Results 1 to 10 of about 423,872 (249)

Evaluation of a Novel Glucose Area Under the Curve (AUC) Monitoring System: Comparison with the AUC by Continuous Glucose Monitoring [PDF]

Diabetes & Metabolism Journal, 2016
BackgroundManagement of postprandial hyperglycemia is a key aspect in diabetes treatment. We developed a novel system to measure glucose area under the curve (AUC) using minimally invasive interstitial fluid extraction technology (MIET) for simple ...
Satoshi Ugi, Hiroshi Maegawa, Katsutaro Morino, Yoshihiko Nishio, Toshiyuki Sato, Seiki Okada, Yasuo Kikkawa, Toshihiro Watanabe, Hiromu Nakajima, Atsunori Kashiwagi   +9 more
doaj   +4 more sources

Quantification of thermal dose in moderate clinical hyperthermia with radiotherapy: a relook using temperature–time area under the curve (AUC) [PDF]

International Journal of Hyperthermia, 2021
Background Thermal dose in clinical hyperthermia reported as cumulative equivalent minutes (CEM) at 43 °C (CEM43) and its variants are based on direct thermal cytotoxicity assuming Arrhenius ‘break’ at 43 °C.
Niloy R. Datta, Dietmar Marder, Sneha Datta, Andreas Meister, Emsad Puric, Emanuel Stutz, Susanne Rogers, Brigitte Eberle, Olaf Timm, Michal Staruch, Oliver Riesterer, Stephan Bodis   +11 more
doaj   +5 more sources

ImbTreeAUC: An R package for building classification trees using the area under the ROC curve (AUC) on imbalanced datasets

SoftwareX, 2021
In this paper, we propose a novel R package, named ImbTreeAUC, for building binary and multiclass decision tree using the area under the receiver operating characteristic (ROC) curve.
Krzysztof Gajowniczek, Tomasz Ząbkowski
doaj   +4 more sources

1570. Association Between Vancomycin Area Under the Curve (AUC) and Nephrotoxicity [PDF]

Open Forum Infect Dis, 2019
Abstract Background It is unclear whether increased vancomycin area under the curve (AUC) contributes to acute kidney injury (AKI) risk. Methods This retrospective cohort study was undertaken to determine whether vancomycin AUC > ...
Poston-Blahnik A, Moenster R.
europepmc   +3 more sources

Evaluating the Safety of Trough Versus Area Under the Curve (AUC)-Based Dosing Method of Vancomycin With Concomitant Piperacillin-Tazobactam. [PDF]

J Pharm Technol, 2022
Background: Vancomycin and piperacillin-tazobactam (VPT) is a common antibiotic combination used in hospitals, and there has been increasing data indicating that the combination is associated with increased rates of acute kidney injury (AKI). It is unclear if the dosing method of vancomycin would mitigate the risk of AKI seen with VPT.
Karas C, Manning K, Childress DT, Covington EW, Manis MM.   +4 more
europepmc   +3 more sources

Analysis of the Area Under a Curve (AUC) using C-programming: Trapezium and Simpson rules techniques.

Journal of ICT in Education, 2022
This study aimed to analyze the Area Under a Curve (AUC) using C-programming i.e. Trapezium and Simpson rules. There are various mathematical methods that can be applied to solve numerical integration for different data spaces.
Ainul Nadira Tuah, Abu Bakar Ibrahim, Sumayyah Dzulkifly, Fauzi Mohammad Yusof, Ramli Awang Nor, Razali Ariffin   +5 more
doaj   +2 more sources

Characteristics and calculations of paired vancomycin measurements for determination of 24-h area-under-curve (AUC)

Practical Laboratory Medicine, 2023
Current pharmacy practice guidelines recommend 24-h area-under-curve (AUC24) targets for use of vancomycin against methicillin-resistant Staphylococcus aureus (MRSA). AUC protocol-specific vancomycin orders were begun recently (2022) at our institution.
Yutao Deng, Zachary W. Rebollido, Matthew A. Pettengill, Douglas F. Stickle   +3 more
openaire   +5 more sources

Candidates for area under the concentration–time curve (AUC)-guided dosing and risk reduction based on analyses of risk factors associated with nephrotoxicity in vancomycin-treated patients

Journal of Global Antimicrobial Resistance, 2021
: Objectives: : Compared with vancomycin trough concentration (Cmin)-guided dosing, area under the concentration–time curve (AUC)-guided dosing is associated with decreased acute kidney injury (AKI).
Naoto Hashimoto, Toshimi Kimura, Yukihiro Hamada, Takashi Niwa, Yuki Hanai, Masayuki Chuma, Satoshi Fujii, Kazuaki Matsumoto, Akari Shigemi, Hideki Kawamura, Yoshiko Takahashi, Yoshio Takesue   +11 more
doaj   +3 more sources

Predicting the Area under the Plasma Concentration-Time Curve (AUC) for First Dose Vancomycin Using First-Order Pharmacokinetic Equations

Antibiotics, 2023
To treat critically ill patients, early achievement of the target area under the plasma concentration-time curve/minimum inhibitory concentration (AUC/MIC) in the first 24 h is recommended.
Kritsaporn Sujjavorakul, Wasan Katip, Stephen J. Kerr, Noppadol Wacharachaisurapol, Thanyawee Puthanakit   +4 more
doaj   +3 more sources

1391. Vancomycin Area Under the Curve (AUC) to Predict Nephrotoxicity: A Systematic Review and Meta-Analysis of Observational Studies [PDF]

Open Forum Infect Dis, 2018
Abstract Background Recent studies have proposed monitoring vancomycin area under the curve (AUC) as a more precise method of attaining goal exposures compared with trough monitoring. Different dosing methods and different exposure-toxicity thresholds have been proposed. Therefore, we aimed to analyze
Aljefri D, Avedissian S, Rhodes N, Postelnick M, Scheetz M.   +4 more
europepmc   +3 more sources