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Arginine methylation as a regulatory ratchet in cancer: From substrate selection to malignant‐state stabilization

Molecular Oncology, EarlyView.
Arginine methylation can be viewed as a persistence‐prone post‐translational modification regulated by a network of PRMTs. Competitive and compensatory interactions among PRMTs can redistribute methylation across substrate pools shaped by sequence, structural, spatial, and environmental layers, reinforcing RNA‐processing, chromatin, and signaling ...
So Hyun Kwon, Ji Min Lee
wiley +1 more source

Letter to the Editor: Less can be more, rethinking colonic biopsy strategies for microscopic colitis in the era of green endoscopy. [PDF]

World J Gastrointest Pharmacol Ther
Agrawal H, Gupta N.
europepmc +1 more source

Mechanisms and therapeutic opportunities of the ribotoxic stress response in cancer

Molecular Oncology, EarlyView.
Cancer cells' high translational demand creates opportunities to therapeutically target ribosome function. Ribosome stalling and collisions activate ZAKα and the ribotoxic stress response (RSR), which can trigger rapid, p53‐independent apoptosis in cancer.
Anastassiya Kim +7 more
wiley +1 more source

Ethical Opinions in Research Ethics Committees: A Narrative Review of Normative Foundations, Deliberative Architecture, and Quality Standards. [PDF]

J Empir Res Hum Res Ethics
Carreira HMRO.
europepmc +1 more source

Navigating the Psychosocial Journey: A Meta-Ethnographic Review of the Psychosocial Needs and Experiences of Children and Adolescents (0-19 Years) Diagnosed With Cancer Across the Care Continuum. [PDF]