Results 11 to 20 of about 4,093 (106)

Antithrombotic Therapy After Intracerebral Hemorrhage: Real‐World Evidence for In‐Hospital Resumption

CNS Neuroscience &Therapeutics, Volume 32, Issue 5, May 2026.
In‐hospital resumption of antithrombotic therapy after acute spontaneous intracerebral hemorrhage was associated with a reduced risk of ischemic events and no excessive bleeding risk. ABSTRACT Background and Purpose Patients with intracerebral hemorrhage (ICH) who require antithrombotic therapy (AT) face competing risks of recurrent bleeding and ...
Shengde Li, Tian Qu, Xiang Zhou, Qi Miao, Jun Ni, Bin Peng   +5 more
wiley   +1 more source

Dissecting the Chemical and Thermal Stabilities of Tetrads in G‐Quadruplexes to Derive a Structure‐Activity Relation for a Thrombin‐Binding DNA G‐Quadruplex Aptamer

ChemBioChem, Volume 27, Issue 8, April 2026.
Extended variants of the G‐quadruplex thrombin binding aptamer exhibit differential anticoagulation activities. We show that 3’ terminal extensions increase nuclease resistance, while variations in thermal stability directly impact activity. Hydrogen exchange nuclear magnetic resonance spectroscopy (NMR) report on thermodynamic properties of the base ...
Julia Wirmer‐Bartoschek, Jan‐Peter Ferner, Alexander Heckel, Harald Schwalbe   +3 more
wiley   +1 more source

Therapeutic Dilemmas in Patients With Antineutrophil Cytoplasmic Antibody–Associated Vasculitis: Diffuse Alveolar Hemorrhage and Venous Thromboembolism

ACR Open Rheumatology, Volume 8, Issue 3, March 2026.
Objective Diffuse alveolar hemorrhage (DAH) is a life‐threatening presentation of antineutrophil cytoplasmic antibody–associated vasculitis (AAV). Patients with AAV are at an increased risk of venous thromboembolic events (VTEs). These manifestations can co‐occur; however, the prognosis and management of these patients are poorly understood. Methods In
Elif D. Ediboglu, Samuel D. Falde, Misbah Baqir, Rodrigo Cartin‐Ceba, Robert McBane, Ulrich Specks   +5 more
wiley   +1 more source

Evaluating the Prevalence of Optimal Neurodevelopmental Outcome at 4.5‐Years in Children Previously on Ventricular Assist Device Support

Pediatric Transplantation, Volume 30, Issue 2, February 2026.
One third of children implanted with a VAD at < 6 years of age will have an optimal neurodevelopmental outcome. Being female and having a VAD implanted after 2015 is associated with an optimal outcome while a neurological insult is associated with a nonoptimal outcome.
Shannon Oliver, Holger Buchholz, Darren H. Freed, De Villiers Jonker, Ari R. Joffe, Mahsa Saeidian, Irina Dinu, Simon Urschel, Tara Pidborochynski, Joseph Atallah, Charlene M. T. Robertson, Jessica Zvonkovic, Jennifer Conway   +12 more
wiley   +1 more source

AIE‐Mediated In Situ Monitoring of Protein Aggregates During Coagulation and Screening of Anticoagulant Agents

Aggregate, Volume 7, Issue 1, January 2026.
The process of screening active monomers via BioSTAS technology. (A) Analyzing the properties and luminescence mechanism of an AIE molecule through density functional theory and MD simulation. (B) The establishment of a screening model, including biosensing and affinity chromatography. (C) Screening and identification of active substances.
Shuxian Zhang, Hui Yuan, Lingling Yang, Xiaoxuan Fan, Keshuai Liu, Rui Mai, Wangyan Zhao, Cheng Liu, Qiang Han, Yongjian Ai, Qionglin Liang, Xueqin Ma, Guoning Chen   +12 more
wiley   +1 more source

Back Again to the Future: A New Era for Cerebroprotection

Annals of Neurology, Volume 99, Issue 1, Page 19-34, January 2026.
Cerebroprotection is a fresh framework for designing neurological therapy that targets glia and vascular cells, in addition to neurons. In the future, successful cerebroprotection will involve targeting all elements of the neurovascular unit. Preclinical trials must include functional outcomes, as well as lesion morphometry.
Patrick Lyden
wiley   +1 more source

Neck‐vein thrombosis during spaceflight

British Journal of Clinical Pharmacology, Volume 92, Issue 1, Page 24-34, January 2026.
Spaceflight imposes unique environmental challenges, including weightlessness, increased radiation exposure and confinement, which can lead to unexpected health effects. One such example is neck‐vein thrombosis, a condition rarely seen on Earth without predisposing factors such as venous catheters or infections.
Ulrich Limper, Jens Jordan
wiley   +1 more source

A Diagnostic Challenge: Post‐Transfusion Purpura Unmasked After Multiple Transfusions

Clinical Case Reports, Volume 14, Issue 1, January 2026.
ABSTRACT Post‐transfusion purpura (PTP) is a rare immune‐mediated post‐transfusion reaction resulting in severe thrombocytopenia. This case presents a 52‐year‐old female with profound thrombocytopenia following multiple transfusions. PTP was not initially suspected due to her history of comorbid anti‐phospholipid antibody syndrome (APS), chemotherapy ...
Jacintha Thomas, Priyal Gopalan, Tanya M. Wildes   +2 more
wiley   +1 more source

Publication Only

HemaSphere, Volume 10, Issue S1, June 2026.
wiley   +1 more source

Impact of non-amyloid cerebral small vessel disease on the efficacy and safety of argatroban in acute ischemic stroke: a retrospective cohort study. [PDF]

Front Neurol
Liu F, Wu Q, Lin Y, Chen J.
europepmc   +1 more source