Results 81 to 90 of about 117,409 (298)

Unique circulating miRNAome signatures captured with distinct molecular states in Lynch syndrome and sporadic colorectal cancer

open access: yesMolecular Oncology, EarlyView.
Circulating microRNA profiles distinguish nonmalignant Lynch syndrome from cancer‐associated Lynch syndrome, sporadic colorectal cancer, and healthy controls. Age‐stratified analysis reveals disease‐specific regulatory states, and a six‐miRNA panel shows concordant separation in an independent colorectal tissue cohort.
Ramadhani Salum Chambuso   +5 more
wiley   +1 more source

Managing Social Influences through Argumentation-Based Negotiation

open access: yes, 2006
Social influences play an important part in the actions that an individual agent may perform within a multi-agent society. However, the incomplete knowledge and the diverse and conflicting influences present within such societies, may stop an agent from ...
Karunatillake, N. C.   +3 more
core   +1 more source

Argumentación: Hacia Un Esquema Conceptual

open access: yesLogos: Revista de Lingüística, Literatura y Filosofía, 2012
RESUMEN Estudio de la argumentación desde la conceptualización, las estructuras argumentativas, la tipología argumental, las funciones, la organización secuencial, las condiciones y estilos de la argumentación, el emisor y el receptor en la ...
Jesús Portillo Fernández
doaj  

Probabilistic argumentation

open access: yesJournal of Applied Logic, 2009
zbMATH Open Web Interface contents unavailable due to conflicting licenses.
openaire   +2 more sources

SPHINX31 acts as a SRPK1 inhibitor targeting the ATR/DNA‐PKcs/CHK1 replicative checkpoint to inhibit cell growth in non‐small cell lung cancer

open access: yesMolecular Oncology, EarlyView.
The kinase SRPK1 directly interacts with the protein TOPBP1 and regulates the pre‐mRNA splicing of WIZ thereby contributing to the activation of the ATR/CHK1 replicative checkpoint in response to replicative stress. This allows cancer cells' genomic stability and survival.
Amani Shreim   +17 more
wiley   +1 more source

Characterization of therapeutic antibodies targeting lymphatic and vascular resistance factor for the treatment of hypervascularized and highly metastatic cancers

open access: yesMolecular Oncology, EarlyView.
LVRF (lymphatic and vascular resistance factor) is a VEGFA splice variant upregulated in response to anti‐angiogenic therapy that fosters tumor adaptation through enhanced vascularization, lymphangiogenesis, and metastatic dissemination. Targeting LVRF with fully human neutralizing antibodies disrupts these processes and limits resistant tumor growth ...
Marion David   +12 more
wiley   +1 more source

A SCC Recursive Meta-Algorithm for Computing Preferred Labellings in Abstract Argumentation [PDF]

open access: yes, 2014
This paper presents a meta-algorithm for the computation of preferred labellings, based on the general recursive schema for argumentation semantics called SCC-Recursiveness.
Vallati, Mauro   +3 more
core   +2 more sources

Uses of the argumentation in the negotiation [PDF]

open access: yes
In the recent literature on conflict resolution tends to underline negotiation model based on the argument or dialogue. Exchange between different styles of argument some trends have emerged in the rhetoric applied to the law, especially in procedural ...
Estrada, Fernando
core  

Small RNA pathways in mammalian oocytes

open access: yesFEBS Open Bio, EarlyView.
Three distinct small RNA pathways operate in mammalian oocytes: RNAi interference (RNAi), the microRNA (miRNA) pathway, and the PIWI‐associated RNA (piRNA) pathway. These pathways use small RNAs to guide sequence‐specific repression and contribute to oocyte biology by targeting genes and mobile elements or appear insignificant since different ...
Petr Svoboda, Josef Pasulka
wiley   +1 more source

Argumentation-based fault diagnosis for home networks [PDF]

open access: yes, 2011
Home networks are a fast growing market but managing them is a difficult task, and diagnosing faults is even more challenging. Current fault management tools provide comprehensive information about the network and the devices but it is left to the user ...
Dong, Changyu   +3 more
core   +2 more sources

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