Results 81 to 90 of about 39,159 (231)

Nephrogenic diabetes insipidus (NDI): clinical, laboratory and genetic characterization of five Brazilian patients

Clinics, 2009
INTRODUCTION: Nephrogenic diabetes insipidus is characterized by a lack of response in the distal nephron to the antidiuretic hormone arginine vasopressin.
Maria Helena Vaisbich, Juliana Carneiro, Wolfanga Bóson, Bruna Resende, Luiz De Marco, Rachel S Honjo, Chong Ae Kim, Vera H Koch   +7 more
doaj   +1 more source

Erg currents support electrical bursting in murine anterior pituitary corticotrophs

The Journal of Physiology, EarlyView.
Abstract figure legend Anterior pituitary corticotrophs are a central component of the hypothalamic‐pituitary‐adrenal (HPA) axis that controls the release of glucocorticoids from the adrenal gland in response to stress. The hypothalamic secretagogue corticotrophin releasing hormone (CRH) promotes electrical bursting of mouse anterior pituitary ...
Sooraj V. Nair, Nicola Romanò, Peter J. Duncan, Paul Le Tissier, Richard Bertram, Michael J. Shipston   +5 more
wiley   +1 more source

Multiphase management of sodium imbalance following traumatic brain injury: a case-based review

BMC Pediatrics
Background This review article discusses a case of sodium imbalance and fluid dysregulation in a patient with traumatic brain injury (TBI), progressing through phases including mannitol-induced osmotic diuresis, arginine vasopressin deficiency (central ...
Vinson James, Laura Nimkoff
doaj   +1 more source

Aspartame Increases the Risk of Pancreatic Ductal Adenocarcinoma

eFood, Volume 7, Issue 3, June 2026.
Aspartame (APM) is a widely used artificial sweetener associated with various health concerns, including potential links to diabetes, cardiovascular diseases, and an increased risk of cancer. A comprehensive approach incorporating data mining, machine learning, network toxicology, molecular docking, molecular dynamics simulations, and clinical sample ...
Jumin Xie, Wei Fang, Zean Song, Zhang Yu, Ying Zhu, Shaoping Liu   +5 more
wiley   +1 more source

Intravenous Tolvaptan Sodium Phosphate Can Fail to Improve Fluid Overload Due to Heart Failure in Patients With Chronic Kidney Disease: A Case Report

Pharmacology Research &Perspectives, Volume 14, Issue 3, June 2026.
ABSTRACT Tolvaptan is widely used as an adjunct oral diuretic to loop and thiazide diuretics for the management of fluid overload in patients with congestive heart failure. Recently, tolvaptan sodium phosphate (TSP), a water‐soluble prodrug of tolvaptan, was developed for intravenous administration and has demonstrated efficacy and safety in clinical ...
Takaya Uno, Ichiro Nakakura, Akari Ikeda, Atsuki Hosoda, Yutaro Mukai, Kaori Yamanishi, Naohiro Ohara, Kaori Imanishi, Yoshiko Une, Satoshi Yokoyama, Kouichi Hosomi   +10 more
wiley   +1 more source

Morphofunctional Alterations of the Hypothalamus and Social Behavior in Autism Spectrum Disorders

Brain Sciences, 2020
An accumulating body of evidence indicates a tight relationship between the endocrine system and abnormal social behavior. Two evolutionarily conserved hypothalamic peptides, oxytocin and arginine-vasopressin, because of their extensively documented ...
Andrea Caria, Luciana Ciringione, Simona de Falco   +2 more
doaj   +1 more source

GRKs and arrestins: Nomenclature and functions in GPCR‐dependent and ‐independent signalling

British Journal of Pharmacology, Volume 183, Issue 11, Page 2619-2633, June 2026.
G protein‐coupled receptor (GPCR) kinases (GRKs) and arrestins play a critical role in the regulation of GPCR signalling. Historic names of mammalian GRKs were replaced by systematic ones in the 1990s; however, both kinds of names are currently in use for mammalian arrestins.
Vsevolod V. Gurevich
wiley   +1 more source

Intravenous Oxytocin Has no Effect on Ad Libitum Food Intake or Postprandial Plasma Glucose Concentrations in Individuals With Obesity: A Randomised, Placebo‐Controlled, Double‐Blind, Crossover Study

Diabetes, Obesity and Metabolism, Volume 28, Issue 6, Page 4671-4682, June 2026.
ABSTRACT Introduction Oxytocin is expressed throughout the small intestine, suggesting a role for oxytocin in postprandial metabolism. Accordingly, single‐dose intranasal oxytocin reduces food intake and improves glucose tolerance. We investigated the effects of a continuous intravenous oxytocin infusion on ad libitum food intake, appetite sensations ...
Ida M. Gether, Vivian Kliim‐Hansen, Petur T. Olafsson, Miriam G. Pedersen, Casper K. Nielsen, Anne‐Marie Ellegaard, Mikkel B. Christensen, Jens F. Rehfeld, Jørn W. Helge, Jens J. Holst, Bolette Hartmann, Filip K. Knop, Lærke S. Gasbjerg, Asger B. Lund   +13 more
wiley   +1 more source

Effect of vasopressin 1b receptor blockade on the hypothalamic-pituitary-adrenal response of chronically stressed rats to a heterotypic stressor [PDF]

, 2009
Exposure to chronic restraint (CR) modifies the hypothalamic–pituitary–adrenal (HPA) axis response to subsequent acute stressors with adaptation of the response to a homotypic and sensitization of the response to a heterotypic stressor. Since vasopressin
Craighead, Mark, Harrison, Louise R., Lightman, Stafford L., MacSweeney, Cliona P., Spiga, Francesca, Thomson, Fiona J.   +5 more
core   +1 more source

Renal pericytes: regulators of medullary blood flow [PDF]

, 2012
Regulation of medullary blood flow (MBF) is essential in maintaining normal kidney function. Blood flow to the medulla is supplied by the descending vasa recta (DVR), which arise from the efferent arterioles of juxtamedullary glomeruli.
Agmon Y., Beach R.E., Biondi M., Burnstock G., Casellas D., Cohen H.J., Edwards R.M., Guan Z., Harrison‐Bernard L.M., Harrison‐Bernard L.M., Jamison R.L., Kreisberg M.S., Kriz W., Larson T.S., Lazarowski E.R., Lerman L.O., Majid D.S., Pallone T.L., Rouget C., Seldin D.W., Stern M.D., Strick D.M., Takenaka T., Takezawa K., Turner M.R., Unwin R.J., Yamagishi S., Yang S.   +27 more
core   +1 more source