Results 81 to 90 of about 37,429 (292)

The seasonal cycle of ocean-atmosphere CO2 Flux in Ryder Bay, West Antarctic Peninsula [PDF]

, 2015
Approximately 15 million km2 of the Southern Ocean is seasonally ice covered, yet the processes affecting carbon cycling and gas exchange in this climatically important region remain inadequately understood.
Arrigo, Bakker, Bakker, Bates, Delille, Delille, Dickson, Dieckmann, Dorothee C. E. Bakker, Fairall, Fletcher, Gareth A. Lee, Geilfus, Gibson, Gosink, Goyet, Gruber, Hugh J. Venables, Johnson, Lavergne, Le Quéré, Lenton, Lenton, Li, Loose, Loose, Lovenduski, Martin T. Johnson, Meredith, Meredith, Meredith, Michael P. Meredith, Miller, Millero, Mintrop, Mucci, Nomura, Oliver J. Legge, Papadimitriou, Peter J. Brown, Purkey, Roden, Rysgaard, Rysgaard, Semiletov, Stammerjohn, Stephens, Sweeney, Takahashi, Thompson, Vaughan, Venables, Venables, Wanninkhof, Wanninkhof, Wanninkhof, Weiss, Weiss, Zemmelink   +58 more
core   +1 more source

Large‐scale bidirectional arrayed genetic screens identify OXR1 and EMC4 as modifiers of αSynuclein aggregation

FEBS Open Bio, EarlyView.
Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane, Lea Nikolić, Lorenzo Maraio, Thomas Goiran, Nathan Karpilovsky, Stefano Sellitto, Vangelis Bouris, Jiang‐An Yin, Ronald Melki, Edward A Fon, Adriano Aguzzi, Elena De Cecco   +11 more
wiley   +1 more source

Concentrations and snow-atmosphere fluxes of reactive nitrogen at Summit, Greenland [PDF]

, 1999
Concentrations and fluxes of NOy (total reactive nitrogen), ozone concentrations and fluxes of sensible heat, water vapor, and momentum were measured from May 1 to July 20, 1995 at Summit, Greenland. Median NOy concentrations declined from 947 ppt in May
Colman, A S, Dibb, Jack E., Fan, S M, Jacob, D J, Munger, J W   +4 more
core   +2 more sources

Long‐term hippocampal alterations and cognitive impairment in a murine model of surgical sepsis

FEBS Open Bio, EarlyView.
Using a mouse model of surgical sepsis, we tested long‐term memory and analyzed the transcriptome of single cells isolated from the hippocampus. Survivor mice showed worse memory, loss of certain brain cell subpopulations, and abnormal immune cell activity—suggesting that post‐sepsis brain alterations may be linked to cognitive deficits.
Dong Seong Cho, Rebecca Schmitt, Aneesha Dasgupta, Alexandra Ducharme, Jason Doles   +4 more
wiley   +1 more source

The Best Laid Schemes: A Nares Strait Adventure [PDF]

Oceanography, 2011
In 2002, oceanographers began a study of Arctic freshwater export via Nares Strait (Münchow et al., 2006). This 550 km channel separating Greenland from Canada is possibly the longest narrow waterway on Earth.
Humfrey Melling
doaj  

An Assessment of State-of-the-Art Mean Sea Surface and Geoid Models of the Arctic Ocean: Implications for Sea Ice Freeboard Retrieval [PDF]

, 2017
State-of-the-art Arctic Ocean mean sea surface (MSS) models and global geoid models (GGMs) are used to support sea ice freeboard estimation from satellite altimeters, as well as in oceanographic studies such as mapping sea level anomalies and mean ...
Andersen, Ole Baltazar, Armitage, Thomas W. K., Baker, Steven, Farrell, Sinéad Louise, Haas, Christian, Hendricks, Stefan, Ricker, Robert, Ridout, Andy, Skourup, Henriette   +8 more
core   +2 more sources

Identifying transcription factors controlling the basal expression of human MRP4 highlights a substantial role for Sp1

FEBS Open Bio, EarlyView.
The MRP4 transporter exports several drugs and signaling molecules. Here, we identified key promoter elements regulating basal MRP4 expression. Using reporter assays, we defined a conserved region with essential Sp1 and contributory Ets sites, which controlled basal MRP4 expression.
Debora Singer, Angelique Kragl, Katrin Ziems, Juliane Glaubitz, Sophie Grammbauer, Susanne Hildebrandt, Mladen V. Tzvetkov, Gabriele Jedlitschky   +7 more
wiley   +1 more source

SEASAT views oceans and sea ice with synthetic aperture radar [PDF]

Fifty-one SEASAT synthetic aperture radar (SAR) images of the oceans and sea ice are presented. Surface and internal waves, the Gulf Stream system and its rings and eddies, the eastern North Pacific, coastal phenomena, bathymetric features, atmospheric ...
Fu, L. L., Holt, B.
core   +1 more source

Derivation and characterization of retinal pigment epithelium from urine‐derived iPSCs

FEBS Open Bio, EarlyView.
Age‐related macular degeneration causes vision loss via RPE dysfunction and loss. Traditional iPSC therapies rely on invasive biopsies, limiting scalability. Here, we utilize urine‐derived stem cells as an accessible source to generate u‐iPSCs, successfully differentiated into pigmented RPE. This “Urine‐to‐Retina” platform provides a promising path for
Daniella Beiner, Hainan Zhu, Carol Christine Bosholm, Heuy‐Ching Wang, Tracy Criswell, Anthony Atala, Jian‐Xing Ma, Yuanyuan Zhang   +7 more
wiley   +1 more source

A review of data on abundance, trends in abundance, habitat use and diet of ice-breeding seals in the Southern Ocean [PDF]

, 2012
The development of models of marine ecosystems in the Southern Ocean is becoming increasingly important as a means of understanding and managing impacts such as exploitation and climate change.
Bengston, J., Bester, M., Blix, A.S., Bornemann, H., Boveng, P., Cameron, M., Forcada, J., Laake, J., Nordøy, E., Plötz, J., Rogers, T., Southwell, C., Southwell, D., Steinhage, D., Stewart, B.S., Trathan, P.   +15 more
core