Results 251 to 260 of about 246,980 (329)

Designing High Performance Organic Donor Molecules for Photovoltaics

open access: yesAdvanced Theory and Simulations, EarlyView.
Systematically tuning the fusion pattern and length of the π$\pi$‐bridge, along with adjusting the electron‐withdrawing (EW) strength of the terminal groups in small‐molecule donor A-π-Core-π$\text{A-}\pi \text{-Core-}\pi$‐A architectures, enables predictable modulation of the system's opto‐electronic properties.
Fabian Bauch   +2 more
wiley   +1 more source

Allosteric Modulation of Pathological Ataxin‐3 Aggregation: A Path to Spinocerebellar Ataxia Type‐3 Therapies

open access: yesAdvanced Science, EarlyView.
This study uncovers a new allosteric site in the Josephin domain of ataxin‐3 targeted by the molecular tweezer CLR01, which modulates protein aggregation, improves synaptic function in neuronal cells, and delays motor dysfunction in animal models.
Alexandra Silva   +28 more
wiley   +1 more source

Structural and Functional Characterization of EXPO‐Derived Extracellular Vesicles in Plants

open access: yesAdvanced Science, EarlyView.
In this study, 3D electron tomography (ET), cryo‐ET, and immunogold transmission electron microscopy (TEM) are employed to characterize plant extracellular vesicles (EVs) under physiological conditions. EVs are classified into three distinct categories according to their size, content, and molecular‐marker profiles. Furthermore, Exo70E2‐positive medium
Jiayang Gao   +12 more
wiley   +1 more source

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