Results 191 to 200 of about 16,600,438 (304)

Mechanistic read-across comes of age: a comparative appraisal of EFSA 2025 guidance, ECHA's RAAF, and good read-across practice. [PDF]

Front Toxicol
Hartung T, Rovida C.
europepmc   +1 more source

Survivin and Aurora Kinase A control cell fate decisions during mitosis

Molecular Oncology, EarlyView.
Aurora A interacts with survivin during mitosis and regulates its centromeric role. Loss of Aurora A activity mislocalises survivin, the CPC and BubR1, leading to disruption of the spindle checkpoint and triggering premature mitotic exit, which we refer to as ‘mitotic slippage’.
Hana Abdelkabir, Shalitha Wickrama Arachchige, Sally P. Wheatley   +2 more
wiley   +1 more source

A philosophical defence of limited foreknowledge open theism. [PDF]

Int J Philos Relig
Ackermann M.
europepmc   +1 more source

Reduced vascular leakage correlates with breast carcinoma T regulatory cell infiltration but not with metastatic propensity

Molecular Oncology, EarlyView.
A mouse model for vascular normalization and a human breast cancer cohort were studied to understand the relationship between vascular leakage and tumor immune suppression. For this, endothelial and immune cell RNAseq, staining for vascular function, and immune cell profiling were employed.
Liqun He, Chiara Testini, Neda Hekmati, Altea Bonello, Aglaia Schiza, Emmanuel Nwadozi, Mia Phillipson, Carina Strell, Michael Welsh   +8 more
wiley   +1 more source

Model Answer: An Evaluation of a Complex Argument

Informal Logic, 2004
Mark Letteri
doaj   +1 more source

Comment on: Videographic and microbiologic evaluation of eye drop bottle contamination in clinics: pilot study. [PDF]

J Cataract Refract Surg
Tan JM, Manda SI, Gill MK, Palmer DJ, Lema GMC.   +4 more
europepmc   +1 more source

Liquid biopsy epigenetics: establishing a molecular profile based on cell‐free DNA

Molecular Oncology, EarlyView.
Cell‐free DNA (cfDNA) fragments in plasma from cancer patients carry epigenetic signatures reflecting their cells of origin. These epigenetic features include DNA methylation, nucleosome modifications, and variations in fragmentation. This review describes the biological properties of each feature and explores optimal strategies for harnessing cfDNA ...
Christoffer Trier Maansson, Anders Lade Nielsen, Boe Sandahl Sorensen   +2 more
wiley   +1 more source

Gender, equity, and resilient primary health care in Latin America and the Caribbean: aligned and synergistic goals. [PDF]

Lancet Reg Health Am
Essue BM, Dusing GJ, Anyosa RC.
europepmc   +1 more source

Improving PARP inhibitor efficacy in bladder cancer without genetic BRCAness by combination with PLX51107

Molecular Oncology, EarlyView.
Clinical trials on PARP inhibitors in urothelial carcinoma (UC) showed limited efficacy and a lack of predictive biomarkers. We propose SLFN5, SLFN11, and OAS1 as UC‐specific response predictors. We suggest Talazoparib as the better PARP inhibitor for UC than Olaparib.
Jutta Schmitz, Anna L. Bartkowiak, Michael Rose, Nora Kolks, Patrick Petzsch, Vandana Solanki, Anne Stoffel, Bianca Faßbender, Leandra Lepping, Julka Volkamer, Karl Köhrer, Marc Seifert, Tokameh Mahmoudi, Tahlita C. M. Zuiverloon, Günter Niegisch, Michèle J. Hoffmann   +15 more
wiley   +1 more source

Development of a pain management competency assessment for physiotherapy students: Integrating simulation and written assessments. [PDF]

Can J Pain
Augeard N, Miller J, Bostick G, St-Onge C, Tousignant-Laflamme Y, Hudon A, Walton D, Singer L, Cooper L, Bussières A, Thomas A, Perreault K, Tupper S, Carlesso LC, Stilwell P, Amari F, Varette K, Ashton-James C, Wideman TH.   +18 more
europepmc   +1 more source