Results 21 to 30 of about 423,872 (249)

Evaluation of the Methods for Nonlinear Analysis of Heart Rate Variability

Fractal and Fractional, 2023
The dynamics of cardiac signals can be studied using methods for nonlinear analysis of heart rate variability (HRV). The methods that are used in the article to investigate the fractal, multifractal and informational characteristics of the intervals ...
Evgeniya Gospodinova, Penio Lebamovski, Galya Georgieva-Tsaneva, Mariya Negreva   +3 more
doaj   +1 more source

Prequential AUC: properties of the area under the ROC curve for data streams with concept drift

Knowledge and Information Systems, 2017
Modern data-driven systems often require classifiers capable of dealing with streaming imbalanced data and concept changes. The assessment of learning algorithms in such scenarios is still a challenge, as existing online evaluation measures focus on efficiency, but are susceptible to class ratio changes over time. In case of static data, the area under
Dariusz Brzezinski, Jerzy Stefanowski
openaire   +1 more source

Can First-Dose Therapeutic Drug Monitoring Predict the Steady State Area Under the Blood Concentration-Time Curve of Busulfan in Pediatric Patients Undergoing Hematopoietic Stem Cell Transplantation?

Frontiers in Pediatrics, 2022
Busulfan has high intra-individual variability and possible time-dependent changes in clearance, which complicates therapeutic drug monitoring (TDM), as first dose sampling may not predict the steady state concentrations.
Abdullah Alsultan, Abdullah Alsultan, Ahmed A. Albassam, Abdullah Alturki, Abdulrahman Alsultan, Abdulrahman Alsultan, Mohammed Essa, Mohammed Essa, Mohammed Essa, Bader Almuzzaini, Salman Alfadhel   +10 more
doaj   +1 more source

Incidence and Severity of Carboplatin‐Associated Hearing Loss in Children With Cancer Assessed by the SIOP Boston 2012 Ototoxicity Criteria

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Platinum‐based chemotherapy is known to cause severe and debilitating hearing loss, but unlike cisplatin, the true incidence of carboplatin‐induced hearing loss remains unclear. We evaluated functional hearing outcomes in children receiving carboplatin to determine the incidence and severity of ototoxicity. Procedure We identified a
Aniket Chawla, Sean Carter, Andrew Wood, Sandra Staffieri, Andrew Dodgshun, David D. Eisenstat, Michael Sullivan   +6 more
wiley   +1 more source

Nonparametric bootstrap methods for interval estimation of the area under the ROC curve with correlated diagnostic test data: application to whole-virus ELISA testing in swine

Frontiers in Veterinary Science, 2023
Developing and evaluating novel diagnostic assays are crucial components of contemporary diagnostic research. The receiver operating characteristic (ROC) curve and the area under the ROC curve (AUC) are frequently used to evaluate diagnostic assays ...
Jinji Pang, Jinji Pang, Wangqian Ju, Michael Welch, Phillip Gauger, Peng Liu, Qijing Zhang, Chong Wang, Chong Wang   +8 more
doaj   +1 more source

Association Between Individualized Education for Kidney Replacement Therapy Modality Selection and Peritoneal Dialysis Initiation: A Cross‐Sectional Study

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Introduction Peritoneal dialysis (PD) is an established home‐based kidney replacement therapy (KRT), but its uptake remains low in Japan. We evaluated whether individualized education in a dedicated outpatient clinic was associated with the initiation of PD.
Yasuko Ito, Ryuichi Yoshimura, Takaki Yamauchi, Yuta Funakoshi, Hirotaka Sonoda, Seiji Kobayashi, Hiroyuki Terawaki, Takafumi Ito   +7 more
wiley   +1 more source

Towards non-invasive diagnosis of glioblastoma: identifying metabolic biomarkers in liquid biopsies using a ROC-based approach

Discover Oncology
For over seven decades, the World Health Organization (WHO) has classified central nervous system tumors primarily based on histological criteria. While recent updates have incorporated molecular genetics and histochemistry, this approach still overlooks
Margareth Borges Coutinho Gallo
doaj   +1 more source

Comparing the Relative Efficacy of Generalized Estimating Equations, Latent Growth Curve Modeling, and Area Under the Curve with a Repeated Measures Discrete Ordinal Outcome Variable

Stats
Researchers are often interested in how changes in one variable influence changes in a second variable, requiring the repeated measures of two variables.
Daniel Rodriguez, Ryan Verma, Juliana Upchurch   +2 more
doaj   +1 more source

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

FEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee, Dimitrios Bekiari, Sofia Doello, Karl Forchhammer   +3 more
wiley   +1 more source

A molecular computational model improves the preoperative diagnosis of thyroid nodules

BMC Cancer, 2012
Background Thyroid nodules with indeterminate cytological features on fine needle aspiration (FNA) cytology have a 20% risk of thyroid cancer. The aim of the current study was to determine the diagnostic utility of an 8-gene assay to distinguish benign ...
Tomei Sara, Marchetti Ivo, Zavaglia Katia, Lessi Francesca, Apollo Alessandro, Aretini Paolo, Di Coscio Giancarlo, Bevilacqua Generoso, Mazzanti Chiara   +8 more
doaj   +1 more source