Results 51 to 60 of about 1,255 (262)

Automatic detection of Arctic polynyas using hybrid supervised-unsupervised deep learning [PDF]

The Cryosphere
Polynyas are open water or thin-ice areas within the ice pack. They play a crucial role for the Earth system, from deep water to cloud formation, causing large gas exchanges, and acting as hotspots for marine life.
C. Heuzé, C. H. M. Wong
doaj   +1 more source

Monitoring of circulating tumor DNA allows early detection of disease relapse in patients with operable breast cancer

Molecular Oncology, EarlyView.
Monitoring circulating tumor DNA (ctDNA) in patients with operable breast cancer can reveal disease relapse earlier than radiology in a subset of patients. The failure to detect ctDNA in some patients with recurrent disease suggests that ctDNA could serve as a supplement to other monitoring approaches.
Kristin Løge Aanestad, Marie Austdal, Oddmund Nordgård, Gunnar Mellgren, Satu Oltedal, Marie L. Austbø, Ylva H. Vignes, Thomas Helland, Kristin Jonsdottir, Tone H. Lende, Emilius A. M. Janssen, Bjørnar Gilje, Kjersti Tjensvoll, PBCB study group, Gunnar Mellgren, Tone Hoel Lende, Anette Heie, Kristin Viste, Anita Røyneberg Alvheim, Emiel AM Janssen, Kristin Jonsdottir, Ann Cathrine Kroksveen, Thomas Helland, Einar Gudlaugsson, Oddmund Nordgård, Satu Oltedal, Kristin Løge Aanestad, Jan Terje Kvaløy, Kirsten Lode, Kari Britt Hagen, Marie Austdal, Ylva H. Vignes, Siri Tungland Sola, Nina Egeland Amundsen, Finn Magnus Eliassen, Emeritus Ernst A Lien   +35 more
wiley   +1 more source

The seeding of ice algal blooms in Arctic pack ice: The multiyear ice seed repository hypothesis

Journal of Geophysical Research: Biogeosciences, 2017
Source at http://dx.doi.org/10.1002/2016JG003668
Olsen, Lasse Mork, Laney, Samuel R., Duarte, Pedro, Kauko, Hanna M., Fernández-Méndez, Mar, Mundy, Christopher John, Rösel, Anja, Meyer, Amelie, Itkin, Polona, Cohen, Lana, Peeken, Ilka, Tatarek, Agnieszka, Róźańska-Pluta, Magdalena, Wiktor, Josef, Taskjelle, Torbjørn, Pavlov, Alexey, Hudson, Stephen R., Granskog, Mats A., Hop, Haakon, Assmy, Philipp   +19 more
openaire   +6 more sources

CLIMATE CHANGE AT HIGH LATITUDES: AN ILLUMINATING EXAMPLE

Zygon, 2018
A striking example is presented of a newly observed phenomenon in the ice‐covered Arctic Ocean that appears to be a consequence of changes in the physical forcing.
doaj   +2 more sources

Environmental drivers of under-ice phytoplankton bloom dynamics in the Arctic Ocean

Elementa: Science of the Anthropocene, 2020
The decline of sea-ice thickness, area, and volume due to the transition from multi-year to first-year sea ice has improved the under-ice light environment for pelagic Arctic ecosystems.
Mathieu Ardyna, C. J. Mundy, Matthew M. Mills, Laurent Oziel, Pierre-Luc Grondin, Léo Lacour, Gauthier Verin, Gert Van Dijken, Joséphine Ras, Eva Alou-Font, Marcel Babin, Michel Gosselin, Jean-Éric Tremblay, Patrick Raimbault, Philipp Assmy, Marcel Nicolaus, Hervé Claustre, Kevin R. Arrigo   +17 more
doaj   +1 more source

Can marine micro‐organisms influence melting of the Arctic pack ice? [PDF]

Eos, Transactions American Geophysical Union, 2004
The Arctic Ocean Expedition of 2001 (AOE‐2001) to the central Arctic, mostly north of latitude 85°N, was conducted to study marine life forms and their products in water and ice, how their products may get into the air, the evolution of the particles produced, and their growth up to sizes large enough for activation into clouds.
Caroline Leck, Michael Tjernström, Patrica Matrai, Erik Swietlicki, Keith Bigg   +4 more
openaire   +1 more source

ATF4‐mediated stress response as a therapeutic vulnerability in chordoma

Molecular Oncology, EarlyView.
We screened 5 chordoma cell lines against 100+ inhibitors of epigenetic and metabolic pathways and kinases and identified halofuginone, a tRNA synthetase inhibitor. Mechanistically halofuginone induces an integrated stress response, with eIF2alpha phosphorylation, activation of ATF4 and its target genes CHOP, ASNS, INHBE leading to cell death ...
Lucia Cottone, James Dunford, Eleanor Calcutt, Vicki Gamble, Filiz Senbabaoglu Aksu, Lorena Ligammari, Georgina Wherry, Giorgia Gaeta, John C. Christianson, Adrienne M. Flanagan, Udo Oppermann, Adam P. Cribbs   +11 more
wiley   +1 more source

Floating ice-algal aggregates below melting arctic sea ice. [PDF]

PLoS ONE, 2013
During two consecutive cruises to the Eastern Central Arctic in late summer 2012, we observed floating algal aggregates in the melt-water layer below and between melting ice floes of first-year pack ice.
Philipp Assmy, Jens K Ehn, Mar Fernández-Méndez, Haakon Hop, Christian Katlein, Arild Sundfjord, Katrin Bluhm, Malin Daase, Anja Engel, Agneta Fransson, Mats A Granskog, Stephen R Hudson, Svein Kristiansen, Marcel Nicolaus, Ilka Peeken, Angelika H H Renner, Gunnar Spreen, Agnieszka Tatarek, Jozef Wiktor   +18 more
doaj   +1 more source

Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin

Molecular Oncology, EarlyView.
The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla, Jan Kosla, Magdalena Prechova, Lukas Frick, Patricia Bortel, Yasmin Borutzki, Andrea Bileck, Christopher Gerner, Samuel M. Meier‐Menches, Selma Osmanagic‐Myers, Martin Gregor   +10 more
wiley   +1 more source

Unprecedented Beaufort Sea ice loss in late summer 2021 and its relationship to an extended period of unusually stormy weather

Environmental Research Letters
Previous case studies have linked cyclone-induced atmospheric forcing and/or upper-ocean processes to notable Arctic sea ice loss events in the summers of 2012 and 2016.
Thomas J Ballinger, Peter M Finocchio, Vladimir A Alexeev, Igor V Polyakov, James D Doyle, Matthew G Fearon, Linette Boisvert, Chelsea Parker   +7 more
doaj   +1 more source