Results 1 to 10 of about 36,753 (202)

Quantification of thermal dose in moderate clinical hyperthermia with radiotherapy: a relook using temperature–time area under the curve (AUC) [PDF]

International Journal of Hyperthermia, 2021
Background Thermal dose in clinical hyperthermia reported as cumulative equivalent minutes (CEM) at 43 °C (CEM43) and its variants are based on direct thermal cytotoxicity assuming Arrhenius ‘break’ at 43 °C.
Niloy R. Datta, Dietmar Marder, Sneha Datta, Andreas Meister, Emsad Puric, Emanuel Stutz, Susanne Rogers, Brigitte Eberle, Olaf Timm, Michal Staruch, Oliver Riesterer, Stephan Bodis   +11 more
doaj   +4 more sources

ImbTreeAUC: An R package for building classification trees using the area under the ROC curve (AUC) on imbalanced datasets

SoftwareX, 2021
In this paper, we propose a novel R package, named ImbTreeAUC, for building binary and multiclass decision tree using the area under the receiver operating characteristic (ROC) curve.
Krzysztof Gajowniczek, Tomasz Ząbkowski
doaj   +4 more sources

Evaluation of a Novel Glucose Area Under the Curve (AUC) Monitoring System: Comparison with the AUC by Continuous Glucose Monitoring [PDF]

Diabetes & Metabolism Journal, 2016
BackgroundManagement of postprandial hyperglycemia is a key aspect in diabetes treatment. We developed a novel system to measure glucose area under the curve (AUC) using minimally invasive interstitial fluid extraction technology (MIET) for simple ...
Satoshi Ugi, Hiroshi Maegawa, Katsutaro Morino, Yoshihiko Nishio, Toshiyuki Sato, Seiki Okada, Yasuo Kikkawa, Toshihiro Watanabe, Hiromu Nakajima, Atsunori Kashiwagi   +9 more
doaj   +3 more sources

Candidates for area under the concentration–time curve (AUC)-guided dosing and risk reduction based on analyses of risk factors associated with nephrotoxicity in vancomycin-treated patients

Journal of Global Antimicrobial Resistance, 2021
: Objectives: : Compared with vancomycin trough concentration (Cmin)-guided dosing, area under the concentration–time curve (AUC)-guided dosing is associated with decreased acute kidney injury (AKI).
Naoto Hashimoto, Toshimi Kimura, Yukihiro Hamada, Takashi Niwa, Yuki Hanai, Masayuki Chuma, Satoshi Fujii, Kazuaki Matsumoto, Akari Shigemi, Hideki Kawamura, Yoshiko Takahashi, Yoshio Takesue   +11 more
doaj   +3 more sources

Predicting the Area under the Plasma Concentration-Time Curve (AUC) for First Dose Vancomycin Using First-Order Pharmacokinetic Equations

Antibiotics, 2023
To treat critically ill patients, early achievement of the target area under the plasma concentration-time curve/minimum inhibitory concentration (AUC/MIC) in the first 24 h is recommended.
Kritsaporn Sujjavorakul, Wasan Katip, Stephen J. Kerr, Noppadol Wacharachaisurapol, Thanyawee Puthanakit   +4 more
doaj   +3 more sources

Transforming the Area under the Normal Curve (AUC) into Cohen’s d, Pearson’s r pb , Odds-Ratio, and Natural Log Odds-Ratio: Two Conversion Tables

European Journal of Psychology Applied to Legal Context, 2018
The importance of the area under the normal curve (AUC) as a measure of the effect size (ES) in applied and forensic research has been highlighted in several articles and Tables for converting the AUC curve into Pearson’s rpb and Cohen’s d have been ...
Jesús F. Salgado
doaj   +2 more sources

The Matthews correlation coefficient (MCC) should replace the ROC AUC as the standard metric for assessing binary classification

BioData Mining, 2023
Binary classification is a common task for which machine learning and computational statistics are used, and the area under the receiver operating characteristic curve (ROC AUC) has become the common standard metric to evaluate binary classifications in ...
Davide Chicco, Giuseppe Jurman
doaj   +1 more source

A Novel Linear Classifier for Class Imbalance Data Arising in Failure-Prone Air Pressure Systems

IEEE Access, 2021
An Air Pressure System (APS) is one of the crucial components of an automobile. Its failure leads to financial loses, and it may lead to loss of lives. Thus predicting such failure is a critical problem that requires a rigorous solution.
Mujahid N. Syed, Md. Rafiul Hassan, Irfan Ahmad, Mohammad Mehedi Hassan, Victor Hugo C. De Albuquerque   +4 more
doaj   +1 more source

Naringenin alters the pharmacokinetics of ranolazine in part through the inhibition of cytochrome P450 (3A4) and P-glycoprotein

Future Journal of Pharmaceutical Sciences, 2023
Background This study set out to look at how naringenin affected the pharmacokinetics of ranolazine in rats. The pharmacokinetic investigation of ranolazine in rats following oral administration of ranolazine with or without coadministration of ...
Faisal Alotaibi
doaj   +1 more source

Inference about time-dependent prognostic accuracy measures in the presence of competing risks

BMC Medical Research Methodology, 2020
Background Evaluating a candidate marker or developing a model for predicting risk of future conditions is one of the major goals in medicine. However, model development and assessment for a time-to-event outcome may be complicated in the presence of ...
Rajib Dey, Giada Sebastiani, Paramita Saha-Chaudhuri   +2 more
doaj   +1 more source