Results 271 to 280 of about 37,305 (333)

Advances in Solid‐Phase Processing Techniques: Innovations, Applications, and Future Perspectives

Advanced Materials Technologies, EarlyView.
Based on practical manufacturing challenges, this review examines advanced solid‐phase processing techniques that overcome the inherent limitations of conventional melting‐based and traditional solid‐phase manufacturing, enabling the production of higher‐performance components at reduced cost through process innovation and improved supply‐chain ...
Tianhao Wang
wiley   +1 more source

A Historical Review of Our Knowledge of Brown Lemming Population Cycles at Barrow, Alaska: Cycles No More or Never Before. [PDF]

Animals (Basel)
Holt DW.
europepmc   +1 more source

Photonics of Topological Magnetic Textures

Advanced Optical Materials, EarlyView.
Localized noncollinear magetic textures imprint their geometry and topology onto traversing photonic fields endowing them with orbital angular‐momentum, chirality, and magnetoelectric densities. Abstract Topological textures in magnetically ordered materials are an important case studies for fundamental research with promising applications in data ...
Vakhtang Jandieri, Ramaz Khomeriki, Daniel Erni, Nicolas Tsagareli, Qian Li, Douglas H. Werner, Jamal Berakdar   +6 more
wiley   +1 more source

Physical Drivers of a Massive Harmful Algal Bloom in the Northern Bering and Chukchi Seas in Summer 2022. [PDF]

J Geophys Res Oceans
Lago LS, Pickart RS, Lin P, Bahr F, Fachon E, Brosnahan ML, Pathare M, Muhlbach E, Horn K, Rajagopalan A, Anderson DM.   +10 more
europepmc   +1 more source

Phase‐Separation of YAP Mediates AJUBA Super Enhancer Activation to Promote Aberrant Mitosis in Breast Cancer

Advanced Science, EarlyView.
YAP undergoes phase separation to activate the AJUBA super‐enhancer, driving aberrant mitosis through spindle checkpoint dysregulation in breast cancer. This study uncovers a mechanistic link between YAP condensates, super‐enhancer activation, and aneuploidy formation.
Rui Zhang, Qingwen Huang, Zhuo Chen, Weijian Meng, Hongliang Dong, Zhihong Qi, Liang Liu, Jie Shen, Daxing Xie   +8 more
wiley   +1 more source

Impacts of Antarctic summer sea-ice extremes. [PDF]

PNAS Nexus
Doddridge EW, Hobbs WR, Auger M, Boyd PW, Chua SMT, Cook S, Corney S, Emmerson L, Fraser AD, Heil P, Kelly N, Lannuzel D, Li X, Liniger G, Massom RA, Meyer A, Reid P, Southwell C, Spence P, Steketee A, Swadling KM, Teder N, Wienecke B, Wongpan P, Yamazaki K.   +24 more
europepmc   +1 more source

Multiomics Analyses Reveal an Essential Role of Tryptophan in Treatment of csDMARDs in Rheumatoid Arthritis

Advanced Science, EarlyView.
Rheumatoid arthritis is a disease characterized by joint inflammation. Approximately 50% of patients show insufficient response to traditional synthetic disease‐modifying antirheumatic drugs. This study aims to elucidate differential molecular profiles of the mechanisms underlying drug responses through multi‐omics strategy.
Congcong Jian, Jing Zhu, Jianhong Wu, Yan Zhang, Jianghua Chen, Huan Wang, Hengyan Liu, Ke Xu, Jiaxin Huang, Xiaoting Zhu, Yuanli Wei, Shilin Li, Tingting Wang, Xuan Huang, Qinghua Zou, Jie Zhang, Jiang Su, Xinming Du, Yaping Lu, Tianci Zhou, Yingtong Zhou, Minglong Tang, Bin Li, Xue Zhou, Qihao Wei, Qiulong Yan, Fanxin Zeng   +26 more
wiley   +1 more source

Evolving Arctic maritime hazards: Declining sea ice and rising waves in the Northwest Passage. [PDF]

Proc Natl Acad Sci U S A
Henke MT, Miesse T, de Souza de Lima A, Ferreira C, Ravens T, Pundt R.   +5 more
europepmc   +1 more source

RIG‐I Mediated Neuron‐Specific IFN Type 1 Signaling in FUS‐ALS Induces Neurodegeneration and Offers New Biomarker‐Driven Individualized Treatment Options for (FUS‐)ALS

Advanced Science, EarlyView.
Using iPSC‐derived motoneurons and postmortem tissue from FUS‐ALS patients, it is demonstrated that increased mitochondrial transcription leads to elevated cytosolic double‐stranded RNA (dsRNA) levels. This aberrant accumulation activates a RIG‐I–dependent innate immune response leading to neurodegeneration, which is amenable for FDA‐ and EMA‐approved ...
Marcel Naumann, Theresa M. Wierschin, Stefanie Kretschmer, Banaja P. Dash, Aaron Held, Andrea Salzinger, Kevin Peikert, Anže Karlek, Hannes Glaß, Dajana Großmann, René Günther, Susanne Petri, Annekathrin Rödiger, David Brenner, Francisco Pan‐Montojo, Eleonora Aronica, Markus Kipp, Vitaly Zimyanin, Jared Sterneckert, Torsten Grehl, Noah D. Seebacher, Tobias M. Böckers, Alberto Catanese, Brian J. Wainger, Patrick Oeckl, Min Ae Lee‐Kirsch, Andreas Hermann   +26 more
wiley   +1 more source