Results 231 to 240 of about 15,186,604 (295)

Integrating Lymph Node Metastasis and Programmed Death-Ligand 1 Prediction in Non-Small Cell Lung Cancer From a Single PET/CT Scan: Multicenter Radiomics Study. [PDF]

JMIR Med Inform
Chen W, Liu Q, Peng H, Zhang J, Chen Z, Hu S, Song S.   +6 more
europepmc   +1 more source

Ahcy Acts as an Effector of Hnf4a‐Driven Super‐Enhancer Activation to Alleviate MASLD During Intermittent Fasting

Advanced Science, EarlyView.
Our study identifies an Hnf4a‐driven super‐enhancer of hepatic Ahcy that mediates the protective effects of intermittent fasting against MASLD. Disruption of the Ahcy super‐enhancer reduces Ahcy expression and exacerbates lipid accumulation. This pathway prevents aberrant promoter hypermethylation by maintaining the SAM/SAH balance, as exemplified by ...
Huafeng Chen, Shilin Zhang, Xiaojie Deng, Wenqiang Xie, Fen Xu, Jie Shen, Hua Liang   +6 more
wiley   +1 more source

Skill-File-Guided Virtual Screening: A Single-Target Formyl Peptide Receptor 2 Case Study of Large-Language-Model-Coordinated Physics and Diffusion Docking. [PDF]

Comput Struct Biotechnol J
Gani O.
europepmc   +1 more source

Intratumoral Hypoxia Triggers Mitochondrial BHLHE40 ROS Sensing Pathway to Promote Radioresistance in Triple‐Negative Breast Cancer

Advanced Science, EarlyView.
Hypoxia triggers a dual mechanism for BHLHE40 upregulation: reactive oxygen species (ROS)‐dependent post‐translational modification and hypoxia‐inducible factor (HIF)‐dependent transcriptional activation. Under hypoxic conditions, mitochondrial BHLHE40 accumulates and senses ROS via cysteine thiol oxidation and disulfide‐linked homodimer formation ...
Jia Liu, Ziliang Nie, Xi Chen, Guangyu Ji, Yajing Zhang, Zhiqun Zhao, Yuhong Zhang, Xinlong Du, Zhenzhen Zhou, Jiayi Li, Yaozong Yang, Fengqi Sun, Zhibo Yan, Haiquan Lu   +13 more
wiley   +1 more source

Correction to "Early Acute-Phase Energy Intake Is Independently Associated With Swallowing Decline in Older Patients With Aspiration Pneumonia: A Retrospective Cohort Study". [PDF]

Geriatr Gerontol Int
europepmc   +1 more source

Predicting in-hospital mortality after cardiac surgery using machine learning: temporal validation in the MIMIC-IV database. [PDF]

Front Cardiovasc Med
Zhou J, Zhang C.
europepmc   +1 more source

Bending‐Stable Pressure Sensor Based on Natural Wood Nanofibers for Ultra‐Low Detection Limit

Advanced Science, EarlyView.
A wood nanofiber‐based flexible pressure sensor with intrinsic bending‐stable performance is developed through a porous electrospun architecture and interdigital electrode design. The device exhibits an ultra‐low detection limit and stable operation under deformation for physiological monitoring and spatial sensing, providing a sustainable strategy for
Xu Zeng, Zhengnan Sun, Yilin Wang, Yao Tan, Ranran Xu, Beomjoon Kim, Juergen Brugger, Xiaosheng Zhang   +7 more
wiley   +1 more source

Predicting the Current Potential Suitable Habitat of <i>Pinus tabuliformis</i> in China Using Multi-Source Environmental Data and Ensemble Learning Models. [PDF]

Ecol Evol
Ding H, Meng J, Zhang Y, Yang Y, Deng W, Xu D.   +5 more
europepmc   +1 more source