MD, Zhan L, Ren J, Liu H, Beck I, Howard D, Jokinen T, Laurila T, Quéléver L, Boyer M, Petäjä T, Archer S, Bariteau L, Helmig D, Hueber J, Jacobi HW, Posman K, Xie Z.   +23 more
europepmc   +1 more source

Artificial Cornea Substitute Based on Hydrogel Skeletons with Natural Stromal Hierarchical Structure and Extracellular Matrix for Sutureless Transplantation

Advanced Science, EarlyView.
Humanized corneal stroma‐like adhesive patches (HCSPs) are developed for lamellar keratoplasty and corneal perforation repair. HCSPs exhibit histological, optical, and biomechanical characteristics similar to those of the natural cornea, with improved wet tissue adhesion, anti‐degradation, and anti‐swelling capabilities compared to conventional tissue ...
Long Zhao, Zhen Shi, Xiaoyu Zhang, Jingting Wang, Shang Yang, Fuyan Wang, Tan Li, Qingjun Zhou, Ting Wang, Weiyun Shi   +9 more
wiley   +1 more source