Results 141 to 150 of about 784,368 (407)

Role of arginine and/or taurine in protection against gentamicin-induced nephrotoxicity in male and female rats

open access: yesJournal of Medicine in Scientific Research, 2019
Background As a highly effective antibiotic, gentamicin is used in the treatment of serious and life-threatening gram-negative infections. L-arginine (2-amino-5-guanidino-pentanoic acid) has a protective role on renal failure that induced by gentamicin ...
Wafaa M Ismaeil, Amal H Emara
doaj   +1 more source

Arginine demethylation is catalysed by a subset of JmjC histone lysine demethylases

open access: yesNature Communications, 2016
While the oxygen-dependent reversal of lysine Nɛ-methylation is well established, the existence of bona fide Nω-methylarginine demethylases (RDMs) is controversial.
L. Walport   +6 more
semanticscholar   +1 more source

Transmembrane Activation of Catalysis and Protein Refolding in Synthetic Cells by Enzymes and Nanozymes

open access: yesAdvanced Functional Materials, EarlyView.
Synthetic cells are engineered herein to respond to an external chemical messenger by the activation of intracellular catalysis. The chemical messenger molecules are catalytically generated by an extracellular enzyme or a mineral surface, whereas the intracellular catalysis emerges via direct enzyme activation or via protein refolding.
Dante G. Andersen   +5 more
wiley   +1 more source

ArgR is an essential local transcriptional regulator of the arcABC-operon in Streptococcus suis and crucial for biological fitness in acidic environment [PDF]

open access: yes, 2011
Streptococcus suis is one of the most important pathogens in pigs and can also cause severe infections in humans. Despite its clinical relevance very little is known about the factors contributing to its virulence.
Benga, L.   +6 more
core   +2 more sources

Nutrition et santé : lipides et protéines d’origine végétale - De nouvelles données pour juger de la qualité des protéines végétales chez l’homme - Implications et perspectives

open access: yesOléagineux, Corps gras, Lipides, 2003
La qualité des protéines pour l’alimentation de l’homme est un sujet très ancien mais les différentes méthodes proposées jusqu’ici pour évaluer la qualité protéique ont été largement critiquées, pour des problèmes conceptuels et méthodologiques.
Mariotti François, Tomé Daniel
doaj   +1 more source

Personalized Metabolic Analysis of Diseases [PDF]

open access: yesarXiv, 2020
The metabolic wiring of patient cells is altered drastically in many diseases, including cancer. Understanding the nature of such changes may pave the way for new therapeutic opportunities, as well as the development of personalized treatment strategies for patients.
arxiv  

Sensitivity of Colorectal Cancer to Arginine Deprivation Therapy is Shaped by Differential Expression of Urea Cycle Enzymes

open access: yesScientific Reports, 2018
Tumors deficient in the urea cycle enzymes argininosuccinate synthase-1 (ASS1) and ornithine transcarbamylase (OTC) are unable to synthesize arginine and can be targeted using arginine-deprivation therapy.
Constantinos Alexandrou   +15 more
semanticscholar   +1 more source

High‐Throughput Microfluidic‐Mediated Assembly of Layer‐By‐Layer Nanoparticles

open access: yesAdvanced Functional Materials, EarlyView.
The layer‐by‐layer (LbL) assembly of polymer films on nanoparticle (NP) surfaces is a promising technique for targeted drug delivery. Despite its success in preclinical mouse models, a current good manufacturing practices (cGMP) compliant, clinical‐scale production method has been lacking.
Ivan S. Pires   +4 more
wiley   +1 more source

Arginine thioacid in synthesis of arginine conjugates and peptides

open access: yesRSC Adv., 2014
Protected arginine thioacid enables convenient N-acylation with no detectable racemization. We report efficient syntheses of potentially biologically active arginine conjugates and novel arginine-containing di-, tri- and tetrapeptides in good yields without loss of chiral integrity.
Ellen Toneff   +7 more
openaire   +2 more sources

3D Bioprinted Head and Neck Squamous Cell Carcinoma (HNSCC) Model Using Tunicate Derived Nanocellulose (NC) Bioink

open access: yesAdvanced Healthcare Materials, Volume 14, Issue 7, March 14, 2025.
A 3D bioprinted HNSCC model for use in anti‐cancer drug testing is established in proof‐of‐concept. The innovative tunicate‐derived nanocellulose hydrogel proved to be a viable alternative to gelatin‐based hydrogel, offering improved bioprintability for HNSCC model establishment.
Alexya Azhakesan   +7 more
wiley   +1 more source

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