Results 71 to 80 of about 1,331,962 (291)

Evaluation as institution: a contractarian argument for needs-based economic evaluation

open access: yesBMC Medical Ethics, 2018
Background There is a gap between health economic evaluation methods and the value judgments of coverage decision makers, at least in Germany. Measuring preference satisfaction has been claimed to be inappropriate for allocating health care resources, e ...
Wolf H. Rogowski
doaj   +1 more source

Thou Shalt Not Squander Life – Comparing Five Approaches to Argument Strength

open access: yesStudies in Logic, Grammar and Rhetoric, 2023
Different approaches analyze the strength of a natural language argument in different ways. This paper contrasts the dialectical, structural, probabilistic (or Bayesian), computational, and empirical approaches by exemplarily applying them to a single ...
Zenker Frank   +4 more
doaj   +1 more source

A Carneades reconstruction of Popov v Hayashi [PDF]

open access: yes, 2012
Carneades is an open source argument mapping application and a programming library for building argumentation support tools. In this paper, Carneades’ support for argument reconstruction, evaluation and visualization is illustrated by modeling most of ...
Gordon, Thomas F., Walton, Douglas
core   +3 more sources

Biallelic Inactivation of NSD1 Associated With Carcinogenesis in Sotos Syndrome

open access: yes
Pediatric Blood &Cancer, EarlyView.
Nicholas A. Borja   +8 more
wiley   +1 more source

Upacicalcet: A Novel Intravenous Calcimimetic Agent for Patients Undergoing Hemodialysis With Secondary Hyperparathyroidism

open access: yesTherapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Secondary hyperparathyroidism (SHPT) is a common complication in patients receiving maintenance dialysis, driven by calcium and phosphate metabolism disturbances. Calcimimetics are central to the management of SHPT by enhancing calcium‐sensing receptor sensitivity and reducing parathyroid hormone secretion.
Fumihiko Koiwa   +3 more
wiley   +1 more source

Adjunctive Therapeutic Plasma Exchange in Refractory Adult‐Onset Still's Disease Complicated by Secondary Macrophage Activation Syndrome: A Single‐Center Experience

open access: yesTherapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Introduction Adult‐onset Still's disease (AOSD) complicated by macrophage activation syndrome (MAS) carries substantial mortality. The role of therapeutic plasma exchange (TPE) remains uncertain. Methods We retrospectively analyzed patients with AOSD‐MAS treated with TPE at a single‐center.
Masataka Ueda   +15 more
wiley   +1 more source

Deep Holes in Reed-Solomon Codes Based on Dickson Polynomials

open access: yes, 2016
For an $[n,k]$ Reed-Solomon code $\mathcal{C}$, it can be shown that any received word $r$ lies a distance at most $n-k$ from $\mathcal{C}$, denoted $d(r,\mathcal{C})\leq n-k$. Any word $r$ meeting the equality is called a deep hole. Guruswami and Vardy (
Keti, Matt, Wan, Daqing
core   +1 more source

Organoids in pediatric cancer research

open access: yesFEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

The Athenian against Atheists: Theological Persuasion in Plato’s Laws

open access: yesLiteratūra (Vilnius), 2020
This paper examines the argument for the existence of gods, formulated by the Athenian in the 10th book of Plato’s Laws. The purpose of this investigation is to find out whether the argument persuades its intended audience – the atheists. The analysis is
Simonas Baliukonis
doaj   +1 more source

Reciprocal control of viral infection and phosphoinositide dynamics

open access: yesFEBS Letters, EarlyView.
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley   +1 more source

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