Results 61 to 70 of about 3,051,240 (335)

Devil's Staircase -- Rotation Number of Outer Billiard with Polygonal Invariant Curves [PDF]

, 2014
In this paper, we discuss rotation number on the invariant curve of a one parameter family of outer billiard tables. Given a convex polygon $\eta$, we can construct an outer billiard table $T$ by cutting out a fixed area from the interior of $\eta$.
Yao, Zijian
core  

Inhibiting stearoyl‐CoA desaturase suppresses bone metastatic prostate cancer by modulating cellular stress, mTOR signaling, and DNA damage response

FEBS Letters, EarlyView.
Bone metastasis in prostate cancer (PCa) patients is a clinical hurdle due to the poor understanding of the supportive bone microenvironment. Here, we identify stearoyl‐CoA desaturase (SCD) as a tumor‐promoting enzyme and potential therapeutic target in bone metastatic PCa.
Alexis Wilson, Mackenzie K Herroon, Shane Mecca, Laimar C Garmo, Jacob Lindquist, Shrila Rajendran, Steve M. Patrick, Izabela Podgorski   +7 more
wiley   +1 more source

Receiver operating characteristic curve

Current Medicine Research and Practice, 2012
A receiver operating characteristic (ROC) curve is a plot of tradeoff between sensitivity and specificity. It is a plot that evaluates a diagnostic test for a continuous variable between diseased and non-diseased subjects.
Anita Singh, Vivek Choudhury, Satish Saluja   +2 more
doaj  

Impact of Sampling Strategy and Population Model on Bayesian Estimates of Vancomycin AUC in Patients with BMI > 40 kg/m²: A Single-Center Retrospective Study

Medicines
Background/Objectives: Growing evidence supports the use of a single trough concentration, rather than both a peak and trough, to estimate the 24 h area under the curve (AUC24) of vancomycin using Bayesian software (InsightRx® Ver.1.71).
Sarah A. Ekkelboom, Soraya M. Hobart, Laurie J. Barten, Staci L. Hemmer   +3 more
doaj   +1 more source

Serum vitamin D is a biomolecular biomarker for proliferative diabetic retinopathy

International Journal of Retina and Vitreous, 2019
Background Vitamin D is a multi-functional fat-soluble metabolite essential for a vast number of physiological processes. Non-classical functions are gaining attention because of the close association of vitamin D deficiency with diabetes, and its ...
Gauhar Nadri, Sandeep Saxena, Abbas Ali Mahdi, Apjit Kaur, Md. Kaleem Ahmad, Pragati Garg, Carsten H. Meyer   +6 more
doaj   +1 more source

Comparative assessment of three common algorithms for estimating the variance of the area under the nonparametric receiver operating characteristic curve [PDF]

The area under the receiver operating characteristic (ROC) curve is often used to summarize and compare the discriminatory accuracy of a diagnostic test or modality,and to evaluate the predictive power of statistical models for binary outcomes ...
Mario A. Cleves
core   +1 more source

Wilson Loops and Minimal Surfaces Beyond the Wavy Approximation

, 2015
We study Euclidean Wilson loops at strong coupling using the AdS/CFT correspondence, where the problem is mapped to finding the area of minimal surfaces in Hyperbolic space.
Dekel, Amit
core   +1 more source

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

FEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee, Dimitrios Bekiari, Sofia Doello, Karl Forchhammer   +3 more
wiley   +1 more source

Predicted Area Under the Curve Infinity by Dose [PDF]

, 2020
National Cancer Institute
openalex   +1 more source

PARP inhibitors elicit distinct transcriptional programs in homologous recombination competent castration‐resistant prostate cancer

Molecular Oncology, EarlyView.
PARP inhibitors are used to treat a small subset of prostate cancer patients. These studies reveal that PARP1 activity and expression are different between European American and African American prostate cancer tissue samples. Additionally, different PARP inhibitors cause unique and overlapping transcriptional changes, notably, p53 pathway upregulation.
Moriah L. Cunningham, Jasibel Vasquez‐Gonzalez, Samantha M. Barnada, Salome Tchotorlishvili, Latese Jones, Ryan Maguire, Genevieve Lewis, Kinza Rizwan, Jenny Deng, Salma Koachar, Drithi Patel, Hailey Shankle, Tessa Mulders, Namra Ajmal, Charalambos Solomides, Emad S. Alnemri, Teresa F. Alnemri, Ayesha A. Shafi, Leonard G. Gomella, Wm Kevin Kelly, Steven B. McMahon, Matthew J. Schiewer   +21 more
wiley   +1 more source