Results 101 to 110 of about 1,375,983 (370)

A subset of MMR‐proficient colon cancers responds to neoadjuvant immunotherapy

open access: yesMolecular Oncology, EarlyView.
Tan et al. reveal that a distinct subset of early‐stage pMMR colon cancers can respond to neoadjuvant immunotherapy. In the NICHE‐2 trial, responders (26%) were characterized by chromosomal instability, TP53 mutations, and proliferative cell‐cycle programs, whereas nonresponders showed metabolic and stromal reprogramming with TGF‐β‐driven ...
Eleonora Piumatti   +3 more
wiley   +1 more source

Civil Procedure as a Critical Discussion [PDF]

open access: yes, 2020
This Article develops a model for analyzing legal dispute resolution systems as systems for argumentation. Our model meshes two theories of argument conceived centuries apart: contemporary argumentation theory and classical stasis theory. In this Article,
Larson, Brian N., Provenzano, Susan E.
core   +2 more sources

On Computing Explanations in Argumentation

open access: yesAAAI Conference on Artificial Intelligence, 2015
Argumentation can be viewed as a process of generating explanations. However, existing argumentation semantics are developed for identifying acceptable arguments within a set, rather than giving concrete justifications for them.
Xiuyi Fan, Francesca Toni
semanticscholar   +1 more source

Developing evidence‐based, cost‐effective P4 cancer medicine for driving innovation in prevention, therapeutics, patient care and reducing healthcare inequalities

open access: yesMolecular Oncology, EarlyView.
The cancer problem is increasing globally with projections up to the year 2050 showing unfavourable outcomes in terms of incidence and cancer‐related deaths. The main challenges are prevention, improved therapeutics resulting in increased cure rates and enhanced health‐related quality of life.
Ulrik Ringborg   +43 more
wiley   +1 more source

Skills that Pre-service Primary Teachers’ consider important in argumentation approach [PDF]

open access: yes, 2017
Argumentation as a form of scientific discourse is a powerful tool that allows students questioning, justifying, and evaluating their and others’ claims. In science education, transmissive teaching predominates and this leads to difficulties in students’
Acebal, Maria del Carmen   +2 more
core  

Crowdsourcing Argumentation Structures in Chinese Hotel Reviews

open access: yes, 2017
Argumentation mining aims at automatically extracting the premises-claim discourse structures in natural language texts. There is a great demand for argumentation corpora for customer reviews. However, due to the controversial nature of the argumentation
Gao, Yang   +4 more
core   +1 more source

Redox regulation meets metabolism: targeting PRDX2 to prevent hepatocellular carcinoma

open access: yesMolecular Oncology, EarlyView.
PRDX2 acts as a central redox hub linking metabolic dysfunction‐associated steatohepatitis (MASH) to hepatocellular carcinoma (HCC). In normal hepatocytes, PRDX2 maintains redox balance and metabolic homeostasis under oxidative stress. In contrast, during malignant transformation, PRDX2 promotes oncogenic signaling, stemness, and tumor initiation ...
Naroa Goikoetxea‐Usandizaga   +2 more
wiley   +1 more source

Argument Schemes from the Point of View of Hamblin’s Dialectic

open access: yesInformal Logic, 2011
This paper aims at a normative account of non-deductive argumentation schemes in the spirit of Hamblin’s dialectical philosophy. First, three principles are presented that characterize Hamblin’s dialectical stance.
Jan A. van Laar
doaj   +1 more source

Pushing the bounds of rationality: Argumentation and extended cognition [PDF]

open access: yes, 2016
One of the central tasks of a theory of argumentation is to supply a theory of appraisal: a set of standards and norms according to which argumentation, and the reasoning involved in it, is properly evaluated.
Godden, David
core  

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