Results 71 to 80 of about 2,485 (283)

Seasonal and spatial variations in sea ice kinematics and their response to storms in the Arctic Transpolar Drift region in 2021–2022

Journal of Glaciology
Sea ice outflow through the Transpolar Drift (TPD) is essential in Arctic sea ice loss. Twenty-four buoys deployed in the Arctic Ocean during the summer of 2021 were used to analyse sea ice kinematics and deformation across the pack ice zone (PIZ) and ...
Minghao Liu, Ruibo Lei, Long Lin, Jennifer K. Hutchings, Ying Chen, Meng Qu, Xuhua Cheng   +6 more
doaj   +1 more source

Floating ice-algal aggregates below melting arctic sea ice. [PDF]

PLoS ONE, 2013
During two consecutive cruises to the Eastern Central Arctic in late summer 2012, we observed floating algal aggregates in the melt-water layer below and between melting ice floes of first-year pack ice.
Philipp Assmy, Jens K Ehn, Mar Fernández-Méndez, Haakon Hop, Christian Katlein, Arild Sundfjord, Katrin Bluhm, Malin Daase, Anja Engel, Agneta Fransson, Mats A Granskog, Stephen R Hudson, Svein Kristiansen, Marcel Nicolaus, Ilka Peeken, Angelika H H Renner, Gunnar Spreen, Agnieszka Tatarek, Jozef Wiktor   +18 more
doaj   +1 more source

Evolutionarily divergent DUF4465 domains have a common vitamin B12‐binding function

FEBS Open Bio, EarlyView.
We show that DUF4465 family proteins, widespread across bacteria from gut microbiomes, hydrothermal vents, and soil, share a common vitamin B12‐binding function. These augmented β‐jellyroll proteins bind vitamin B12 via extended loops. Our findings establish sequence‐diverse DUF4465 proteins as a widespread class of B12‐binding proteins, highlighting ...
Charlea Clarke, Michal Banasik, Rokas Juodeikis, Martin J. Warren, Richard W. Pickersgill   +4 more
wiley   +1 more source

Drivers of Changing Interannual Variability in Autumn‐Early Winter Arctic Sea Ice (1950–2024)

Geophysical Research Letters
Arctic sea ice has undergone a pronounced decline over recent decades, yet the drivers of its interannual variability remains unclear. Here we utilize standard deviation to assess long‐term changes in autumn‐early winter (October–December) Arctic sea ice
Lejiang Yu, Shiyuan Zhong, Timo Vihma
doaj   +1 more source

Hypotheses and tracking results about the longest migration: The case of the arctic tern

Ecology and Evolution, 2019
The arctic tern Sterna paradisaea completes the longest known annual return migration on Earth, traveling between breeding sites in the northern arctic and temperate regions and survival/molt areas in the Antarctic pack‐ice zone.
Thomas Alerstam, Johan Bäckman, Johanna Grönroos, Patrik Olofsson, Roine Strandberg   +4 more
doaj   +1 more source

Large‐scale bidirectional arrayed genetic screens identify OXR1 and EMC4 as modifiers of αSynuclein aggregation

FEBS Open Bio, EarlyView.
Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane, Lea Nikolić, Lorenzo Maraio, Thomas Goiran, Nathan Karpilovsky, Stefano Sellitto, Vangelis Bouris, Jiang‐An Yin, Ronald Melki, Edward A Fon, Adriano Aguzzi, Elena De Cecco   +11 more
wiley   +1 more source

Long‐term hippocampal alterations and cognitive impairment in a murine model of surgical sepsis

FEBS Open Bio, EarlyView.
Using a mouse model of surgical sepsis, we tested long‐term memory and analyzed the transcriptome of single cells isolated from the hippocampus. Survivor mice showed worse memory, loss of certain brain cell subpopulations, and abnormal immune cell activity—suggesting that post‐sepsis brain alterations may be linked to cognitive deficits.
Dong Seong Cho, Rebecca Schmitt, Aneesha Dasgupta, Alexandra Ducharme, Jason Doles   +4 more
wiley   +1 more source

The Best Laid Schemes: A Nares Strait Adventure [PDF]

Oceanography, 2011
In 2002, oceanographers began a study of Arctic freshwater export via Nares Strait (Münchow et al., 2006). This 550 km channel separating Greenland from Canada is possibly the longest narrow waterway on Earth.
Humfrey Melling
doaj  

Identifying transcription factors controlling the basal expression of human MRP4 highlights a substantial role for Sp1

FEBS Open Bio, EarlyView.
The MRP4 transporter exports several drugs and signaling molecules. Here, we identified key promoter elements regulating basal MRP4 expression. Using reporter assays, we defined a conserved region with essential Sp1 and contributory Ets sites, which controlled basal MRP4 expression.
Debora Singer, Angelique Kragl, Katrin Ziems, Juliane Glaubitz, Sophie Grammbauer, Susanne Hildebrandt, Mladen V. Tzvetkov, Gabriele Jedlitschky   +7 more
wiley   +1 more source

Derivation and characterization of retinal pigment epithelium from urine‐derived iPSCs

FEBS Open Bio, EarlyView.
Age‐related macular degeneration causes vision loss via RPE dysfunction and loss. Traditional iPSC therapies rely on invasive biopsies, limiting scalability. Here, we utilize urine‐derived stem cells as an accessible source to generate u‐iPSCs, successfully differentiated into pigmented RPE. This “Urine‐to‐Retina” platform provides a promising path for
Daniella Beiner, Hainan Zhu, Carol Christine Bosholm, Heuy‐Ching Wang, Tracy Criswell, Anthony Atala, Jian‐Xing Ma, Yuanyuan Zhang   +7 more
wiley   +1 more source