The iPP Printing Paradox: Interlayer Adhesion Through Crystallization
In fused filament fabrication of isotactic polypropylene, high molecular weight and a high print speed increase the shear during deposition. This shear promotes the formation of the ductile β‐phase at the interphase, which improves interlayer adhesion, as shown by an eightfold increase in fracture energy measured via a T‐peel test on two printed ...
Paul M. H. van Heugten +5 more
wiley +1 more source
The Long Trajectory of Rubber Physics: 3500+ Years and Counting
Natural rubber's trajectory is traced from Mesoamerican use of Castilla elastica through vulcanization and the pneumatic tire to macromolecular physics and modern solid‐state refrigeration. Illustrations of C. elastica and an H. brasiliensis plantation frame the historical progression from indigenous material, then industrial crop and on to advanced ...
Gregory B. McKenna
wiley +1 more source
Gentiopicroside Regulates EGFR and Induces Its Lysosomal Degradation to Attenuate Heart Failure
GPS attenuates pressure overload‐induced cardiac remodeling by promoting lysosomal degradation of EGFR. TAC‐induced EGFR accumulation activates AKT/ERK1/2 signaling and drives pathological cardiac hypertrophy, fibrosis, apoptosis, oxidative stress, and cardiac dysfunction. GPS promotes lysosome‐dependent EGFR degradation, thereby limiting excessive AKT/
Mingzhen Cao +6 more
wiley +1 more source
Schematic diagram illustrating the underlying mechanisms by which ECM and its active components activate the FANCD2‐cGAS/STING/IFN‐I signaling axis, thus enhancing the therapeutic efficacy of anti‐PD‐1 in NSCLC. ABSTRACT Activation of cGAS/STING/IFN‐I signaling pathway serves as a potential therapeutic strategy to enhance CD8+ T cells infiltration and ...
Han‐Chen Wang +9 more
wiley +1 more source
Assessments as Sites for Teacher Sensemaking About Epistemic Learning Goals in Science
ABSTRACT Recent science education reforms aim to broaden allowable ways of knowing and learning in science classes. Doing so requires that we attend to and work to shift messages about useful ways to know and learn (i.e., epistemological messages) embedded in course designs and enactments.
Lindsay B. Wells +2 more
wiley +1 more source
Low-frequency electroacupuncture exerts antinociceptive effects through activation of POMC neural circuit induced endorphinergic input to the periaqueductal gray from the arcuate nucleus. [PDF]
Wang Q +7 more
europepmc +1 more source
Long-term Recordings of Arcuate Nucleus Kisspeptin Neurons Across the Mouse Estrous Cycle.
Vas S +5 more
europepmc +1 more source
Erratum: Roux-En-Y Gastric Bypass Improves Insulin Sensitivity in Obese Rats with Type 2 Diabetes Mellitus by Regulating the Grin3a/AMPK Signal Axis in Hypothalamic Arcuate Nucleus [Corrigendum]. [PDF]
europepmc +1 more source

