Results 61 to 70 of about 162,083 (309)

The Effect of Changing Sea Ice on the Vulnerability of Arctic Coasts [PDF]

, 2014
Shorefast sea ice prevents the interaction of the land and the ocean in the Arctic winter and influences this interaction in the summer by governing the fetch.
Anderson, R S, Barnhart, Katy R, Overeem, I   +2 more
core   +3 more sources

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

FEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Less Surface Sea Ice Melt in the CESM2 Improves Arctic Sea Ice Simulation With Minimal Non‐Polar Climate Impacts

Journal of Advances in Modeling Earth Systems, 2022
This study isolates the influence of sea ice mean state on pre‐industrial climate and transient 1850–2100 climate change within a fully coupled global model: The Community Earth System Model version 2 (CESM2).
Jennifer E. Kay, Patricia DeRepentigny, Marika M. Holland, David A. Bailey, Alice K. DuVivier, Ed Blanchard‐Wrigglesworth, Clara Deser, Alexandra Jahn, Hansi Singh, Madison M. Smith, Melinda A. Webster, Jim Edwards, Sun‐Seon Lee, Keith B. Rodgers, Nan Rosenbloom   +14 more
doaj   +1 more source

The reversibility of sea ice loss in a state-of-the-art climate model [PDF]

, 2011
Rapid Arctic sea ice retreat has fueled speculation about the possibility of threshold (or ‘tipping point’) behavior and irreversible loss of the sea ice cover. We test sea ice reversibility within a state-of-the-art atmosphere–ocean global climate model
Armour, K. C., Bitz, C. M., Blanchard-Wrigglesworth, E., Eisenman, I., McCusker, K. E.   +4 more
core  

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

FEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai, Mizuki Seo, Gyath Karadsheh, Fachrur Rizal Mahendra, Máté Á Demény, Ferenc Győry, János András Mótyán, László Fésüs, Endre Kristóf, Rini Arianti   +9 more
wiley   +1 more source

Direct determination of the air-sea CO₂ gas transfer velocity in Arctic sea-ice regions [PDF]

, 2017
The Arctic Ocean is an important sink for atmospheric CO₂. The impact of decreasing sea-ice extent and expanding marginal ice zones on Arctic air-sea CO₂ exchange depends on the rate of gas transfer in the presence of sea ice.
Anderson, LG, Brooks, IM, Crill, PM, Geibel, MC, Humborg, C, Prytherch, J, Salisbury, DJ, Thornton, BF, Tjernström, M   +8 more
core   +1 more source

The planar cell polarity protein Vangl2 interacts with the PDZ‐domains of Scribble but not with a unique PDZ‐like domain in Inturned

FEBS Letters, EarlyView.
Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes, Jan Brysch, Carmen Gelze, Lilli Meier, Daniel Kümmel   +4 more
wiley   +1 more source

Formation and propagation of great salinity anomalies [PDF]

, 2003
North Atlantic/Arctic ocean and sea ice variability for the period 1948–2001 is studied using a global Ocean General Circulation Model coupled to a dynamic/thermodynamic sea ice model forced by daily NCEP/NCAR reanalysis data [Kalnay et al., 1996 ...
Aagaard, Belkin, Curry, Deser, Dickson, Dickson, H. Haak, Hibler, Hilmer, Houghton, Häkkinen, Häkkinen, Kalnay, Köberle, Lazier, Levitus, Marsland, Vinje, Vinje   +18 more
core   +1 more source

Influence of sea ice on Arctic precipitation [PDF]

Proceedings of the National Academy of Sciences, 2015
SignificanceThere has been a growing consensus that a decrease in sea ice would cause an increase in Arctic precipitation because of the potential for increased local evaporation. We quantify the effect of sea ice on the percentage of moisture sourced from the Arctic, using measurements of the isotopic composition of precipitation at six sites across ...
Ben G, Kopec, Xiahong, Feng, Fred A, Michel, Eric S, Posmentier   +3 more
openaire   +2 more sources

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

FEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa, Konstantinos Makryniotis, Theofani‐Iosifina Sousani, Evangelos Topakas, Vangelis Daskalakis, Maria Dimarogona   +5 more
wiley   +1 more source