Results 211 to 220 of about 366,068 (244)

The iPP Printing Paradox: Interlayer Adhesion Through Crystallization

open access: yesPolymer Engineering &Science, EarlyView.
In fused filament fabrication of isotactic polypropylene, high molecular weight and a high print speed increase the shear during deposition. This shear promotes the formation of the ductile β‐phase at the interphase, which improves interlayer adhesion, as shown by an eightfold increase in fracture energy measured via a T‐peel test on two printed ...
Paul M. H. van Heugten   +5 more
wiley   +1 more source

The Long Trajectory of Rubber Physics: 3500+ Years and Counting

open access: yesJournal of Polymer Science, EarlyView.
Natural rubber's trajectory is traced from Mesoamerican use of Castilla elastica through vulcanization and the pneumatic tire to macromolecular physics and modern solid‐state refrigeration. Illustrations of C. elastica and an H. brasiliensis plantation frame the historical progression from indigenous material, then industrial crop and on to advanced ...
Gregory B. McKenna
wiley   +1 more source

Gentiopicroside Regulates EGFR and Induces Its Lysosomal Degradation to Attenuate Heart Failure

open access: yesPhytotherapy Research, EarlyView.
GPS attenuates pressure overload‐induced cardiac remodeling by promoting lysosomal degradation of EGFR. TAC‐induced EGFR accumulation activates AKT/ERK1/2 signaling and drives pathological cardiac hypertrophy, fibrosis, apoptosis, oxidative stress, and cardiac dysfunction. GPS promotes lysosome‐dependent EGFR degradation, thereby limiting excessive AKT/
Mingzhen Cao   +6 more
wiley   +1 more source

Identification of Active Compounds of Centipeda minima for Potentiating Tumor Immunotherapy in Non‐Small Cell Lung Cancer via FANCD2‐cGAS/STING/IFN‐I Signaling Axis

open access: yesPhytotherapy Research, EarlyView.
Schematic diagram illustrating the underlying mechanisms by which ECM and its active components activate the FANCD2‐cGAS/STING/IFN‐I signaling axis, thus enhancing the therapeutic efficacy of anti‐PD‐1 in NSCLC. ABSTRACT Activation of cGAS/STING/IFN‐I signaling pathway serves as a potential therapeutic strategy to enhance CD8+ T cells infiltration and ...
Han‐Chen Wang   +9 more
wiley   +1 more source

Assessments as Sites for Teacher Sensemaking About Epistemic Learning Goals in Science

open access: yesScience Education, EarlyView.
ABSTRACT Recent science education reforms aim to broaden allowable ways of knowing and learning in science classes. Doing so requires that we attend to and work to shift messages about useful ways to know and learn (i.e., epistemological messages) embedded in course designs and enactments.
Lindsay B. Wells   +2 more
wiley   +1 more source

Perinatal Western-style diet exposure associated with decreased microglial counts throughout the arcuate nucleus of the hypothalamus in Japanese macaques.

open access: yesJ Neurophysiol
Papadakis S   +8 more
europepmc   +1 more source

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