Results 41 to 50 of about 127,696,973 (248)

A Pipeline-based Framework for Early Prediction of Diabetes [PDF]

مجله انفورماتیک سلامت و زیست پزشکی, 2023
Introduction: Diabetes is a chronic disease worldwide, with an increasing annual death rate. Many health professionals seek innovative ways to detect and treat it early. Rapid advances in machine learning have improved disease diagnosis. However, because
Karlo Abnoosian, Rahman Farnoosh, Mohammad Hassan Behzadi   +2 more
doaj  

Spatial and single‐nuclei transcriptomics reveals idiosyncratic and generic patterns in papillary and anaplastic thyroid cancers

Molecular Oncology, EarlyView.
Matched spatial transcriptomics and single‐nuclei RNA‐seq were generated for anaplastic and BRAFV600E papillary thyroid cancers revealing generic and tumor‐specific states occurring in cancer cells and in the tumor microenvironment. In this context, cancer dedifferentiation mirrored organoid maturation through ordered thyroid marker gain/loss ...
Adrien Tourneur, Joel Rodrigues Vitória, Manuel Saiselet, Ligia Craciun, Denis Larsimont, Anne Lefort, Frédérick Libert, Carine Maenhaut, Sabine Costagliola, Maxime Tarabichi, Mirian Romitti, Vincent Detours   +11 more
wiley   +1 more source

Circulating microRNA signatures of cachexia and cancer in Canis familiaris as a comparative oncology model for human disease

Molecular Oncology, EarlyView.
Circulating microRNAs as biomarkers of cachexia and sex‐specific cancer in senior dogs. In 25 client‐owned dogs, four circulating miRNAs (miR‐15a, miR‐15b, miR‐16, miR‐140) were downregulated in cachexia, with miR‐16 the strongest individual biomarker (AUC = 0.899).
Soon‐Seok Park, Kyongman An, Gyeonghwa Kim, Soo‐Nyun Choi, Hong‐Ki Lee, Keun Hur, Kyu‐Shik Jeong   +6 more
wiley   +1 more source

Area under Curve (AUC) comparison.

, 2013
Area under Curve (AUC) comparison measuring the ability of recovering the original PPI networks: (a) Y_Tong, (b) H_Bind, (c) H_InAct, (d) F_BioGrid, (e) H_BioGrid using embedding space dimensions of 1 to 20.
Lin Zhu (192179), De-Shuang Huang (396909), Zhu-Hong You (396908), Bing Wang (126120)   +3 more
core   +1 more source

Receiver operating characteristic curve

Current Medicine Research and Practice, 2012
A receiver operating characteristic (ROC) curve is a plot of tradeoff between sensitivity and specificity. It is a plot that evaluates a diagnostic test for a continuous variable between diseased and non-diseased subjects.
Anita Singh, Vivek Choudhury, Satish Saluja   +2 more
doaj  

Dual therapeutic interventions to optimize vancomycin exposure and reduce nephrotoxicity: a cohort study from a single center

BMC Nephrology
Background Vancomycin-associated Acute Kidney Injury (AKI) is a significant global concern, increasing healthcare costs, morbidity, and mortality. This Quality Improvement Project (QIP) aimed to reduce supratherapeutic vancomycin concentrations and AKI ...
Janice Xuanhui Li, Horng-Ruey Chua, Gladys Wei-Teng Chung, Jyoti Somani, Yi Da   +4 more
doaj   +1 more source

Epigenetic silencing of the liver‐specific lncRNA LUNAR promotes liver cancer progression via NOTCH activation

Molecular Oncology, EarlyView.
LUNAR is a liver‐specific long noncoding RNA (lncRNA) that is highly expressed in normal liver but becomes epigenetically silenced in hepatocellular carcinoma through promoter hypermethylation. Loss of LUNAR is associated with NOTCH activation, epithelial–mesenchymal transition, and metastasis, whereas restoring LUNAR restrains metastatic progression ...
Se Ha Jang, Hyung Seok Kim, Geum Ok Baek, Moon Gyeong Yoon, Su In Lee, Jee‐Yeong Jeong, Ji Eun Han, Soon Sun Kim, Jae Youn Cheong, Jung Woo Eun   +9 more
wiley   +1 more source

Evaluation of everolimus pharmacokinetic monitoring based on trough concentration and area under the blood concentration time curve in kidney transplantation

BMC Nephrology
Background Everolimus (EVR) is widely used in kidney transplantation; however, the optimal sampling time point for therapeutic drug monitoring and the relationship between EVR exposure and adverse events under tacrolimus-based regimens remain unclear ...
Shota Fukae, Yoichi Kakuta, Soichi Matsumura, Ryo Tanaka, Masataka Kawamura, Shigeaki Nakazawa, Norio Nonomura   +6 more
doaj   +1 more source

Predictive and prognostic biomarkers of Bacillus Calmette‐Guérin therapy failure in bladder cancer patients: A systematic review

Molecular Oncology, EarlyView.
High‐risk bladder cancer is typically treated with Bacillus Calmette‐Guérin (BCG), but 30–40% of patients relapse. No FDA‐ or CE‐approved biomarkers currently predict or prognosticate BCG failure. We systematically reviewed the literature and identified 72 eligible studies, revealing several promising biomarkers associated with BCG treatment response ...
Rui Ribeiro‐Pereira, Ana Teixeira‐Marques, Rui Freitas, João A Carvalho, Sara Monteiro‐Reis, Giorgio I. Russo, Rui Henrique, Carmen Jerónimo   +7 more
wiley   +1 more source

Receiver operating characteristic (ROC) curve and area under the curve (AUC) to evaluation the performance of the assay.

, 2021
Receiver operating characteristic (ROC) curve and area under the curve (AUC) to evaluation the performance of the assay.
Tianyang Xu (1532233), Aiguo Zhang (352314), Eric Chu (3271182), Dayu Zhang (710629), Jinwei Du (11378846), Michael Y. Sha (2401549)   +5 more
core   +1 more source