Results 31 to 40 of about 27,759 (158)

Enzymes Involved in the Biosynthesis of Arginine from Ornithine in Maritime Pine (Pinus pinaster Ait.)

Plants, 2020
The amino acids arginine and ornithine are the precursors of a wide range of nitrogenous compounds in all living organisms. The metabolic conversion of ornithine into arginine is catalyzed by the sequential activities of the enzymes ornithine ...
José Alberto Urbano-Gámez, Jorge El-Azaz, Concepción Ávila, Fernando N. de la Torre, Francisco M. Cánovas   +4 more
doaj   +1 more source

Urea cycle disorders in Argentine patients: clinical presentation, biochemical and genetic findings

Orphanet Journal of Rare Diseases, 2019
Background The incidence, prevalence, and molecular epidemiology of urea cycle disorders (UCDs) in Argentina remain underexplored. The present study is the first to thoroughly assess the clinical and molecular profiles of UCD patients examined at a ...
Silene M. Silvera-Ruiz, José A. Arranz, Johannes Häberle, Celia J. Angaroni, Miriam Bezard, Norberto Guelbert, Adriana Becerra, Fernanda Peralta, Raquel Dodelson de Kremer, Laura E. Laróvere   +9 more
doaj   +1 more source

Effects of Thermal Conditioning on Changes in Hepatic and Muscular Tissue Associated With Reduced Heat Production and Body Temperature in Young Chickens

Frontiers in Veterinary Science, 2021
Effects of increased summer temperatures on poultry production are becoming more pronounced due to global warming, so it is important to consider approaches that might reduce heat stress in chickens.
Yoshimitsu Ouchi, Vishwajit S. Chowdhury, John F. Cockrem, Takashi Bungo   +3 more
doaj   +1 more source

Cerebral H-1 MR spectroscopy showing elevation of brain guanidino acetate in argininosuccinate lyase deficiency

, 2006
MR spectroscopy in a patient with argininosuccinate lyase deficiency revealed elevated cerebral guanidinoacetate signals, indicating that the phenomenon of increased levels of this compound in brain tissue is not limited to creatine deficiencies.
van Spronsen, FJ, Reijngoud, DJ; id_orcid, Soorani-Lunsing, RJ, Oudkerk, M, Oudkerk, M; id_orcid, Sijens, PE, Reijngoud, DJ   +6 more
core   +1 more source

Reconstitution of T Cell Proliferation under Arginine Limitation: Activated Human T Cells Take Up Citrulline via L-Type Amino Acid Transporter 1 and Use It to Regenerate Arginine after Induction of Argininosuccinate Synthase Expression

Frontiers in Immunology, 2017
In the tumor microenvironment, arginine is metabolized by arginase-expressing myeloid cells. This arginine depletion profoundly inhibits T cell functions and is crucially involved in tumor-induced immunosuppression.
Anke Werner, Anke Werner, Miriam Koschke, Nadine Leuchtner, Claudia Luckner-Minden, Alice Habermeier, Johanna Rupp, Christin Heinrich, Roland Conradi, Ellen I. Closs, Markus Munder, Markus Munder   +11 more
doaj   +1 more source

Aberrant expression and distribution of enzymes of the urea cycle and other ammonia metabolizing pathways in dogs with congenital portosystemic shunts. [PDF]

PLoS ONE, 2014
The detoxification of ammonia occurs mainly through conversion of ammonia to urea in the liver via the urea cycle and glutamine synthesis. Congenital portosystemic shunts (CPSS) in dogs cause hyperammonemia eventually leading to hepatic encephalopathy ...
Giora van Straten, Frank G van Steenbeek, Guy C M Grinwis, Robert P Favier, Anne Kummeling, Ingrid H van Gils, Hille Fieten, Marian J A Groot Koerkamp, Frank C P Holstege, Jan Rothuizen, Bart Spee   +10 more
doaj   +1 more source

Inhibition of argininosuccinate synthase (ASS) affected ammonia excretion in yellow catfish Pelteobagrus fulvidraco during acute ammonia poisoning

Aquaculture Reports, 2022
Ammonia is toxic to most fish. Different fish have different treatment methods for ammonia toxicity, mainly including urea cycle and glutamine synthesis pathway, depending on their physiological status.
Pengwei Song, Ming Li, Muzi Zhang, Haibo Jiang, Jian Shao, Rixin Wang, Yunxia Qian, Dexiang Feng   +7 more
doaj   +1 more source

Species Dynamics and Gene Expression in Algal Polycultures Under Mixotrophic Cultivation in Outdoor Pilot‐Scale Nordic Conditions

Biotechnology and Bioengineering, EarlyView.
These results demonstrate that mixotrophic conditions drive both microbial community shifts and metabolic reprogramming, underscoring the importance of cultivation strategy and polyculture selection for targeted applications such as nutrient recovery and bioproduct generation.
Quyen Nham, Hanna Farnelid, Catherine Legrand, Elin Lindehoff   +3 more
wiley   +1 more source

Unmet Needs of Parents of Children with Urea Cycle Disorders

Children, 2022
(1) Background: Phenotypic diversity and long-term health outcomes of individuals with urea cycle disorders (UCDs) have been described in detail. However, there is limited information on the burden on affected families.
Mara Scharping, Heiko Brennenstuhl, Sven F. Garbade, Beate Wild, Roland Posset, Matthias Zielonka, Stefan Kölker, Markus W. Haun, Thomas Opladen   +8 more
doaj   +1 more source

Inherited metabolic epilepsies–established diseases, new approaches

Epilepsia Open, EarlyView.
Abstract Inherited metabolic epilepsies (IMEs) represent the inherited metabolic disorders (IMDs) in which epilepsy is a prevailing component, often determining other neurodevelopmental outcomes associated with the disorder. The different metabolic pathways affected by individual IMEs are the basis of their rarity and heterogeneity.
Itay Tokatly Latzer, Phillip L. Pearl
wiley   +1 more source