Results 241 to 250 of about 16,600,438 (304)

Dammarenediol II enhances etoposide‐induced apoptosis by targeting O‐GlcNAc transferase and Akt/GSK3β/mTOR signaling in liver cancer

open access: yesMolecular Oncology, EarlyView.
Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee   +8 more
wiley   +1 more source

ToxPoint: The case for Equilibrative Nucleoside Transporters in current regulatory guidance. [PDF]

open access: yesToxicol Sci
Martinez-Guerrero L   +4 more
europepmc   +1 more source

On Argument Evaluation

Argumentation and Advocacy, 1985
The traditional assumption that one primary function of argument criticism is to improve decision-making recently has come under attack.
R. C. Rowland
openaire   +2 more sources

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