Results 41 to 50 of about 13,364 (264)

Changes in sea-surface temperature and atmospheric circulation patterns associated with reductions in Arctic sea ice cover in recent decades [PDF]

Atmospheric Chemistry and Physics, 2018
In recent decades, the Arctic sea ice has been declining at a rapid pace as the Arctic warms at a rate of twice the global average. The underlying physical mechanisms for the Arctic warming and accelerated sea ice retreat are not fully understood.
L. Yu, S. Zhong
doaj   +1 more source

The planar cell polarity protein Vangl2 interacts with the PDZ‐domains of Scribble but not with a unique PDZ‐like domain in Inturned

FEBS Letters, EarlyView.
Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes, Jan Brysch, Carmen Gelze, Lilli Meier, Daniel Kümmel   +4 more
wiley   +1 more source

Biomarker Distributions in (Sub)‐Arctic Surface Sediments and Their Potential for Sea Ice Reconstructions

Geochemistry, Geophysics, Geosystems, 2020
To evaluate the present sea ice changes in a longer‐term perspective, the knowledge of sea ice variability on preindustrial and geological time scales is essential.
Henriette M. Kolling, Ruediger Stein, Kirsten Fahl, Henrik Sadatzki, Anne deVernal, Xiaotong Xiao   +5 more
doaj   +1 more source

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

FEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa, Konstantinos Makryniotis, Theofani‐Iosifina Sousani, Evangelos Topakas, Vangelis Daskalakis, Maria Dimarogona   +5 more
wiley   +1 more source

Arctic Ice Ocean Prediction System: evaluating sea-ice forecasts during Xuelong's first trans-Arctic Passage in summer 2017

Journal of Glaciology, 2019
In an effort to improve the reliability of Arctic sea-ice predictions, an ensemble-based Arctic Ice Ocean Prediction System (ArcIOPS) has been developed to meet operational demands.
Longjiang Mu, Xi Liang, Qinghua Yang, Jiping Liu, Fei Zheng   +4 more
doaj   +1 more source

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

FEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura, Shin‐ichi Tate, Kyota Yasuda   +2 more
wiley   +1 more source

Less Surface Sea Ice Melt in the CESM2 Improves Arctic Sea Ice Simulation With Minimal Non‐Polar Climate Impacts

Journal of Advances in Modeling Earth Systems, 2022
This study isolates the influence of sea ice mean state on pre‐industrial climate and transient 1850–2100 climate change within a fully coupled global model: The Community Earth System Model version 2 (CESM2).
Jennifer E. Kay, Patricia DeRepentigny, Marika M. Holland, David A. Bailey, Alice K. DuVivier, Ed Blanchard‐Wrigglesworth, Clara Deser, Alexandra Jahn, Hansi Singh, Madison M. Smith, Melinda A. Webster, Jim Edwards, Sun‐Seon Lee, Keith B. Rodgers, Nan Rosenbloom   +14 more
doaj   +1 more source

Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation

FEBS Letters, EarlyView.
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz, Mihály Mérey, Rebeka Vásárhelyi, Ramóna Pék, Victor Imburchia, László Henn, Adrián Kószó, Nicholas D. Lakin, Ivan Ahel, Sébastien Huet, Ágnes Czibula, Gyula Timinszky   +11 more
wiley   +1 more source

Spatiotemporal Variation Characteristics and Drivers of Winter Arctic Sea Ice Thickness Under the New Arctic Regime

Journal of Marine Science and Engineering
The “New Arctic” regime represents a prominent climatic feature of the Arctic Ocean under global warming, characterized by persistently low summer sea ice extent, a marked reduction in sea ice thickness, and an expansion of open water areas at high ...
Yaowei Yin, Xiaoyu Wang
doaj   +1 more source

An isoform of 14‐3‐3 protein regulates transbilayer lipid movement at the plasma membrane

FEBS Letters, EarlyView.
Loss of 14‐3‐3ζ in CHO cells confers resistance to exogenous phosphatidylserine (PS) and impairs endocytosis‐independent inward flip‐flop of fluorescent PS at the plasma membrane. RNAi‐mediated knockdown reproduces this defect, while no additive effect is seen in ATP11C‐deficient cells.
Akiko Yamaji‐Hasegawa, Akira Hattori, Masafumi Tsujimoto, Toshihide Kobayashi   +3 more
wiley   +1 more source