Results 51 to 60 of about 32,514 (263)

Arctic Sea Ice Decline [PDF]

open access: yes, 2012
The Arctic is currently undergoing rapid environmental changes (ACIA, 2005; IPCC, 2007). One of the most striking of these changes is the decline in the floating sea ice cover. Sea ice is frozen sea water that forms in winter as temperatures drop and darkness sets over the northern high latitudes.
Julienne C., Walter Meier
openaire   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

open access: yesMolecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Sea ice transport and replenishment across and within the Canadian Arctic Archipelago, 2016–2022 [PDF]

open access: yes
<jats:p>Abstract. The Canadian Arctic Archipelago (CAA) serves as both a source and a sink for sea ice from the Arctic Ocean, while also exporting sea ice into Baffin Bay.
Montpetit, Benoit   +7 more
core   +1 more source

The impact of a seasonally ice free Arctic Ocean on the temperature, precipitation and surface mass balance of Svalbard [PDF]

open access: yes, 2012
The observed decline in summer sea ice extent since the 1970s is predicted to continue until the Arctic Ocean is seasonally ice free during the 21st Century. This will lead to a much perturbed Arctic climate with large changes in ocean surface energy flux.
Valdes, P. J.   +11 more
core   +1 more source

Dimethyl fumarate combined with cisplatin at subcytotoxic doses sensitizes cervical cancer toward ferroptosis and apoptosis through GSH restriction and p53 (re)activation

open access: yesMolecular Oncology, EarlyView.
Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano   +6 more
wiley   +1 more source

COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells

open access: yesMolecular Oncology, EarlyView.
This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos   +6 more
wiley   +1 more source

Glaciochemical evidence of spatial and temporal environmental variability across Svalbard

open access: yes, 2012
Huippuvuorten lakijäätiköiltä kairatut jäänäytteet ovat osoittautuneet hyödyllisiksi arkistoiksi, jotka kattavat useita vuosisatoja ja kertovat Barentsin alueen paleoympäristöstä sekä alueen ilmaston kytköksistä Euroopan arktisiin alueisiin.
Beaudon, Emilie
core  

Late Quaternary ice-ocean interactions in central West Greenland [PDF]

open access: yes, 2011
A greater knowledge of the interactions between the Greenland Ice Sheet and climate is critical to understanding the possible impacts of future global warming, including ice sheet contribution to global sea-level rise and perturbations to ocean ...
MCCARTHY, DAVID,JOHN   +1 more
core  

Pre‐analytical optimization of cell‐free DNA and extracellular vesicle‐derived DNA for mutation detection in liquid biopsies

open access: yesMolecular Oncology, EarlyView.
Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen   +11 more
wiley   +1 more source

Shipborne visual observations of Arctic sea ice

open access: yes, 2018
Ice Watch is coordinating the collection and archival of visual sea ice observations recorded on ships in the Northern Hemisphere. Open source software, Arctic Shipborne Sea Ice Standardization Tool (ASSIST), can be used by observers to record sea ice ...
Hutchings, Jennifer K   +1 more
core   +1 more source

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