Results 91 to 100 of about 1,331,962 (291)
The Efficient Evaluation of the Hypergeometric Function of a Matrix Argument
, 2005 We present new algorithms that efficiently approximate the hypergeometric function of a matrix argument through its expansion as a series of Jack functions.
Edelman, Alan, Koev, Plamen
core +2 more sources
FEBS Letters, EarlyView.This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva +5 more
wiley +1 more source
In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS
FEBS Letters, EarlyView.We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka +11 more
wiley +1 more source
Team-based learning (TBL): An Argument for Faculty's Evaluation
INNOVATIONS in Pharmacy, 2014 Team-based learning (TBL) is increasingly used for presenting educational information to students in colleges of pharmacy. Several studies have shown a positive impact on students both in terms of academic performance and comprehension.
Clark D. Kebodeaux +2 more
doaj +1 more source
Judgment Aggregation in Multi-Agent Argumentation
, 2015 Given a set of conflicting arguments, there can exist multiple plausible opinions about which arguments should be accepted, rejected, or deemed undecided. We study the problem of how multiple such judgments can be aggregated.
Awad, Edmond +3 more
core +1 more source
Sequence determinants of RNA G‐quadruplex unfolding by Arg‐rich regions
FEBS Letters, EarlyView.We show that Arg‐rich peptides selectively unfold RNA G‐quadruplexes, but not RNA stem‐loops or DNA/RNA duplexes. This length‐dependent activity is inhibited by acidic residues and is conserved among SR and SR‐related proteins (SRSF1, SRSF3, SRSF9, U1‐70K, and U2AF1).
Naiduwadura Ivon Upekala De Silva +10 more
wiley +1 more source
The Structure and Evaluation of Planning Arguments
Informal Logic, 2010 Arguments commonly used in discussions about design, planning, policy-making issues have not been adequately analyzed in the literature. The structure of such ‘planning arguments’ is discussed.
Thorbjoern Mann
doaj +1 more source
FEBS Letters, EarlyView.The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li +2 more
wiley +1 more source
PICALM::MLLT10 translocated leukemia
FEBS Letters, EarlyView.This comprehensive review of PICALM::MLLT10 translocated acute leukemia provides an in‐depth review of the structure and function of CALM, AF10, and the fusion oncoprotein (1). The multifaceted molecular mechanisms of oncogenesis, including nucleocytoplasmic shuttling (2), epigenetic modifications (3), and disruption of endocytosis (4), are then ...
John M. Cullen +7 more
wiley +1 more source
Informal Logic: This paper addresses the prob-lem of how to identify and evaluate argu-ments made in a nonverbal form. Such arguments may employ images, sounds, or a combination of these in a truly mul-timodal presentation.
Martin Hinton, Gabrijela Kišiček
doaj