Results 11 to 20 of about 423,872 (249)

The Matthews correlation coefficient (MCC) should replace the ROC AUC as the standard metric for assessing binary classification

open access: yesBioData Mining, 2023
Binary classification is a common task for which machine learning and computational statistics are used, and the area under the receiver operating characteristic curve (ROC AUC) has become the common standard metric to evaluate binary classifications in ...
Davide Chicco, Giuseppe Jurman
doaj   +1 more source

A Novel Linear Classifier for Class Imbalance Data Arising in Failure-Prone Air Pressure Systems

open access: yesIEEE Access, 2021
An Air Pressure System (APS) is one of the crucial components of an automobile. Its failure leads to financial loses, and it may lead to loss of lives. Thus predicting such failure is a critical problem that requires a rigorous solution.
Mujahid N. Syed   +4 more
doaj   +1 more source

Naringenin alters the pharmacokinetics of ranolazine in part through the inhibition of cytochrome P450 (3A4) and P-glycoprotein

open access: yesFuture Journal of Pharmaceutical Sciences, 2023
Background This study set out to look at how naringenin affected the pharmacokinetics of ranolazine in rats. The pharmacokinetic investigation of ranolazine in rats following oral administration of ranolazine with or without coadministration of ...
Faisal Alotaibi
doaj   +1 more source

Inference about time-dependent prognostic accuracy measures in the presence of competing risks

open access: yesBMC Medical Research Methodology, 2020
Background Evaluating a candidate marker or developing a model for predicting risk of future conditions is one of the major goals in medicine. However, model development and assessment for a time-to-event outcome may be complicated in the presence of ...
Rajib Dey   +2 more
doaj   +1 more source

Application of SHAP on CatBoost classification for identification of variabels characterizing food insecurity occurrences in Aceh Province households

open access: yesJurnal Natural, 2023
Classification is the process of building a model that can distinguish between different classes of data. The model aims to predict the class of testing data based on patterns or relationships learned from training data.
MUHAMMAD SUBIANTO   +4 more
doaj   +1 more source

LRMCMDA: Predicting miRNA-Disease Association by Integrating Low-Rank Matrix Completion With miRNA and Disease Similarity Information

open access: yesIEEE Access, 2020
Identifying disease-related microRNAs (miRNAs) is crucial to understanding the etiology and pathogenesis of many diseases. However, existing computational methods are facing a few dilemmas such as lacking “negative samples” (i.e.
Junlin Xu   +8 more
doaj   +1 more source

Degree-Based Similarity Indexes for Identifying Potential miRNA-Disease Associations

open access: yesIEEE Access, 2020
Identifying disease-associated miRNAs is helpful to explore the pathogenesis of diseases. However, without foreknowledge of the experimentally valid disease-associated miRNAs information, the development of promising and affordable approaches for ...
Yajie Meng   +3 more
doaj   +1 more source

A modified Wald interval for the area under the ROC curve (AUC) in diagnostic case-control studies [PDF]

open access: yesBMC Medical Research Methodology, 2014
The area under the receiver operating characteristic (ROC) curve, referred to as the AUC, is an appropriate measure for describing the overall accuracy of a diagnostic test or a biomarker in early phase trials without having to choose a threshold. There are many approaches for estimating the confidence interval for the AUC.
Kottas, Martina   +2 more
openaire   +3 more sources

UV SPECTROPHOTOMETRIC METHODS FOR THE SIMULTANEOUS DETERMINATION OF AMOXICILLIN AND FLUCLOXACILLIN. [PDF]

open access: yesAl-Azhar Journal of Pharmaceutical Sciences, 2016
Spectrophotometric methods were introduced for the simultaneous determination of Amoxicillin (AMX) and flucloxacillin(FLX) in their pure forms and  capsules pharmaceutical formulations.
Maya Eissa
doaj   +1 more source

Relationship between Vancomycin Area Under the Concentration-Time Curve (AUC) and Nephrotoxicity in Adults [PDF]

open access: yesOpen Forum Infectious Diseases, 2017
Abstract Background While recent data correlate vancomycin’s ratio of the area under the 24 hour time-concentration curve (AUC0−24h) to the pathogen’s minimal inhibitory concentration (MIC) of > 400 mg*hours/L with a favorable clinical outcome, data are sparse to correlate vancomycin AUC0−24h ...
David Allen, Mary Townsend, Richard Drew
openaire   +1 more source

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