Results 141 to 150 of about 843,121 (388)

Tunable Synthetic Hydrogel Modulates Hepatic Lineage Specification of Human Liver Organoid

Advanced Functional Materials, EarlyView.
In this study, a synthetic hydrogel is reported that supports the formation of hiPSC‐derived human liver organoids (HLOs). Hepatic lineage specification can be modulated via conjugation of RGD peptide to hydrogel: RGD‐conjugated hydrogels promote cholangiocyte differentiation, whereas RGD‐free hydrogels favor hepatocyte commitment of HLO cells.
Lei Wang, Lasse Riediger, Qi Rao, Xun Xu, Yan Nie, Yiduo Zhou, Junyao Zhang, Peng Tang, Weiwei Wang, Frank Tacke, Adrien Guillot, Ludovic Vallier, Irene Talon, Wenzhong Li, Yi‐An Yang, Rainer Haag, Nan Ma   +16 more
wiley   +1 more source

Nutrición en el paciente con pancreatitis aguda grave: guía de manejo clínico Nutrition in the patient with severe acute pancreatitis: clinical management guideline

Revista Colombiana de Cirugía, 2010
Objetivo: proponer una guía de manejo para la nutrición en los pacientes con pancreatitis aguda grave basada en la mejor evidencia disponible. Diseño: revisión sistemática y guía de práctica clínica.
Norton Pérez, Liliana Echeverri, Miguel Ángel Mejía, Óscar López, Sergio Vega, Camilo Vélez, Miladys Gallego, Constanza Reyes, Jorge Luis Cruz, Orlando Villanueva, José María Duarte   +10 more
doaj  

Pegylated arginine deiminase synergistically increases the cytotoxicity of gemcitabine in human pancreatic cancer. [PDF]

, 2014
BackgroundPancreatic ductal adenocarcinoma has proven to be one of the most chemo-resistant among all solid organ malignancies. Several mechanisms of resistance have been described, though few reports of strategies to overcome this chemo-resistance have ...
Bold, Richard J, Daylami, Rouzbeh, Muilenburg, Diego J, Virudachalam, Subbulakshmi   +3 more
core   +2 more sources

The Hierarchical Structure of Sheep Wool and Its Impact on Physical Properties

Advanced Functional Materials, EarlyView.
Sheep wool, a prevalent α‐keratinous fiber, is an essential model for studying protein‐based fibers. Its genetic diversity across breeds enables the establishment of multiscale structure‐property relationships, uncovering previously elusive insights into wool's hierarchical structure.
Serafina R. France Tribe, Paloma X. Lee, Caterina Czibula, Mónica G. Simões, Reiner Bleher, Keith E. Duncan, Michael Thoman, Christopher N. Topp, Vinayak P. Dravid, Cécile A. C. Chazot   +9 more
wiley   +1 more source

Is there NO treatment for severe sepsis? [PDF]

, 2008
Sepsis is a systemic inflammatory response syndrome in the presence of suspected or proven infection, and it may progress to or encompass organ failure (severe sepsis) and hypotension (septic shock).
Bredan, Amin, Cauwels, Anje
core   +2 more sources

Control of TSC2-Rheb signaling axis by arginine regulates mTORC1 activity

eLife, 2016
The mammalian target of rapamycin complex 1 (mTORC1) is the key signaling hub that regulates cellular protein homeostasis, growth, and proliferation in health and disease.
Bernadette Carroll, D. Maetzel, O. Maddocks, Gisela Otten, M. Ratcliff, Graham R. Smith, E. Dunlop, J. Passos, O. Davies, R. Jaenisch, A. Tee, Sovan Sarkar, V. Korolchuk   +12 more
semanticscholar   +1 more source

Smart, Bio‐Inspired Polymers and Bio‐Based Molecules Modified by Zwitterionic Motifs to Design Next‐Generation Materials for Medical Applications

Advanced Functional Materials, EarlyView.
Bio‐based and (semi‐)synthetic zwitterion‐modified novel materials and fully synthetic next‐generation alternatives show the importance of material design for different biomedical applications. The zwitterionic character affects the physiochemical behavior of the material and deepens the understanding of chemical interaction mechanisms within the ...
Theresa M. Lutz, Jonas De Breuck, Sahar Salehi, Meike N. Leiske   +3 more
wiley   +1 more source

Encapsulation performance of layer-by-layer microcapsules for proteins [PDF]

, 2011
This study reports on the encapsulation efficiency of proteins in dextran sulfate/poly-l-arginine-based microcapsules, fabricated via layer-by-layer assembly (LbL).
De Smedt, Stefaan, De Temmerman, Marie-Luce, De Vos, Filip, Demeester, Jo   +3 more
core   +2 more sources

Arginine Demethylation of G3BP1 Promotes Stress Granule Assembly*

Journal of Biological Chemistry, 2016
Stress granules (SGs) are cytoplasmic condensates of stalled messenger ribonucleoprotein complexes (mRNPs) that form when eukaryotic cells encounter environmental stress.
W. Tsai, Sitaram Gayatri, Lucas C. Reineke, G. Sbardella, M. Bedford, R. Lloyd   +5 more
semanticscholar   +1 more source

Advanced Cellulose‐Based Gels for Wearable Physiological Monitoring: From Fiber Modification to Application Optimization

Advanced Functional Materials, EarlyView.
This review discusses cellulose‐based hydrogels technology, analyzes their application progress in physiological signal monitoring, and explores the effects of pretreatment, crosslinking, and molding methods on gel performance, to provide valuable insights into the efficient utilization of plant fibers and the environmentally friendly development of ...
Zhiming Wang, Jinxuan Jiang, Kexin Wei, Xiaojian Zhou, Muhammad Wakil Shahzad, Yifan Li, Xuehua Zhang, Ben Bin Xu, Shengbo Ge   +8 more
wiley   +1 more source