Results 191 to 200 of about 24,202 (294)

Roles of histone lysine methylation in neurodevelopment and related disorders

Ibrain, EarlyView.
This graphical abstract centers on the theme of dynamic balance and systematically outlines the role of histone lysine methylation in neurodevelopment and related disorders. The figure first presents two key classes of regulators that control this balance—“writers” and “erasers”—and then indicates how interactions among different epigenetic ...
Yun Chen, Yi Zhang, Hong Zhang, Xiaoli Liang   +3 more
wiley   +1 more source

Microglia in physiological conditions and the importance of understanding their homeostatic functions in the arcuate nucleus. [PDF]

Front Immunol
Guzmán-Ruíz MA, Guerrero Vargas NN, Ramírez-Carreto RJ, González-Orozco JC, Torres-Hernández BA, Valle-Rodríguez M, Guevara-Guzmán R, Chavarría A.   +7 more
europepmc   +1 more source

Satb2 regulates the development of dopaminergic neurons in the arcuate nucleus by Dlx1. [PDF]

Cell Death Dis, 2021
Zhang Q, Zhang L, Huang Y, Ma P, Mao B, Ding YQ, Song NN.   +6 more
europepmc   +1 more source

Risk of Head and Neck Cancer in Former Smokers by Subsite: A Multicenter Analysis From the INHANCE Consortium

International Journal of Cancer, EarlyView.
Tobacco use and alcohol consumption are primary risk factors for head and neck squamous cell carcinoma, with combined use occurring in three‐quarters of cases. This large international study of former smokers shows that the risk reduction effect of smoking cessation occurs more slowly for laryngeal cancer than for other head and neck cancer subsites ...
Matheus de Abreu, Luiz Paulo Kowalski, Rossana Mendoza López, Christine Barul, Loredana Radoi, Ettore Bidoli, Jerry Polesel, Victor Wunsch‐Filho, Andrew F. Olshan, Jose Zevallos, Eva Negri, Valeria Edefonti, Beata Świątkowska, Dana Mates, Eleonora Fabianova, Jolanta Lissowska, Oxana Shangina, Paul Brennan, Tamas Pandics, Luigino Dal Maso, Hal Morgenstern, Zuo‐Feng Zhang, Karl Kelsey, Michael McClean, Carlo La Vecchia, Werner Garavello, Chu Chen, Stephen M. Schwartz, Heribert Ramroth, Volker Winkler, Gabriella Cadoni, Stefania Boccia, Hermann Brenner, Gypsyamber D'Souza, Neil Gross, Joshua Muscat, Mahsa Abedini, Michele Sassano, Paolo Boffetta, Mia Hashibe, Yuan‐Chin Amy Lee, Maria Paula Curado   +41 more
wiley   +1 more source

Estradiol elicits distinct firing patterns in arcuate nucleus kisspeptin neurons of females through altering ion channel conductances. [PDF]

Elife
Qiu J, Voliotis M, Bosch MA, Li XF, Zweifel LS, Tsaneva-Atanasova K, O'Byrne KT, Rønnekleiv OK, Kelly MJ.   +8 more
europepmc   +2 more sources

Complement 3 (C3) within the hypothalamic arcuate nucleus is a potential key mediator of the effect of enhanced nutrition on reproductive development in young bull calves. [PDF]

BMC Genomics
Keogh K, Coen S, Lonergan P, Fair S, Kenny DA.   +4 more
europepmc   +1 more source

Hypervision Proton Surgery: The Future Direction of Proton Therapy

iNew Medicine, EarlyView.
ABSTRACT Proton beams provide unique physical advantages characterized by a low entrance dose, negligible exit dose, and a sharp Bragg peak, which enable superior sparing of normal tissues and support safe dose escalation for improved tumor control. However, conventional photon‐based fractionation remains widely used in proton therapy, where prolonged ...
Li Li, Shuanghu Yuan
wiley   +1 more source

Robustness of Spontaneous Polarization Through Nonlinear Directional Antagonism Without Global Inhibition

Journal of the Chinese Chemical Society, EarlyView.
The conventional “local activation–global inhibition” (LAGI) models utilize mean‐field averaging inhibition to suppress distant activations. As the inhibition diminishes with distance, LAGI models struggle to achieve robust single‐axis polarity in large systems.
Chin‐Lin Guo, Chiao‐Yu Tseng
wiley   +1 more source

Fam163a knockdown and mitochondrial stress in the arcuate nucleus of hypothalamus reduce AgRP neuron activity and differentially regulate mitochondrial dynamics in mice. [PDF]

Acta Physiol (Oxf)
Erdogan CS, Yavuz Y, Ozgun HB, Bilgin VA, Agus S, Kalkan UF, Yilmaz B.   +6 more
europepmc   +1 more source

A brainstem to hypothalamic arcuate nucleus GABAergic circuit drives feeding

, 2023
Martinez de Morentin PB, Gonzalez JA, Dowsett GK, Dowsett GK, Martynova Y, Yeo GS, Sylantyev S, Heisler LK.   +7 more
europepmc   +1 more source