Results 81 to 90 of about 726,424 (281)

Report of Senior Arctic Officials to Ministers at the 5th Arctic Council Ministerial Meeting October 2006 [PDF]

, 2006
Report of Senior Arctic Official to Arctic Council Ministers, Salekhard, Russian Federation, October 2006. Reviews the progress reports of the Working Groups and priorities of the Arctic Council moving forward into the next interministerial ...
Arctic Council, -
core   +1 more source

Dose‐dependent hepatotoxicity of hydrogen peroxide in HepG2 cells and its modulation by CYP450 induction

FEBS Open Bio, EarlyView.
NMR metabolomics revealed concentration‐dependent metabolic perturbations in HepG2 cells exposed to H2O2. Rifampicin pretreatment enhanced metabolic competence, attenuated toxin‐induced alterations and produced metabolite profiles more consistent with human liver physiology, supporting the use of CYP450‐induced HepG2 models for improved in vitro ...
Maren Jinks, Garth L. Maker, Emily C. Davies, Berin A. Boughton, Samantha Lodge   +4 more
wiley   +1 more source

Arctic Environmental Protection Strategy [PDF]

, 1991
In September 1989, on the initiative of the government of Finland, officials from the eight Arctic countries met in Rovaniemi, Finland to discuss cooperative measures to protect the Arctic environment. They agreed to work towards a meeting of circumpolar
Arctic Council, -
core   +1 more source

The Best Laid Schemes: A Nares Strait Adventure [PDF]

Oceanography, 2011
In 2002, oceanographers began a study of Arctic freshwater export via Nares Strait (Münchow et al., 2006). This 550 km channel separating Greenland from Canada is possibly the longest narrow waterway on Earth.
Humfrey Melling
doaj  

ATZ‐1 promotes DNA replication efficiency to maintain normal meiotic function

FEBS Open Bio, EarlyView.
Absence of ATZ‐1 interferes with meiotic DNA replication and cell cycle function via CHK‐1. This causes downstream defects associated with DNA damage and genomic integrity. Taken together, this study suggests that ATZ‐1 influences DNA replication efficiency and cell cycle function to maintain normal meiotic function.
Taylin E. Gourley, Luke W. Molesworth, Nethma H. Waduge, Fahimeh Eskandari, Peter R. Boag, Gregory M. Davis   +5 more
wiley   +1 more source

Summertime ice-nucleating particle concentrations over the Eurasian-Arctic Seas [PDF]

Atmospheric Chemistry and Physics
Ice nucleating particles (INPs) catalyze primary ice formation in Arctic low-level mixed-phase clouds, influencing their persistence and radiative properties. Knowledge of the abundance, sources, and nature of INPs over the remote Arctic Ocean is scarce,
G. Li, G. Li, A. Welti, I. Thurnherr, U. Lohmann, Z. A. Kanji   +5 more
doaj   +1 more source

Structural studies and functional engineering of NanX: an anhydro‐sialic acid transporter from Escherichia coli

FEBS Open Bio, EarlyView.
Biophysical characterisation shows that NanX, a membrane transport protein from the major facilitator superfamily (MFS), forms both monomers and dimers after purification. AlphaFold modelling and substrate docking provide information on residues likely involved in substrate recognition for NanX and another MFS member, NanT.
Michael C. Newton‐Vesty, Kelsi R. Hall, Zachary D. Tillett, Liam S. Turk, James S. Davies, Michael J. Currie, Hamish G. Brown, Sepideh Valimehr, Peter D. Mace, Andrew E. Whitten, Santosh Panjikar, Eric Hanssen, Rachel A. North, Renwick C.J. Dobson   +13 more
wiley   +1 more source

Purification and preparation of Marchantia polymorpha Auxin Response Factor 2 for phase separation studies

FEBS Open Bio, EarlyView.
We describe detailed protocols for the purification and preparation of Marchantia polymorpha Auxin Response Factor 2 (MpARF2). This protein is fused to an MBP solubility tag and an mNG fluorescent tag and is purified from Escherichia coli. The presented procedures make it possible to study MpARF2 assemblies, which could arise from phase separation ...
Bas Janssen, Robin Romein, Willy A. M. van den Berg, Simon Lindhoud, Jan Willem Borst, Carlo P. M. van Mierlo   +5 more
wiley   +1 more source

Protocol for quantifying miRNA trafficking across the endosomal membrane

FEBS Open Bio, EarlyView.
An in vitro protocol measures miRNA uptake into endosomes isolated from mammalian cell extracts, which are free of subcellular contaminants. Performed at 37 °C in the presence of ATP, it ensures the import of single‐stranded miRNA into the endosomal lumen.
Syamantak Ghosh, Kamalika Mukherjee, Suvendra N. Bhattacharyya   +2 more
wiley   +1 more source

Arctic Climate Impact Assessment - Policy Document [PDF]

, 2004
Arctic Climate Impact Assessment - Policy Document.
Arctic Council, -
core   +1 more source