Results 51 to 60 of about 2,485 (283)

The effect of sea-ice loss on beluga whales (Delphinapterus leucas) in West Greenland

, 2010
An aerial survey was conducted to estimate the abundance of belugas (Delphinapterus leucas) on their wintering ground in West Greenland in March–April 2006 and 2008.
Marques, Tiago A., Stern, H., Simon, M., Heide-Jørgensen, M.P., Heide-Jørgensen, M. P., Borchers, D., Laidre, K.L., Borchers, David Louis, Laidre, K. L., Marques, T.A.   +9 more
core   +1 more source

Regime-dependence when constraining a sea ice model with observations: lessons from a single-column perspective [PDF]

The Cryosphere
A substantial body of work has explored the use of sea ice concentration (SIC) and sea ice thickness (SIT) observations to initialize modeled estimates of the unobserved Arctic sea ice state via data assimilation (DA).
M. M. Wieringa, M. M. Wieringa, C. M. Bitz   +2 more
doaj   +1 more source

CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3

Molecular Oncology, EarlyView.
PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh, Nitzan Medina‐Itzhaki, Milena Chekov, Eden Gal‐Swisa, Roba Gabesh‐Wahabi, Inbar Savyon, Inna Naroditsky, Hilary A. Kenny, Basem Fares, Lina Korsensky, Einav Girsh, Liron Berger, Ruth Perets   +12 more
wiley   +1 more source

Finding novel vulnerabilities of hypomorphic BRCA1 alleles

Molecular Oncology, EarlyView.
Synthetic lethality screens performed to identify novel vulnerabilities often model complete gene loss, thereby overlooking patient‐derived hypomorphic mutations. In this study, we have performed genome‐wide CRISPR screens on BRCA1 hypomorphic mutations, showing BRCA1I26A behaves like wild‐type, while BRCA1R1699Q mimics deficiency. Furthermore, we have
Anne Schreuder, Klaas de Lint, Hồ Mỹ Phúc Võ, Mariana M. Góis, Rosalie A. Kampen, Marta San Martin Alonso, Ilse Nootenboom, Veronica Garzero, Tiemen J. Wendel, Rob M. F. Wolthuis, Sylvie M. Noordermeer   +10 more
wiley   +1 more source

Spatial Distribution of Methanesulphonic Acid in the Arctic Aerosol Collected during the Chinese Arctic Research Expedition

Atmosphere, 2015
Methanesulphonic acid (MSA, mainly derived from marine biogenic emissions) has been frequently used to estimate the marine biogenic contribution. However, there are few reports on MSA over the Arctic Ocean, especially the central Arctic Ocean.
Peipei Ye, Zhouqing Xie, Juan Yu, Hui Kang   +3 more
doaj   +1 more source

Improvement of Ice Surface Temperature Retrieval by Integrating Landsat 8/TIRS and Operation IceBridge Observations

Remote Sensing, 2023
Accurate retrieval of ice surface temperature (IST) over the Arctic ice-water mixture zone (IWMZ) is significantly essential for monitoring the change of the polar sea ice environment.
Lijuan Song, Yifan Wu, Jiaxing Gong, Pei Fan, Xiaopo Zheng, Xi Zhao   +5 more
doaj   +1 more source

MITF maintains genome stability in nonmelanocyte lineages

Molecular Oncology, EarlyView.
MITF is essential for melanocyte survival and acts as an oncogene in 10%–20% of melanomas. We show that MITF depletion causes genome instability in nonmelanocytic cells, leading to LATS2‐mediated P53 activation, cell cycle arrest, and apoptosis. This study highlights the role of MITF as a genome maintenance factor beyond the melanocyte lineage. Created
Drifa H. Gudmundsdottir, Adrián López García de Lomana, Thejus B. Venkatesh, Kritika Kirty, Snaevar Sigurdsson, Linda Vidarsdottir, Ramile Dilshat, Erla Sveinbjornsdottir, Snaedis Ragnarsdottir, Daniel H Magnusson, Maria R. Bustos, Eirikur Steingrimsson, Thorkell Gudjonsson, Stefan Sigurdsson   +13 more
wiley   +1 more source

Meltwater as a Local Source of Ice Nucleating Particles in the Central Arctic Summer

Geophysical Research Letters
Identifying sources of ice nucleating particles (INPs) in the central Arctic is important for understanding controls on the phase of Arctic mixed‐phase clouds (AMPCs).
C. E. Mavis, M. Vazquez, C. A. Bekemeier, K. R. Barry, E. J. Chamberlain, J. Schmale, T. Jokinen, T. Laurila, M. D. Shupe, C. J. M. Hoppe, A. A. Fong, M. Oggier, A. Ulfsbo, J. P. Balmonte, J. S. Bowman, T. C. J. Hill, P. J. DeMott, S. M. Kreidenweis, J. M. Creamean   +18 more
doaj   +1 more source

Sea ice meiofauna distribution on local to pan‐Arctic scales

Ecology and Evolution, 2018
Arctic sea ice provides microhabitats for biota that inhabit the liquid‐filled network of brine channels and the ice–water interface. We used meta‐analysis of 23 published and unpublished datasets comprising 721 ice cores to synthesize the variability in
Bodil A. Bluhm, Haakon Hop, Mikko Vihtakari, Rolf Gradinger, Katrin Iken, Igor A. Melnikov, Janne E. Søreide   +6 more
doaj   +1 more source

Oil tanker under ice loadings

Scientific Reports, 2023
As a result of global warming, the area of the polar pack ice is diminishing, making merchant travel more practical. Even if Arctic ice thickness reduced in the summer, fractured ice is still presenting operational risks to the future navigation.
Oleg Gaidai, Ping Yan, Yihan Xing, Jingxiang Xu, Fuxi Zhang, Yu Wu   +5 more
doaj   +1 more source