Results 41 to 50 of about 726,424 (281)
Polarimetric Scattering Model for Methane Bubbles Trapped in the Ice of Sub-Artic Lakes [PDF]
, 2012 In this work we propose a model for the polarimetric backscattering of shallow sub-arctic lakes, which are frozen usually up to two meters depth during winter.
Kostas Papathanassiou +3 more
core +1 more source
The number and distribution of polar bears in the western Barents Sea
Polar Research, 2017 Polar bears have experienced a rapid loss of sea-ice habitat in the Barents Sea. Monitoring this subpopulation focuses on the effects on polar bear demography.
Jon Aars +7 more
doaj +1 more source
Hydraulic controls of summer Arctic pack ice albedo [PDF]
Journal of Geophysical Research: Oceans, 2004 Linkages between albedo, surface morphology, melt pond distribution, and properties of first‐year and multiyear sea ice have been studied at two field sites in the North American Arctic between 1998 and 2001. It is shown that summer sea‐ice albedo depends critically on surface melt‐pond hydrology, controlled by melt rate, ice permeability, and ...
H. Eicken +4 more
openaire +1 more source
FEBS Letters, EarlyView.Encapsulins are protein nanocompartments that play an important role in iron storage. In the Myxococcus xanthus encapsulin system, two cargo proteins called EncB and EncC contribute to iron mineralization. Here, we show that EncB and EncC generate iron‐containing minerals with distinct chemical compositions, suggesting that the composition of stored ...
Harry B. McDowell +2 more
wiley +1 more source
Frontiers in Earth Science, 2018 An ice watch, encompassing visual observation of sea ice conducted from the ship's bridge, is typically performed on sea-ice oriented research cruises.
Jennifer K. Hutchings, M. Kate Faber
doaj +1 more source
Molecular Oncology, EarlyView.Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla +9 more
wiley +1 more source
Finding novel vulnerabilities of hypomorphic BRCA1 alleles
Molecular Oncology, EarlyView.Synthetic lethality screens performed to identify novel vulnerabilities often model complete gene loss, thereby overlooking patient‐derived hypomorphic mutations. In this study, we have performed genome‐wide CRISPR screens on BRCA1 hypomorphic mutations, showing BRCA1I26A behaves like wild‐type, while BRCA1R1699Q mimics deficiency. Furthermore, we have
Anne Schreuder +10 more
wiley +1 more source
Winter sea ice export from the Laptev Sea preconditions the local summer sea ice cover and fast ice decay [PDF]
The Cryosphere, 2017 Ice retreat in the eastern Eurasian Arctic is a consequence of atmospheric and oceanic processes and regional feedback mechanisms acting on the ice cover, both in winter and summer.
P. Itkin, P. Itkin, T. Krumpen
doaj +1 more source
MITF maintains genome stability in nonmelanocyte lineages
Molecular Oncology, EarlyView.MITF is essential for melanocyte survival and acts as an oncogene in 10%–20% of melanomas. We show that MITF depletion causes genome instability in nonmelanocytic cells, leading to LATS2‐mediated P53 activation, cell cycle arrest, and apoptosis. This study highlights the role of MITF as a genome maintenance factor beyond the melanocyte lineage. Created
Drifa H. Gudmundsdottir +13 more
wiley +1 more source
Transition in the fractal geometry of Arctic melt ponds [PDF]
The Cryosphere, 2012 During the Arctic melt season, the sea ice surface undergoes a remarkable transformation from vast expanses of snow covered ice to complex mosaics of ice and melt ponds.
C. Hohenegger +4 more
doaj +1 more source