Results 61 to 70 of about 1,295,849 (308)
COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells
Molecular Oncology, EarlyView.This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos +6 more
wiley +1 more source
Receiver operating characteristic curve
Current Medicine Research and Practice, 2012 A receiver operating characteristic (ROC) curve is a plot of tradeoff between sensitivity and specificity. It is a plot that evaluates a diagnostic test for a continuous variable between diseased and non-diseased subjects.
Anita Singh +2 more
doaj
MedicinesBackground/Objectives: Growing evidence supports the use of a single trough concentration, rather than both a peak and trough, to estimate the 24 h area under the curve (AUC24) of vancomycin using Bayesian software (InsightRx® Ver.1.71).
Sarah A. Ekkelboom +3 more
doaj +1 more source
On splitting the area under curves II
Journal of Differential Equations, 1982 AbstractThis paper continues the author's work [3, S. Minsker, J. Differential Equations, 26, No. 3 (1977), 443–457.] on an area-splitting problem leading to the functional differential equation a′(a(x)) = a(x)x. This equation is dealt with by transforming it into the linear equation ψ′(x) = ψ(x + c), for which positive solutions on (−∞, −c) are sought.
openaire +1 more source
Molecular Oncology, EarlyView.Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau +36 more
wiley +1 more source
Area under receiver operating curve.
, 2019 Area under receiver operating curve.
Brian Mullin (6376964) +6 more
core +1 more source
Area under the curve for HFGTT.
, 2020 Total Area Under the Curve (AUCT) for plasma triglycerides (A), glucose (B), and insulin (C); Incremental Area Under the Curve (AUCI)for plasma triglycerides (D), glucose (E), and insulin (F) during the HFGTT.
Anthony S. Wolfe (8407707) +4 more
core +1 more source
Interrogating the immune landscape of microsatellite stable RAS‐mutated colon cancer
Molecular Oncology, EarlyView.COLOSSUS project RAS‐mutated MSS colon cancer study explored transcriptomics and immune cell density by immunohistochemistry (IHC), Immunoscore (IS), ISIC/TuLIS scores, mutation counts, and detected different prevalences but similar microenvironment composition across immune markers with clinical relevance for future immunotherapy combination ...
Rodrigo Dienstmann +61 more
wiley +1 more source
Part 5: Receiver Operating Characteristic Curve and Area under the Curve
Emergency, 2016 Multiple diagnostic tools are used by emergency physicians,every day. In addition, new tools are evaluated to obtainmore accurate methods and reduce time or cost of conventionalones.
Saeed Safari +3 more
doaj