Results 101 to 110 of about 79,792 (314)

Small RNA pathways in mammalian oocytes

open access: yesFEBS Open Bio, EarlyView.
Three distinct small RNA pathways operate in mammalian oocytes: RNAi interference (RNAi), the microRNA (miRNA) pathway, and the PIWI‐associated RNA (piRNA) pathway. These pathways use small RNAs to guide sequence‐specific repression and contribute to oocyte biology by targeting genes and mobile elements or appear insignificant since different ...
Petr Svoboda, Josef Pasulka
wiley   +1 more source

Managing Social Influences through Argumentation-Based Negotiation

open access: yes, 2006
Social influences play an important part in the actions that an individual agent may perform within a multi-agent society. However, the incomplete knowledge and the diverse and conflicting influences present within such societies, may stop an agent from ...
Karunatillake, N. C.   +3 more
core  

On the problem of bias in political argumentation: an investigation into discussions about political asylum in Germany and Austria

open access: yes, 1997
Kienpointner M, Kindt W. On the problem of bias in political argumentation: an investigation into discussions about political asylum in Germany and Austria. Journal of Pragmatics.
Kindt, Walther, Kienpointner, Manfred
core   +1 more source

Hyperosmotic stress‐induced redistribution of pre‐mRNA cleavage factor I subunits is associated with shifts in alternative polyadenylation

open access: yesFEBS Open Bio, EarlyView.
Hyperosmotic stress triggers the relocation of the CFIm complex from the nucleus to the cytoplasm. This shift creates a nuclear ‘stoichiometric bottleneck’, limiting CFIm availability for mRNA processing. Consequently, specific mRNAs like NUDT21 and DICER1 undergo targeted 3′UTR shortening, demonstrating how spatial protein dynamics drive rapid ...
Hitomi Soumiya   +2 more
wiley   +1 more source

Argument Schemes from the Point of View of Hamblin’s Dialectic

open access: yesInformal Logic, 2011
This paper aims at a normative account of non-deductive argumentation schemes in the spirit of Hamblin’s dialectical philosophy. First, three principles are presented that characterize Hamblin’s dialectical stance.
Jan A. van Laar
doaj   +1 more source

Effects of IGFBP4 deficiency on human preadipocyte proliferation and differentiation through the IGF1R/AKT pathway

open access: yesFEBS Open Bio, EarlyView.
IGFBP4 knockdown (KD) impairs preadipocyte proliferation and is associated with IGF1R protein downregulation and attenuated AKT phosphorylation. The mechanisms by which IGFBP4 KD influences the IGF1R/AKT signaling pathway involve newly synthesized proteins and lysosomal degradation pathways. Created in BioRender.
Yujia Guo   +6 more
wiley   +1 more source

Application of jigsaw cooperative learning type based on socio scientific issues to improve argumentation skills on nervous system material

open access: yesAssimilation
The use of a jigsaw type cooperative learning model based on socioscientific issues in nervous system material can be used as a way to provide students with argumentation skills.
Fitri Husni Mardiyah   +2 more
doaj   +1 more source

Pragmatic aspects of task performance: The case of argumentation. [PDF]

open access: yes, 2001
The study reported in this paper investigated the pragmatic aspects of task-performance in a series of argumentation tasks that 24 Hungarian learners of English performed over a period of two years.
Németh, Nóra, Kormos, Judit
core  

Cutaneous Melanoma Drives Metabolic Changes in the Aged Bone Marrow Immune Microenvironment

open access: yesAging and Cancer, EarlyView.
Melanoma, the deadliest form of skin cancer, increasingly affects older adults. Our study reveals that melanoma induces changes in iron and lipid levels in the bone marrow, impacting immune cell populations and increasing susceptibility to ferroptosis.
Alexis E. Carey   +12 more
wiley   +1 more source

Complex Argumentation in Elementary School

open access: yesPNA: Revista de Investigación en Didáctica de la Matemática, 2019
This paper describes a study of mathematical argumentation in primary school. The principal aim is to explore the nature of complex argumentation at a structural level. The context of the study was a teaching experiment involving nine tasks that promoted
Jonathan Cervantes-Barraza   +2 more
doaj   +1 more source

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