Results 71 to 80 of about 129,392 (313)

O MEDICINES IN THE ARCTIC DISTRICTS OF THE SAKHA REPUBLIC (YAKUTIA)

Север и рынок: формирование экономического порядка, 2023
Access to medicines is intrinsically linked to fundamental human rights to health and life. The need to make medicines more accessible is articulated in strategic planning documents, including the Strategy for the Development of the Arctic Zone of the Russian Federation and National Security until 2035.
Sardana M. Tarabukina, Anna N. Shishigina   +1 more
openaire   +1 more source

EGFR‐STAT3 activation provides a therapeutic rationale for targeting aggressive ETV1‐positive prostate cancer

Molecular Oncology, EarlyView.
Cotargeting EGFR and STAT3 with Erlotinib and TTI‐101 impairs both 2D and 3D growth of ETV1‐overexpressing prostate cancer cells by disrupting a self‐sustaining ETV1–EGFR positive feedback loop that promotes EGFR and STAT3 expression and phosphorylation (activation).
Elsa Gomes Paiva, Bernardo Orr, Ana Azeredo, Andreia Brandão, Manuel R. Teixeira, Paula Paulo   +5 more
wiley   +1 more source

Exploring the role of cyclin D1 in the pathogenesis of multiple myeloma beyond cell cycle regulation

Molecular Oncology, EarlyView.
Cyclin D1 overexpression altered the cell adhesion pathway, while cyclin D2 upregulation had less impact on pathway enrichment analysis. Multiple myeloma (MM) patients with cyclin D1 overexpression showed reduced CD56 expression and increased circulating tumor cells (CTC) levels, suggesting that cyclin D1 may contribute to MM cell dissemination ...
Ignacio J. Cardona‐Benavides, Sara Cristobal‐Vargas, Cristina De Ramón, Elizabeta A. Rojas, Irena Misiewicz‐Krzeminska, Isabel Isidro, José Juan Pérez, Bruno Paiva, Noemi Puig, Miguel Alcoceba, María‐Victoria Mateos, Luis A. Corchete, Myriam Cuadrado, Norma C. Gutiérrez   +13 more
wiley   +1 more source

Dataset of consumer-based activity trackers as a tool for physical activity monitoring in epidemiological studies during the COVID-19 Pandemic

Data in Brief, 2022
Physical activity (PA) data were downloaded from 113 participants who owned a Garmin or Fitbit activity tracker in 2019 and 2020. Upon participant authorization, data were automatically downloaded from the Garmin and Fitbit cloud storages.
André Henriksen, Erlend Johannessen, Gunnar Hartvigsen, Sameline Grimsgaard, Laila Arnesdatter Hopstock   +4 more
doaj   +1 more source

Olaparib synergy screen reveals Exemestane induces replication stress in triple‐negative breast cancer

Molecular Oncology, EarlyView.
Screening 166 FDA‐approved anticancer drugs identifies the aromatase inhibitor Exemestane as a synergistic partner of PARP inhibitor Olaparib in BRCA‐proficient triple‐negative breast cancer. Exemestane induces ROS‐mediated replication stress, enhancing DNA damage and apoptosis alongside Olaparib.
Nur Aininie Yusoh, Liping Su, Suet Lin Chia, Xiaohe Tian, Haslina Ahmad, Martin R. Gill   +5 more
wiley   +1 more source

Differential expression of the miR-17-92 cluster and miR-17 family in breast cancer according to tumor type; results from the Norwegian Women and Cancer (NOWAC) study

Journal of Translational Medicine, 2019
Background MicroRNAs (miRNAs) are promising biomarkers due to their structural stability and distinct expression profile in various cancers. We wanted to explore the miRNA expression in benign breast tissue and breast cancer subgroups in the Norwegian ...
Line Moi, Tonje Braaten, Khalid Al-Shibli, Eiliv Lund, Lill-Tove Rasmussen Busund   +4 more
doaj   +1 more source

Radionuclides in arctic marine macroalgae from Kongsfjorden (Svalbard) [PDF]

, 2018
Seaweeds are known to be useful environmental bioindicators since they bioaccumulate radioisotopes at very low environmental concentrations. Levels of natural radionuclides in six ecologically relevant brown and red seaweed species from Arctic coasts ...
Carmona-Fernandez, Raquel, Cañete -Hidalgo, Sergio, Dueñas-Buey, Mª Concepción, Gordo, Elisa, Liger-Pérez, Esperanza, López-Gordillo, Francisco Javier, Pastor-Vega, Jose Manuel, Perez-Martinez, Manuel, Ruiz-Cruces, Rafael   +8 more
core  

Characterizing the salivary RNA landscape to identify potential diagnostic, prognostic, and follow‐up biomarkers for breast cancer

Molecular Oncology, EarlyView.
This study explores salivary RNA for breast cancer (BC) diagnosis, prognosis, and follow‐up. High‐throughput RNA sequencing identified distinct salivary RNA signatures, including novel transcripts, that differentiate BC from healthy controls, characterize histological and molecular subtypes, and indicate lymph node involvement.
Nicholas Rajan, Irina Primac, Emre Etlioglu, Laurens Debruyne, Ann Janssen, Magy Sallam, Kevin Tabury, Roel Quintens, Wiebren Tjalma, Mohammed Abderrafi Benotmane   +9 more
wiley   +1 more source

Associations between body height and cardiovascular risk factors in women and men: a population-based longitudinal study based on The Tromsø Study 1979–2016

BMJ Open
Objectives Investigate associations between body height and cardiovascular disease risk factors at several time points in women and men across educational levels in Norway.Design Population-based longitudinal study.Setting The Tromsø Study, a population ...
Kristin Benjaminsen Borch, Tom Wilsgaard, Inger Njølstad, Anne Helen Hansen, Sondre Haakonson Arntsen   +4 more
doaj   +1 more source

Triggers, Protectors, and Predictors in Episodic Migraine. [PDF]

, 2018
PURPOSE OF REVIEW: A wide variety of triggers prompt attacks in episodic migraine. Although experimental triggers such as glyceryl trinitrate reliably produce migraine, natural triggers are much less predictable and vary in importance between individuals.
Marmura, Michael J.
core   +1 more source