Results 191 to 200 of about 9,406 (295)

Single‐Cell Dissection of Tumor‐Infiltrating Lymphocytes Reveals Cellular Architecture Predictive of Therapeutic Efficacy in Acral Melanoma

Advanced Science, EarlyView.
Autologous tumor‐infiltrating lymphocyte (TIL) therapy shows promising efficacy in acral melanoma, yet determinants of durable response remain unclear. By integrating single‐cell transcriptomics and TCR sequencing, this study reveals that TIL products enriched for T follicular helper and intermediate exhausted T cells establish persistent clonal ...
Chao Zhang, Wanyi Xiao, Hongru Shen, Fenge Li, Ting Li, Weihong Zhang, Haotian Liu, Ziwei Gao, Hongyu Wang, Xiubao Ren, Kexin Chen, Xiangchun Li, Jilong Yang   +12 more
wiley   +1 more source

The research program subjective theories: A methodological concept for a wide range of applications. [PDF]

GMS J Med Educ
Gadewoltz PN.
europepmc   +1 more source

Diving response : an argument for the aquatic ape theory in human evolution [PDF]

, 2017
Sander De Bock, Sarah de Jager, Janne Bouten, Jasmien Dumortier, Gil Bourgois, Eric Derom, J. H. Boone, Luc Herregods, Jan Bourgois   +8 more
openalex  

UCHL3 Regulates Subgenomic Flaviviral RNA Condensates to Promote Virus Propagation

Advanced Science, EarlyView.
ABSTRACT Flavivirus subgenomic RNAs (sfRNAs) antagonise antiviral defences, yet how sfRNAs are organized and maintained in cells remains poorly understood. Here we identify ubiquitin C‐terminal hydrolase L3 (UCHL3) as a post‐translational regulator of flavivirus sfRNA stability and function.
Oscar Trejo‐Cerro, Anna Beekmayer‐Dhillon, Qi Wen Teo, Lewis Siu, Ming Yuan Li, Kate J. Heesom, Adán Pinto‐Fernández, Sumana Sanyal   +7 more
wiley   +1 more source

Assessing the sustainable development of a national research ecosystem: A generative AI-based evaluation of empirical educational research in China (2004-2023). [PDF]

PLoS One
Wang S, Wang Y.
europepmc   +1 more source

The "Human Mental State Multiple Realizability in Silicon Thesis" is False: An Argument Against Computational Theories of Consciousness

, 2011
Matthew Stuart Piper
openalex   +1 more source

A re-examination and reinterpretation of the records of the presocratics and earlier from an ATR (Argumentative Theory of Reason) perspective : the development of reasoning in Greece in the form of “devising and evaluating arguments intended to persuade”

, 2017
Greg Armfield
openalex   +2 more sources

Studies on A. Einstein, B. Podolsky and N. Rosen argument that “quantum mechanics is not a complete theory,” II: Apparent confirmation of the EPR argument

, 2020
Ruggero María Santilli
openalex   +2 more sources

Large‐Scale Genomics Reveals Three‐Source Ancestry and Layered Adaptation to High Altitude in Tibetan Chickens

Advanced Science, EarlyView.
Whole‐genome analysis of 1,054 chickens reveals three ancestral sources (NWC, SYA, and SHF) with distinct temporal entry patterns into the Tibetan Plateau. Route‐specific selection scans, calibrated against a demographic null, suggest complementary functional enrichments—vascular homeostasis (NWC), calcium signaling and cardiac adaptation (SYA), and ...
Zongyi Zhao, Ruixue Nie, Hailu Fan, Tenzin Ngodroup, Li Zhu, Hongbin Pan, Bo Zhang, Hao Zhang   +7 more
wiley   +1 more source

Formal Argumentation Theory

The Reasoner
Sanjay Modgil
doaj