Histone arginine methylation [PDF]
FEBS Letters, 2010 Arginine methylation is a common posttranslational modification (PTM). This type of PTM occurs on both nuclear and cytoplasmic proteins, and is particularly abundant on shuttling proteins. In this review, we will focus on one aspect of this PTM: the diverse roles that arginine methylation of the core histone tails play in regulating chromatin function.
Mark T. Bedford, Alessandra Di Lorenzo
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Regulation of arginine transport by GCN2 eIF2 kinase is important for replication of the intracellular parasite Toxoplasma gondii [PDF]
, 2019 Toxoplasma gondii is a prevalent protozoan parasite that can infect any nucleated cell but cannot replicate outside of its host cell. Toxoplasma is auxotrophic for several nutrients including arginine, tryptophan, and purines, which it must acquire from ...
Amin, Parth H. +3 more
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Biomedicine & Pharmacotherapy, 2002 L-Arginine (Arg) is classified as an essential amino acid for birds, carnivores and young mammals and a conditionally essential amino acid for adults. It is converted by arginase to L-ornithine, a precursor of polyamines and urea, which is important in the urea cycle.
H, Tapiero +3 more
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Increased glycation and oxidative damage to apolipoprotein B100 of LDL cholesterol in patients with type 2 diabetes and effect of metformin [PDF]
, 2010 OBJECTIVE The aim of this study was to investigate whether apolipoprotein B100 of LDL suffers increased damage by glycation, oxidation, and nitration in patients with type 2 diabetes, including patients receiving metformin therapy.
A. Ceriello +25 more
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Proteomics profiling of arginine methylation defines PRMT5 substrate specificity
Science Signaling, 2019 Proteomics identifies target sites and substrates of the arginine methyltransferase PRMT5. Profiling PRMT5 The enzyme PRMT5 methylates arginine residues in target proteins to modify their function.
D. Musiani +12 more
semanticscholar +1 more source
Interplay between R513 methylation and S516 phosphorylation of the cardiac voltage-gated sodium channel [PDF]
, 2014 Arginine methylation is a novel post-translational modification within the voltage-gated ion channel superfamily, including the cardiac sodium channel, Naᵥ1.5.
Beltran-Alvarez, Pedro +5 more
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Can Arginine Help to Improve Milk Supply in Humans? It Does in Cows
Proceedings, 2023 Arginine can be metabolized into nitric oxide, polyamine, creatine, or agmatine, and each of those metabolites has several biological functions [...]
Luoyang Ding +7 more
doaj +1 more source
Autophagy maintains tumor growth through circulating arginine
Nature, 2018 Autophagy captures intracellular components and delivers them to lysosomes, where they are degraded and recycled to sustain metabolism and to enable survival during starvation1–5.
Laura Poillet-Perez +16 more
semanticscholar +1 more source
Effects of Arginine and Arginine Mimics on Antimicrobial Peptide Behavior [PDF]
Biophysical Journal, 2013 Antimicrobial peptides are naturally occurring components of the innate immune system which serve as a first line of defense against bacterial infection. While hundreds of antimicrobial peptides have been identified from natural sources, there is little in the way of consensus sequences that can identify peptides as antimicrobial.
Angela L. Picciano +2 more
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Tailored second line therapy in asthmatic children with the arginine-16 genotype [PDF]
, 2012 The arginine-16 beta-2 receptor genotype confers increased susceptibility to exacerbations in asthmatic children taking regular long acting beta-2 agonists.
Aziz +27 more
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