Results 251 to 260 of about 474,933 (300)

NMI Regulates Adipose Adaptive Thermogenesis Through TLR4/IRF3 Signaling to Promote Obesity

Advanced Science, EarlyView.
Adipose tissue‐derived NMI is secreted under metabolic stress and suppresses adaptive thermogenesis through TLR4/IRF3 signaling, repressing the PPARα/PGC‐1α/UCP1 thermogenic transcriptional program. Genetic ablation or anti ‐ NMI monoclonal antibody treatment enhances energy expenditure, protects against DIO, and ameliorates adipose tissue inflammation,
Ting‐Ting Li, Xin‐Yuan Zhao, Min Zhang, Zhuang‐Feng Weng, Xiao‐Ran Guo, Ying‐Fang Liu, Qiao‐Ping Wang, Huan‐Huan Liang   +7 more
wiley   +1 more source

Prediction of delayed graft function after deceased donor kidney transplantation: development and temporal validation in a single-center cohort. [PDF]

BMC Nephrol
Feng R, Liao G, Zhong B, Zhou W, Kou Z, Li Y, Hu J, Huang Y, Liu Y.   +8 more
europepmc   +1 more source

De Novo Design of Membrane‐Targeting Antimicrobial Peptides Against Gram‐Negative Bacteria Using a Generative Artificial Intelligence Framework

Advanced Science, EarlyView.
Antimicrobial resistance caused by Gram‐negative bacteria remains difficult to overcome due to the protective outer membrane. To address this challenge, a multi‐condition constrained generative AI framework, GenMTAMP is proposed for de novo membrane‐targeting antimicrobial peptide design by integrating physicochemical and spatial structure descriptors.
Jingxiao Yu, Da‐Wen Sun, QingYi Wei, Yibing Zhang, Jidong Tang, Hongbin Pu   +5 more
wiley   +1 more source

No effects of respiratory muscle endurance exercises on postprandial glucose excursions. [PDF]

Front Sports Act Living
Beltrami FG, Mullarkey J, Spengler CM.
europepmc   +1 more source

The performance ceiling: why clinical data is insufficient for precision prognosis in concussion. [PDF]

Front Neurol
Napora Z, Griffith O, Slobounov S.
europepmc   +1 more source

Urine protein electrophoresis analysis in dogs with systemic inflammatory response syndrome. [PDF]

J Vet Intern Med
Jung R, Bae H, Cho KW, Park J, Yu DH.
europepmc   +1 more source

A plasma protein signature for cerebral amyloid angiopathy. [PDF]

Acta Neuropathol
Singh A, Denkinger MN, Leuzy A, Dieckhoff K, Liu J, Marques TM, Monuki E, Stark C, Grill JD, Hom C, Sultzer D, Doran E, Lott I, Wood K, Gawronski B, Gonzalez L, Choudhury P, Atri A, Beach TG, Serrano GE, Sajjadi SA, Van Keuren-Jensen K, Reiman EM, Head E, Ashton NJ.   +24 more
europepmc   +1 more source

A multimodal deep learning model for predicting impending rupture in symptomatic abdominal aortic aneurysms using CTA and clinical data. [PDF]

Front Cardiovasc Med
Cheng J, Wang S, Zhang Z, Gu R, Wu X, Wang Y, Sun Y, Wang N, Wang X, Yu H.   +9 more
europepmc   +1 more source

Histopathological Assessment of Myocardial Ischemia-Reperfusion Injury Using Transformer-Based Artificial Intelligence: Model Comparison Study. [PDF]

JMIR Med Inform
Liu C, Xu M, Lv Y, Zhu Z, Pan Y, Wang Y.
europepmc   +1 more source