Results 81 to 90 of about 57,296 (333)
On the ocean wave attenuation rate in grease-pancake ice, a comparison of viscous layer propagation models with field data [PDF]
, 2018 The ability of viscous layer models to describe the attenuation of waves propagating in grease-pancake ice covered ocean is investigated. In particular, the Keller's model Keller [1998], the two-layer viscous model [De Carolis and Desiderio 2002] and the close-packing model [De Santi and Olla 2017] are extensively validated by using wave attenuation ...
arxiv +1 more source
Climate Models Underestimate the Sensitivity of Arctic Sea Ice to Carbon Emissions [PDF]
arXiv, 2023 Arctic sea ice has steadily diminished as atmospheric greenhouse gas concentrations have increased. Using observed data from 1979 to 2019, we estimate a close contemporaneous linear relationship between Arctic sea ice area and cumulative carbon dioxide emissions. For comparison, we provide analogous regression estimates using simulated data from global
arxiv
Molecular Oncology, EarlyView.This study investigates an alternative approach to reactivating the oncosuppressor p53 in cancer. A short peptide targeting the association of the two p53 inhibitors, MDM2 and MDM4, induces an otherwise therapeutically active p53 with unique features that promote cell death and potentially reduce toxicity towards proliferating nontumor cells.
Sonia Valentini +10 more
wiley +1 more source
Molecular Oncology, EarlyView.TGF‐β has a complex role in cancer, exhibiting both tumor‐suppressive and tumor‐promoting properties. Using a series of differentiated tumoroids, derived from different stages and mutational background of colorectal cancer patients, we replicate this duality of TGF‐β in vitro. Notably, the atypical but highly aggressive KRASQ22K mutation rendered early‐
Theresia Mair +17 more
wiley +1 more source
Atmospheric conditions during the Arctic Clouds in Summer Experiment (ACSE): Contrasting open-water and sea-ice surfaces during melt and freeze-up seasons [PDF]
, 2016 The Arctic Clouds in Summer Experiment (ACSE) was conducted during summer and early autumn 2014, providing a detailed view of the seasonal transition from ice melt into freeze-up.
Achtert +81 more
core +1 more source
Molecular Oncology, EarlyView.Chronic TGF‐β exposure drives epithelial HCC cells from a senescent state to a TGF‐β resistant mesenchymal phenotype. This transition is characterized by the loss of Smad3‐mediated signaling, escape from senescence, enhanced invasiveness and metastatic potential, and upregulation of key resistance modulators such as MARK1 and GRM8, ultimately promoting
Minenur Kalyoncu +11 more
wiley +1 more source
PLoS ONE, 2021 Echolocation signals of wild beluga whales (Delphinapterus leucas) were recorded in 2013 using a vertical, linear 16-hydrophone array at two locations in the pack ice of Baffin Bay, West Greenland.
Marie J Zahn +4 more
doaj +1 more source
Molecular Oncology, EarlyView.We identified adaptor protein ShcD as upregulated in triple‐negative breast cancer and found its expression to be correlated with reduced patient survival and increased invasion in cell models. Using a proteomic screen, we identified novel ShcD binding partners involved in EGFR signaling pathways.
Hayley R. Lau +11 more
wiley +1 more source
The Best Laid Schemes: A Nares Strait Adventure [PDF]
Oceanography, 2011 In 2002, oceanographers began a study of Arctic freshwater export via Nares Strait (Münchow et al., 2006). This 550 km channel separating Greenland from Canada is possibly the longest narrow waterway on Earth.
Humfrey Melling
doaj
Hypotheses and tracking results about the longest migration: The case of the arctic tern
Ecology and Evolution, 2019 The arctic tern Sterna paradisaea completes the longest known annual return migration on Earth, traveling between breeding sites in the northern arctic and temperate regions and survival/molt areas in the Antarctic pack‐ice zone.
Thomas Alerstam +4 more
doaj +1 more source