Results 61 to 70 of about 784,368 (407)
Is Arginine Charged in a Membrane? [PDF]
"Charged" amino acids play countless important roles in protein structure and function. Yet when these side chains come into contact with membranes we do not fully understand their behavior. This is highlighted by a recent model of voltage-gated ion channel activity and translocon-based experiments that suggest small penalties to expose these side ...
Toby W. Allen+3 more
openaire +2 more sources
To Be or Not To Be a Molecular Ion: The Role of the Solvent in Photoionization of Arginine. [PDF]
Application of photoionization mass spectroscopy, a technique capable of assessing protonation states in complex molecules in the gas phase, is challenging for arginine due to its fragility. We report photoionization efficiencies in the valence region of
Ahmed, Musahid+7 more
core +2 more sources
ADP-ribosylation of arginine [PDF]
Arginine adenosine-5'-diphosphoribosylation (ADP-ribosylation) is an enzyme-catalyzed, potentially reversible posttranslational modification, in which the ADP-ribose moiety is transferred from NAD(+) to the guanidino moiety of arginine. At 540 Da, ADP-ribose has the size of approximately five amino acid residues.
Friedrich Haag+3 more
openaire +3 more sources
Non-Histone Arginine Methylation by Protein Arginine Methyltransferases [PDF]
Protein arginine methyltransferase (PRMT) enzymes play a crucial role in RNA splicing, DNA damage repair, cell signaling, and differentiation. Arginine methylation is a prominent posttransitional modification of histones and various non-histone proteins that can either activate or repress gene expression.
Ayad A. Al-Hamashi+2 more
openaire +2 more sources
A novel bacterial l-arginine sensor controlling c-di-GMP levels in Pseudomonas aeruginosa [PDF]
Nutrients such as amino acids play key roles in shaping the metabolism of microorganisms in natural environments and in host–pathogen interactions.
Cutruzzolà, F.+8 more
core +1 more source
The prevalence of dentin hypersensitivity in Taiwan has been reported up to 38%. The aim of this study was to evaluate the clinical efficacy of desensitizing toothpaste containing 8.0% arginine and calcium carbonate in treating dentin hypersensitivity ...
Hui-Chieh Hsu+2 more
doaj +1 more source
Regulation of arginine transport by GCN2 eIF2 kinase is important for replication of the intracellular parasite Toxoplasma gondii [PDF]
Toxoplasma gondii is a prevalent protozoan parasite that can infect any nucleated cell but cannot replicate outside of its host cell. Toxoplasma is auxotrophic for several nutrients including arginine, tryptophan, and purines, which it must acquire from ...
Amin, Parth H.+3 more
core +1 more source
Entropic stabilization of proteins and its proteomic consequences [PDF]
We report here a new entropic mechanism of protein thermostability due to residual dynamics of rotamer isomerization in native state. All-atom simulations show that Lysines have much greater number of accessible rotamers than Arginines in folded states of proteins.
arxiv +1 more source
Electron Attachment to DNA: The Protective Role of Amino Acids [PDF]
We have studied the effect of amino acids on electron attachment properties of DNA nucleobases, taking cytosine as a model system. The equation of motion coupled cluster theory with an extended basis set has been used to simulate the electron-attached state of the DNA model system. Four selected amino acids, Arginine, Alanine, Lysine, and Glycine which
arxiv +1 more source
Histone arginine methylation [PDF]
Arginine methylation is a common posttranslational modification (PTM). This type of PTM occurs on both nuclear and cytoplasmic proteins, and is particularly abundant on shuttling proteins. In this review, we will focus on one aspect of this PTM: the diverse roles that arginine methylation of the core histone tails play in regulating chromatin function.
Mark T. Bedford, Alessandra Di Lorenzo
openaire +3 more sources