Results 71 to 80 of about 19,843 (253)
FEBS Letters, EarlyView.In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai +9 more
wiley +1 more source
Abductive, presumptive and plausible arguments
Informal Logic, 2001 Current practice in logic increasingly accords recognition to abductive, presumptive or plausible arguments, in addition to deductive and inductive arguments. But there is uncertainty about what these terms exactly mean, what the differences between them
Douglas Walton
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Tau acetylation at K331 has limited impact on tau pathology in vivo
FEBS Letters, EarlyView.We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto +3 more
wiley +1 more source
Some Clarifications about the Argumentative Theory of Reasoning. A Reply to Santibáñez Yañez (2012).
Informal Logic, 2012 In “Mercier and Sperber’s Argumentative Theory of Reasoning: From Psychology of Reasoning to Argumentation Studies” (2012) Santibáñez Yañez offers constructive comments and criticisms of the argumentative theory of reasoning. The purpose of this reply is
Hugo Mercier
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APROXIMACIÓN AL ANÁLISIS DE LA VALORACIÓN DE LA PRUEBA USANDO MODIFIED WIGMOREAN ANALYSIS (MWA)
Ius et Praxis, 2009 El presente trabajo muestra cómo el análisis de la valoración de la prueba, usando herramientas de diagramación argumental, puede ayudar a los operadores jurídicos a evaluar la calidad de la argumentación del razonamiento jurídico.
Carlos del Valle Rojas +1 more
doaj
Persuasive Definitions: Values, Meanings and Implicit Disagreements
Informal Logic, 2008 The purpose of this paper is to inquire into the relationship between persuasive definition and common knowledge (propositions generally accepted and not subject to dispute in a discussion).
Fabrizio Macagno, Douglas Walton
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Calpain small subunit homodimerization is robust and calcium‐independent
FEBS Letters, EarlyView.Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy +4 more
wiley +1 more source
Preferential schemes: a reappraisal
PSL Quarterly Review, 2014 The present paper elaborates further on a previous work by the author in which attention was directed to the lack of progress in the flow of resources to developing countries in the 1960s and the urgent need for a significant increase.
N.T. WANG
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Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
FEBS Letters, EarlyView.A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
On the Very Idea of the Very Idea of a Conceptual Scheme
Journal for the History of Analytical PhilosophyIs relativism a coherent thesis? Donald Davidson’s classic ‘On the Very Idea of a Conceptual Scheme’, gives a negative answer. Davidson sought to undermine the coherence of the thesis of relativism, which he takes to be the thesis that different or ...
Gurpreet Rattan
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